Zobrazeno 1 - 10 of 50 pro vyhledávání: '"Elodie, Mohr"'
1
Akademický článek
C-type lectin receptor agonists elicit functional IL21-expressing Tfh cells and induce primary B cell responses in neonates
Autor: Maria Vono, Beatris Mastelic-Gavillet, Elodie Mohr, Malin Östensson, Josefine Persson, Thorunn A. Olafsdottir, Sylvain Lemeille, David Pejoski, Oliver Hartley, Dennis Christensen, Peter Andersen, Arnaud M. Didierlaurent, Ali M. Harandi, Paul-Henri Lambert, Claire-Anne Siegrist
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
IntroductionC-type lectin receptor (CLR) agonists emerged as superior inducers of primary B cell responses in early life compared with Toll-like receptor (TLR) agonists, while both types of adjuvants are potent in adults.MethodsHere, we explored the
Externí odkaz: https://doaj.org/article/09b8465345674f77b4bc4ccc4f8b2f3e
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2
Akademický článek
CD39 and CD326 Are Bona Fide Markers of Murine and Human Plasma Cells and Identify a Bone Marrow Specific Plasma Cell Subpopulation in Lupus
Autor: Van Duc Dang, Elodie Mohr, Franziska Szelinski, Tuan Anh Le, Jacob Ritter, Timo Hinnenthal, Ana-Luisa Stefanski, Eva Schrezenmeier, Soeren Ocvirk, Christian Hipfl, Sebastian Hardt, Qingyu Cheng, Falk Hiepe, Max Löhning, Thomas Dörner, Andreia C. Lino
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
Antibody-secreting cells (ASCs) contribute to immunity through production of antibodies and cytokines. Identification of specific markers of ASC would allow selective targeting of these cells in several disease contexts. Here, we performed an unbiase
Externí odkaz: https://doaj.org/article/aec1b76a408c4dc9b4c3c3b29da5a094
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3
Akademický článek
Stromal Cell-Contact Dependent PI3K and APRIL Induced NF-κB Signaling Prevent Mitochondrial- and ER Stress Induced Death of Memory Plasma Cells
Autor: Rebecca Cornelis, Stefanie Hahne, Adriano Taddeo, Georg Petkau, Darya Malko, Pawel Durek, Manja Thiem, Lukas Heiberger, Lena Peter, Elodie Mohr, Cora Klaeden, Koji Tokoyoda, Francesco Siracusa, Bimba Franziska Hoyer, Falk Hiepe, Mir-Farzin Mashreghi, Fritz Melchers, Hyun-Dong Chang, Andreas Radbruch
Publikováno v: Cell Reports, Vol 32, Iss 5, Pp 107982- (2020)
Summary: The persistence of long-lived memory plasma cells in the bone marrow depends on survival factors available in the bone marrow, which are provided in niches organized by stromal cells. Using an ex vivo system in which we supply the known surv
Externí odkaz: https://doaj.org/article/98a5523b3ebf485e83c35f6851db7f1b
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4
Akademický článek
Identification of a super-functional Tfh-like subpopulation in murine lupus by pattern perception
Autor: Stefanie Gryzik, Yen Hoang, Timo Lischke, Elodie Mohr, Melanie Venzke, Isabelle Kadner, Josephine Poetzsch, Detlef Groth, Andreas Radbruch, Andreas Hutloff, Ria Baumgrass
Publikováno v: eLife, Vol 9 (2020)
Dysregulated cytokine expression by T cells plays a pivotal role in the pathogenesis of autoimmune diseases. However, the identification of the corresponding pathogenic subpopulations is a challenge, since a distinction between physiological variatio
Externí odkaz: https://doaj.org/article/b192ba23600248ffb4e36f9abad57946
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5
Akademický článek
Overcoming the Neonatal Limitations of Inducing Germinal Centers through Liposome-Based Adjuvants Including C-Type Lectin Agonists Trehalose Dibehenate or Curdlan
Autor: Maria Vono, Christiane Sigrid Eberhardt, Elodie Mohr, Floriane Auderset, Dennis Christensen, Mirco Schmolke, Rhea Coler, Andreas Meinke, Peter Andersen, Paul-Henri Lambert, Beatris Mastelic-Gavillet, Claire-Anne Siegrist
Publikováno v: Frontiers in Immunology, Vol 9 (2018)
Neonates and infants are more vulnerable to infections and show reduced responses to vaccination. Consequently, repeated immunizations are required to induce protection and early life vaccines against major pathogens such as influenza are yet unavail
Externí odkaz: https://doaj.org/article/9dd60d8b944f435ba82923ea937309da
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8
Akademický článek
A Theory of Germinal Center B Cell Selection, Division, and Exit
Autor: Michael Meyer-Hermann, Elodie Mohr, Nadége Pelletier, Yang Zhang, Gabriel D. Victora, Kai-Michael Toellner
Publikováno v: Cell Reports, Vol 2, Iss 1, Pp 162-174 (2012)
High-affinity antibodies are generated in germinal centers in a process involving mutation and selection of B cells. Information processing in germinal center reactions has been investigated in a number of recent experiments. These have revealed cell
Externí odkaz: https://doaj.org/article/ed181baa017f42578bd7014f1f3536b2
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10
Akademický článek
Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.
Autor: Karine Serre, Cécile Bénézech, Guillaume Desanti, Saeeda Bobat, Kai-Michael Toellner, Roger Bird, Susan Chan, Philippe Kastner, Adam F Cunningham, Ian C M Maclennan, Elodie Mohr
Publikováno v: PLoS ONE, Vol 6, Iss 6, p e20731 (2011)
BACKGROUND:Although in vitro IL-4 directs CD4 T cells to produce T helper 2 (Th2)-cytokines, these cytokines can be induced in vivo in the absence of IL-4-signalling. Thus, mechanism(s), different from the in vitro pathway for Th2-induction, contribu
Externí odkaz: https://doaj.org/article/cc8a133ab69344678538562796e35e36
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