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Human Alpha-1 Antitrypsin Attenuates ENaC and MARCKS and Lowers Blood Pressure in Hypertensive Diabetic db/db Mice.

Autor: Lugo CI; Department of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA., Liu LP; Department of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA., Bala N; Department of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA., Morales AG; Department of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA., Gholam MF; Department of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA.; Department of Basic Medical Sciences, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah 21423, Saudi Arabia., Abchee JC; Department of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA., Elmoujahid N; Department of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA., Elshikha AS; Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA.; Department of Pharmaceutics, University of Florida College of Pharmacy, Gainesville, FL 32610, USA., Avdiaj R; Department of Pharmaceutics, University of Florida College of Pharmacy, Gainesville, FL 32610, USA., Searcy LA; Department of Physiological Sciences and Center for Environmental and Human Toxicology, University of Florida College of Veterinary Medicine, Gainesville, FL 32610, USA., Denslow ND; Department of Physiological Sciences and Center for Environmental and Human Toxicology, University of Florida College of Veterinary Medicine, Gainesville, FL 32610, USA., Song S; Department of Pharmaceutics, University of Florida College of Pharmacy, Gainesville, FL 32610, USA., Alli AA; Department of Physiology and Aging, University of Florida College of Medicine, Gainesville, FL 32610, USA.; Department of Medicine Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida College of Medicine, Gainesville, FL 32610, USA.

Publikováno v: Biomolecules [Biomolecules] 2022 Dec 29; Vol. 13 (1). Date of Electronic Publication: 2022 Dec 29.