Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Elodie, Laine"'
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-17 (2024)
Abstract Proteins play a central role in biological processes, and understanding their conformational variability is crucial for unraveling their functional mechanisms. Recent advancements in high-throughput technologies have enhanced our knowledge o
Externí odkaz:
https://doaj.org/article/75ad3ee47e6c4b1ba5770fc21d9f9a07
Autor:
Salomé Nashed, Houssam El Barbry, Médine Benchouaia, Angélie Dijoux-Maréchal, Thierry Delaveau, Nadia Ruiz-Gutierrez, Lucie Gaulier, Déborah Tribouillard-Tanvier, Guillaume Chevreux, Stéphane Le Crom, Benoit Palancade, Frédéric Devaux, Elodie Laine, Mathilde Garcia
Publikováno v:
PLoS Genetics, Vol 19, Iss 8, p e1010848 (2023)
N-terminal ends of polypeptides are critical for the selective co-translational recruitment of N-terminal modification enzymes. However, it is unknown whether specific N-terminal signatures differentially regulate protein fate according to their cell
Externí odkaz:
https://doaj.org/article/27f57877027b4bf1a96a603d340084e3
Autor:
Yasaman Karami, Paul Saighi, Rémy Vanderhaegen, Denis Gerlier, Sonia Longhi, Elodie Laine, Alessandra Carbone
Publikováno v:
BMC Bioinformatics, Vol 21, Iss S19, Pp 1-20 (2020)
Abstract Background Coiled-coils are described as stable structural motifs, where two or more helices wind around each other. However, coiled-coils are associated with local mobility and intrinsic disorder. Intrinsically disordered regions in protein
Externí odkaz:
https://doaj.org/article/c4b97fa0ca044aaea8f46b21eb323d2d
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 1, p e1009825 (2022)
Proteins ensure their biological functions by interacting with each other. Hence, characterising protein interactions is fundamental for our understanding of the cellular machinery, and for improving medicine and bioengineering. Over the past years,
Externí odkaz:
https://doaj.org/article/67e04305264c4f1db1e89f2d7d462b05
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 2, p e1007624 (2020)
Interactions between proteins and nucleic acids are at the heart of many essential biological processes. Despite increasing structural information about how these interactions may take place, our understanding of the usage made of protein surfaces by
Externí odkaz:
https://doaj.org/article/8b5993df380d447e96230e53eead5306
Alternative splicing of repeats in proteins provides a mechanism for rewiring and fine-tuning protein interaction networks. In this work, we developed a robust and versatile method, ASPRING, to identify alternatively spliced protein repeats from gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92600aacd5f8c5906528aa8ff113b00a
https://doi.org/10.1101/2023.04.29.538821
https://doi.org/10.1101/2023.04.29.538821
Autor:
Kotaro Tsuboyama, Justas Dauparas, Jonathan Chen, Elodie Laine, Yasser Mohseni Behbahani, Jonathan J. Weinstein, Niall M. Mangan, Sergey Ovchinnikov, Gabriel J. Rocklin
Datasets and scriptsfor BioRixv manuscript titled "Mega-scale experimental analysis of protein folding stability in biology and protein design" URL:https://doi.org/10.1101/2022.12.06.519132 *** IMPORTANT! Pleaseregister your useof these data so that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c29576efc048a875a7591248b13d35
Autor:
Betty Gardie, Stéphane Richard, Peter Ratcliffe, William Kaelin, David R. Mole, Luba Tchertanov, Philippe Dessen, Nathalie M. Mazure, Anne-Paule Gimenez-Roqueplo, Vladimir Lazar, Jean Feunteun, Brigitte Bressac-de Paillerets, Patrick R. Benusiglio, Françoise Lasne, Christine Collin, Jean-Christophe Pagès, Bernard Lecomte, William Y. Kim, Gregory Nuel, Marion Le Gentil, Hélène Le Jeune, Sophie Gad, Justine Guégan, Karène Mahtouk, Elodie Laine, Charline Ladroue, Sophie Couvé
Table S1: Phenotypes associated with single R161Q and R200W VHL germline mutations are different from the phenotype associated with the combined mutations. Table S2: VHL mutations associated with polycythemia are different from the VHL mutations invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12195e1a1eadc82a060397742b583b8e
https://doi.org/10.1158/0008-5472.22403115.v1
https://doi.org/10.1158/0008-5472.22403115.v1
Autor:
Betty Gardie, Stéphane Richard, Peter Ratcliffe, William Kaelin, David R. Mole, Luba Tchertanov, Philippe Dessen, Nathalie M. Mazure, Anne-Paule Gimenez-Roqueplo, Vladimir Lazar, Jean Feunteun, Brigitte Bressac-de Paillerets, Patrick R. Benusiglio, Françoise Lasne, Christine Collin, Jean-Christophe Pagès, Bernard Lecomte, William Y. Kim, Gregory Nuel, Marion Le Gentil, Hélène Le Jeune, Sophie Gad, Justine Guégan, Karène Mahtouk, Elodie Laine, Charline Ladroue, Sophie Couvé
Supplementary Material and Methods and Legend of Supplementary Tables and Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90041a881bdb670ed79fc0acd2c2f01a
https://doi.org/10.1158/0008-5472.22403121
https://doi.org/10.1158/0008-5472.22403121
Autor:
Nika Abdollahi, Alexandre Albani, Eric Anthony, Agnes Baud, Mélissa Cardon, Robert Clerc, Dariusz Czernecki, Romain Conte, Laurent David, Agathe Delaune, Samia Djerroud, Pauline Fourgoux, Nadège Guiglielmoni, Jeanne Laurentie, Nathalie Lehmann, Camille Lochard, Rémi Montagne, Vasiliki Myrodia, Vaitea Opuu, Elise Parey, Lélia Polit, Sylvain Privé, Chloé Quignot, Maria Ruiz-Cuevas, Mariam Sissoko, Nicolas Sompairac, Audrey Vallerix, Violaine Verrecchia, Marc Delarue, Raphael Guérois, Yann Ponty, Sophie Sacquin-Mora, Alessandra Carbone, Christine Froidevaux, Stéphane Le Crom, Olivier Lespinet, Martin Weigt, Samer Abboud, Juliana Bernardes, Guillaume Bouvier, Chloé Dequeker, Arnaud Ferré, Patrick Fuchs, Gaëlle Lelandais, Pierre Poulain, Hugues Richard, Hugo Schweke, Elodie Laine, Anne Lopes
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 3, p e1005992 (2018)
We present a new educational initiative called Meet-U that aims to train students for collaborative work in computational biology and to bridge the gap between education and research. Meet-U mimics the setup of collaborative research projects and tak
Externí odkaz:
https://doaj.org/article/e780d76873364d1588f1c361ea6d3e72