Ex Vivo Expanded Human Non-Cytotoxic CD8+CD45RClow/− Tregs Efficiently Delay Skin Graft Rejection and GVHD in Humanized Mice

Autor: Séverine Bézie, Dimitri Meistermann, Laetitia Boucault, Stéphanie Kilens, Johanna Zoppi, Elodie Autrusseau, Audrey Donnart, Véronique Nerrière-Daguin, Frédérique Bellier-Waast, Eric Charpentier, Franck Duteille, Laurent David, Ignacio Anegon, Carole Guillonneau

Publikováno v: Frontiers in Immunology, Vol 8 (2018)

Both CD4+ and CD8+ Tregs play a critical role in the control of immune responses and immune tolerance; however, our understanding of CD8+ Tregs is limited while they are particularly promising for therapeutic application. We report here existence of

Externí odkaz: https://doaj.org/article/71d6bb9052cf45bfbd9d8d426792782e

Optineurin regulates the interferon response in a cell cycle-dependent manner.

Autor: Pierre Génin, Frédérique Cuvelier, Sandrine Lambin, Josina Côrte-Real Filipe, Elodie Autrusseau, Christine Laurent, Emmanuel Laplantine, Robert Weil

Publikováno v: PLoS Pathogens, Vol 11, Iss 4, p e1004877 (2015)

Viral invasion into a host is initially recognized by the innate immune system, mainly through activation of the intracellular cytosolic signaling pathway and coordinated activation of interferon regulatory factor 3 (IRF3) and nuclear factor kappa B

Externí odkaz: https://doaj.org/article/3f2290a496d94de68143bd7a489a434a

Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–like Autoimmune Disease

Autor: Jason Ossart, Laurent Tesson, Laure-Hélène Ouisse, Léa Flippe, Elodie Autrusseau, Séverine Ménoret, Ignacio Anegon, Kai Kisand, François-Xavier Hubert, Régis Josien, Anne Moreau, Jerome Martin, Carole Guillonneau, Marine Besnard, Pärt Peterson

Publikováno v: Journal of Immunology
Journal of Immunology, 2018, 201 (3), pp.874-887. ⟨10.4049/jimmunol.1701318⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2018, 201 (3), pp.874-887. ⟨10.4049/jimmunol.1701318⟩

Autoimmune regulator (AIRE) deficiency in humans induces a life-threatening generalized autoimmune disease called autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy (APECED), and no curative treatments are available. Several models of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7d3b5de4e3bb758539354298108090
https://www.hal.inserm.fr/inserm-02156296

Optineurin Regulates the Interferon Response in a Cell Cycle-Dependent Manner

Autor: Elodie Autrusseau, Pierre Génin, Sandrine Lambin, Emmanuel Laplantine, Josina Côrte-Real Filipe, Frédérique Cuvelier, Robert Weil, Christine Laurent

Publikováno v: PLoS Pathogens
PLoS Pathogens, 2015, 11 (4), pp.e1004877. ⟨10.1371/journal.ppat.1004877⟩
PLoS Pathogens, Vol 11, Iss 4, p e1004877 (2015)
PLoS Pathogens, Public Library of Science, 2015, 11 (4), pp.e1004877. ⟨10.1371/journal.ppat.1004877⟩

Viral invasion into a host is initially recognized by the innate immune system, mainly through activation of the intracellular cytosolic signaling pathway and coordinated activation of interferon regulatory factor 3 (IRF3) and nuclear factor kappa B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d7e0fa561115901abb7c1d2b84e875
https://hal-pasteur.archives-ouvertes.fr/pasteur-01147388/document

NKT cell-plasmacytoid dendritic cell cooperation via OX40 controls viral infection in a tissue-specific manner

Autor: André Herbelin, Céline Tomkiewicz, Agnès Lehuen, Julien Diana, Thibault Griseri, Anne-Sophie Gautron, Lucie Beaudoin, Matthias von Herrath, Robert Barouki, Marc Dalod, Sylvie Lagaye, Elodie Autrusseau

Publikováno v: Immunity
Immunity, Elsevier, 2009, 30, pp.289-299
Immunity, Elsevier, 2009, 30 (2), pp.289-99. ⟨10.1016/j.immuni.2008.12.017⟩
Immunity, 2009, 30 (2), pp.289-99. ⟨10.1016/j.immuni.2008.12.017⟩
HAL
Immunity, Elsevier, 2009, 30 (2), pp.289-99. 〈10.1016/j.immuni.2008.12.017〉

International audience; Invariant natural killer T (iNKT) cells promote immune responses to various pathogens, but exactly how iNKT cells control antiviral responses is unclear. Here, we showed that iNKT cells induced tissue-specific antiviral effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98aa48d30b20127d6e3128e58b55c970
https://pubmed.ncbi.nlm.nih.gov/19217323