Quality assessment of a serum and xenofree medium for the expansion of human GMP-grade mesenchymal stromal cells

Autor: Clotilde Aussel, Elodie Busson, Helene Vantomme, Juliette Peltzer, Christophe Martinaud

Publikováno v: PeerJ, Vol 10, p e13391 (2022)

Background Cell-based therapies are emerging as a viable modality to treat challenging diseases, resulting in an increasing demand for their large-scale, high-quality production. Production facilities face the issue of batch-to-batch consistency whil

Externí odkaz: https://doaj.org/article/89c490c3d25d4f348870176cc0686fff

Mesenchymal Stromal Cells Based Therapy in Systemic Sclerosis: Rational and Challenges

Autor: Juliette Peltzer, Marc Aletti, Nadira Frescaline, Elodie Busson, Jean-Jacques Lataillade, Christophe Martinaud

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Systemic Sclerosis (SSc) is a rare chronic disease, related to autoimmune connective tissue diseases such as Systemic Lupus Erythematosus and Sjögren's Syndrome. Although its clinical heterogeneity, main features of the disease are: extensive tissue

Externí odkaz: https://doaj.org/article/222e9dabaf5c4ed0aedb385210026076

Fibroblasts from the Human Skin Dermo-Hypodermal Junction are Distinct from Dermal Papillary and Reticular Fibroblasts and from Mesenchymal Stem Cells and Exhibit a Specific Molecular Profile Related to Extracellular Matrix Organization and Modeling

Autor: Véronique Neiveyans, Nicolas O. Fortunel, Daniel Asselineau, Philippe Perez, Jean-Jacques Lataillade, Valérie Haydont, Elodie Busson

Publikováno v: Cells, Vol 9, Iss 2, p 368 (2020)
Cells
Volume 9
Issue 2

Human skin dermis contains fibroblast subpopulations in which characterization is crucial due to their roles in extracellular matrix (ECM) biology. This study investigates the properties of fibroblasts localized at the frontier of deep dermis and hyp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d5e38516430cc68a3ab201b4858e8d
https://www.mdpi.com/2073-4409/9/2/368

Autologous Bone Marrow Mesenchymal Stem Cells Improve the Quality and Stability of Vascularized Flap Surgery of Irradiated Skin in Pigs

Autor: Christine, Linard, Michel, Brachet, Carine, Strup-Perrot, Bruno, L'homme, Elodie, Busson, Claire, Squiban, Valerie, Holler, Michel, Bonneau, Jean-Jacques, Lataillade, Eric, Bey, Marc, Benderitter

Publikováno v: Stem Cells Translational Medicine
Stem Cells Translational Medicine, Wiley, 2018, 7 (8), pp.569-582. ⟨10.1002/sctm.17-0267⟩

Cutaneous radiation syndrome has severe long‐term health consequences. Because it causes an unpredictable course of inflammatory waves, conventional surgical treatment is ineffective and often leads to a fibronecrotic process. Data about the long�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f658d89d10492d3f050d59f53aa83dd7
https://hal.inrae.fr/hal-02626486

High proportion of PD-1-expressing CD4 + T cells in adipose tissue constitutes an immunomodulatory microenvironment that may support HIV persistence

Autor: Guillaume Pourcher, Abderaouf Damouche, Benoit Favier, Jean Jacques Lataillade, Bruno Vaslin, Valérie Pourcher, Christine Bourgeois, Elodie Busson, Olivier Lambotte, Mélanie Le Van, Stéphane Benoist, Thierry Lazure, Julien Adam, Michaela Müller-Trutwin

Publikováno v: European Journal of Immunology
European Journal of Immunology, 2017, 47 (12), pp.2113-2123. ⟨10.1002/eji.201747060⟩
European Journal of Immunology, Wiley-VCH Verlag, 2017, 47 (12), pp.2113-2123. ⟨10.1002/eji.201747060⟩

We and others have demonstrated that adipose tissue is a reservoir for HIV. Evaluation of the mechanisms responsible for viral persistence may lead to ways of reducing these reservoirs. Here, we evaluated the immune characteristics of adipose tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfca3eda57bdcf8b871126b640f92b28
https://doi.org/10.1002/eji.201747060