Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Elodie Angot"'
Autor:
Elodie Angot, Jennifer A Steiner, Carla M Lema Tomé, Peter Ekström, Bengt Mattsson, Anders Björklund, Patrik Brundin
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39465 (2012)
Several people with Parkinson's disease have been treated with intrastriatal grafts of fetal dopaminergic neurons. Following autopsy, 10-22 years after surgery, some of the grafted neurons contained Lewy bodies similar to those observed in the host b
Externí odkaz:
https://doaj.org/article/5c4ac7f09ca84bdf8002a98c409faba1
Autor:
Alina Schidlitzki, Milos Stanojlovic, Céline Fournier, Christopher Käufer, Malte Feja, Birthe Gericke, Marco Garzotti, Richard W.D. Welford, Michel Alexander Steiner, Elodie Angot, Franziska Richter
Publikováno v:
Movement Disorders.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72570159e1be686be94e93dc108b1d86
https://doi.org/10.1002/mds.29398
https://doi.org/10.1002/mds.29398
Publikováno v:
médecine/sciences. 27:979-985
The identification of a Sonic Hedgehog (Shh) signaling pathway in the adult vertebrate central nervous system has paved the way to the characterization of the functional roles of Shh signals in normal and diseased brain. This morphogen is proposed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7329d5855f6c89987d841dd360c5e71f
https://doi.org/10.1051/medsci/20112711014
https://doi.org/10.1051/medsci/20112711014
Publikováno v:
The Lancet Neurology. 9:1128-1138
A shared neuropathological feature of idiopathic Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy is the development of intracellular aggregates of α-synuclein that gradually engage increasing parts of the nervous system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be56736aa774ed120259d9416c509164
https://doi.org/10.1016/s1474-4422(10)70213-1
https://doi.org/10.1016/s1474-4422(10)70213-1
Publikováno v:
Journal of Neurochemistry. 113:576-590
The discovery of a Sonic Hedgehog (Shh) signaling pathway in the mature vertebrate CNS has paved the way to the characterization of the functional roles of Shh signals in normal and diseased brain. Shh is proposed to participate in the establishment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b30749ce0c00c45bd10195ba172726c4
https://doi.org/10.1111/j.1471-4159.2010.06642.x
https://doi.org/10.1111/j.1471-4159.2010.06642.x
Publikováno v:
L'Encéphale. 34:S201-S205
recapture de la 5-HT peuvent moduler le nombre et la sensibilite des recepteurs post-synaptiques. Ainsi des voies de signalisation couplees a l’adenylate cyclase ou la phospholipase C sont stimulees, augmentant les taux de seconds messagers (AMP cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2dff1ba7e3cb9baf67abe86a0737ca2
https://doi.org/10.1016/s0013-7006(08)75513-1
https://doi.org/10.1016/s0013-7006(08)75513-1
Publikováno v:
Glia
Glia, Wiley, 2014, 62 (3), pp.387-98. ⟨10.1002/glia.22611⟩
Glia, Wiley, 2014, 62 (3), pp.387-98. ⟨10.1002/glia.22611⟩
International audience; The origin of α-synuclein (α-syn)-positive glial cytoplasmic inclusions found in oligodendrocytes in multiple system atrophy (MSA) is enigmatic, given the fact that oligodendrocytes do not express α-syn mRNA. Recently, neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdda6752e20d6c806143b14d198b0647
https://hal.archives-ouvertes.fr/hal-01181201
https://hal.archives-ouvertes.fr/hal-01181201
Publikováno v:
Proteopathic Seeds and Neurodegenerative Diseases ISBN: 9783642354908
Parkinson’s disease is the second most prevalent neurodegenerative disease, affecting hundreds of thousands of people per year. Although the etiology of the disorder is unclear, recent studies have shown the key involvement of alpha-synuclein in PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3da567c15988c1aa917d41c0d5a08e6f
https://doi.org/10.1007/978-3-642-35491-5_8
https://doi.org/10.1007/978-3-642-35491-5_8
Publikováno v:
Cell Death and Differentiation; 18(9), pp 1425-1433 (2011)
Classically, Parkinson's disease (PD) is linked to dopamine neuron death in the substantia nigra pars compacta. Intracytoplasmic protein inclusions named Lewy bodies, and corresponding Lewy neurites found in neuronal processes, are also key features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d0bc1fdd3730da1847aad92cc8bcc2
https://lup.lub.lu.se/record/1972669
https://lup.lub.lu.se/record/1972669
Autor:
Patrik Brundin, Elodie Angot
Publikováno v:
Parkinsonismrelated disorders. 15
Alpha-synuclein (alpha-syn) aggregation is central to neuropathological changes in Parkinson's disease. The aggregates spread within the central nervous system according to a very predictable pattern. A prion-like transmission of alpha-syn aggregates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3407efcc4f9bce9c97911ad5336cc739
https://pubmed.ncbi.nlm.nih.gov/20082977
https://pubmed.ncbi.nlm.nih.gov/20082977