A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response

Autor: Alison Iroz, Alexandra Montagner, Fadila Benhamed, Françoise Levavasseur, Arnaud Polizzi, Elodie Anthony, Marion Régnier, Edwin Fouché, Céline Lukowicz, Michèle Cauzac, Emilie Tournier, Marcio Do-Cruzeiro, Martine Daujat-Chavanieu, Sabine Gerbal-Chalouin, Véronique Fauveau, Solenne Marmier, Anne-Françoise Burnol, Sandra Guilmeau, Yannick Lippi, Jean Girard, Walter Wahli, Renaud Dentin, Hervé Guillou, Catherine Postic

Publikováno v: Cell Reports, Vol 21, Iss 2, Pp 403-416 (2017)

Summary: While the physiological benefits of the fibroblast growth factor 21 (FGF21) hepatokine are documented in response to fasting, little information is available on Fgf21 regulation in a glucose-overload context. We report that peroxisome-prolif

Externí odkaz: https://doaj.org/article/27cfd3a0fbcd4dd49659cb793fec8873

Abstract 4101: ADRENALINE, an atlas for drug and breast cancer survival interaction: Comedications at diagnosis and impact on breast cancer mortality of the French breast cancer cohort (n=235,375)

Autor: Elise Dumas, Beatriz Grandal, Lucie Laot, Eric Daoud, Lidia Delrieu, Marc Espié, Sophie Houzard, Christine Le Bihan-Benjamin, Philippe-Jean Bousquet, Elodie Anthony, Aurélien Latouche, Nadir Sella, Thierry Dubois, Annabelle Ballesta, Amyn Kassara, Elaine Del Nery, Benjamin Marande, Samar Alsafadi, Paul Gougis, Chloé-Agathe Azencott, Fabien Reyal, Anne-Sophie Hamy

Publikováno v: Cancer Research. 82:4101-4101

Background: Breast cancer (BC) incidence increases with age, as well as the incidence of many other chronic diseases. Between 42 and 68% of BC patients suffer from other chronic conditions -comorbidities- at BC diagnosis. Comorbidities may be associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c8801d00ba882458389693a86cd36648
https://doi.org/10.1158/1538-7445.am2022-4101

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

Autor: Jèssica Latorre Luque, Marina Cardellini, Marc-Emmanuel Dumas, Gemma Xifra, Francesca Davato, Josep Puig, Vincent Blasco-Baque, Iris Cardolini, Elodie Anthony, José Manuel Fernández-Real, Fadila Benhamed, Laura Martinez-Gili, Massimo Federici, Rémy Burcelin, Wifredo Ricart, Lesley Hoyles, Julie Charpentier, Catherine Postic, Richard H. Barton, Frédéric Lopez, José María Moreno-Navarrete, Sarah Butcher, Antonis Myridakis, Matteo Serino, James Abbott, Fabienne Foufelle, Vincent Azalbert, Paolo Gentileschi, Christopher Tomlinson, Julien Chilloux, Christophe Heymes, Mark Woodbridge, Elaine Holmes, Ottavia Porzio, Jeremy K. Nicholson

Publikováno v: Nature Medicine
Nature Medicine, Nature Publishing Group, 2018, 24, pp.1070-1080. ⟨10.1038/s41591-018-0061-3⟩
Nature Medicine, Nature Publishing Group, 2018, 24 (7), pp.1070-1080. ⟨10.1038/s41591-018-0061-3⟩
Nature Medicine, 2018, 24 (7), pp.1070-1080. ⟨10.1038/s41591-018-0061-3⟩
Nature medicine

Hepatic steatosis is a multifactorial condition that is often observed in obese patients and is a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecal metagenomes with molecular phenomics (hepatic transcriptome a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0f5bc10166ab378b84a65b3472b5ef
https://irep.ntu.ac.uk/id/eprint/34314/1/11724_Hoyles.pdf

A Specific ChREBP and PPARα Cross-Talk Is Required for the Glucose-Mediated FGF21 Response

Autor: Anne-Françoise Burnol, Arnaud Polizzi, Marcio Do-Cruzeiro, Hervé Guillou, Emilie Tournier, Alison Iroz, Céline Lukowicz, Walter Wahli, Edwin Fouché, Solenne Marmier, Jean Girard, Renaud Dentin, Catherine Postic, Elodie Anthony, Fadila Benhamed, Françoise Levavasseur, Marion Régnier, Martine Daujat-Chavanieu, Yannick Lippi, Sandra Guilmeau, Véronique Fauveau, Sabine Gerbal-Chalouin, Michele Cauzac, Alexandra Montagner

Publikováno v: Cell Reports
Cell Reports, Elsevier Inc, 2017, 21 (2), pp.403-416. ⟨10.1016/j.celrep.2017.09.065⟩
Cell Reports 2 (21), 403-416. (2017)
Cell Reports, Vol 21, Iss 2, Pp 403-416 (2017)
Cell reports, vol. 21, no. 2, pp. 403-416

Summary While the physiological benefits of the fibroblast growth factor 21 (FGF21) hepatokine are documented in response to fasting, little information is available on Fgf21 regulation in a glucose-overload context. We report that peroxisome-prolife

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2440405e9afebdd2072ecbfc3a0088
https://hal.umontpellier.fr/hal-01837159

A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1

Autor: Jacques Camonis, Bruno Ragazzon, Frédéric Canal, Elaine Del Nery, Aurianne Lescure, Christine Perret, Franck Perez, Elodie Anthony

Publikováno v: BMC Cancer
BMC Cancer, BioMed Central, 2015, 15 (1), pp.1020. ⟨10.1186/s12885-015-2037-8⟩
BMC Cancer, 2015, 15 (1), pp.1020. ⟨10.1186/s12885-015-2037-8⟩
BMC Cancer, BioMed Central, 2015, 15 (1), pp.1020. 〈10.1186/s12885-015-2037-8〉

Background Aberrant activation of the Wnt/β-catenin pathway is a major and frequent event in liver cancer, but inhibition of oncogenic β-catenin signaling has proven challenging. The identification of genes that are synthetically lethal in β-caten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a5f37ac8cf2f6dd18b55d0c7ba0378
https://www.hal.inserm.fr/inserm-01254133/file/12885_2015_Article_2037.pdf