Thymol Protects against 5-Fluorouracil-Induced Hepatotoxicity via the Regulation of the Akt/GSK-3β Pathway in In Vivo and In Silico Experimental Models.

Autor: Mahran YF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt., Badr AM; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia., Al-Kharashi LA; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia., Alajami HN; College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia., Aldamry NT; Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh 11211, Saudi Arabia., Bayoumy NM; Department of Physiology, College of Medicine, King Saud University, Riyadh 11211, Saudi Arabia., Elmongy EI; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo 11795, Egypt., Soliman S; Department of Physiology and Pharmacology, College of Osteopathic Medicine, Sam Houston State University, Conroe, TX 77304, USA.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2024 Aug 21; Vol. 17 (8). Date of Electronic Publication: 2024 Aug 21.

Synthesis and molecular docking study of α-aminophosphonates as potential multi-targeting antibacterial agents.

Autor: Neiber RR; Beijing Key Laboratory of Ionic Liquids Clean Process, CAS Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, 100190 Beijing, China; College of Chemical Engineering, University of Chinese Academy of Sciences, 19 A Yuquan Road, 100049 Beijing, China; School of Chemistry and Chemical Engineering, University of Chinese Academy of Sciences, 100049 Beijing, China., Samak NA; College of Chemical Engineering, University of Chinese Academy of Sciences, 19 A Yuquan Road, 100049 Beijing, China; CAS Key Laboratory of Green Process and Engineering & State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China; Aquatic microbiology department, Faculty of Chemistry, University of Duisburg-Essen, 45141 Essen, Germany. Electronic address: nadia@ipe.ac.cn., Xing J; College of Chemical Engineering, University of Chinese Academy of Sciences, 19 A Yuquan Road, 100049 Beijing, China; CAS Key Laboratory of Green Process and Engineering & State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China., Elmongy EI; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. BOX 84428, Riyadh 11671, Saudi Arabia., Galhoum AA; Nuclear Materials Authority, P.O. Box 530, El-Maadi, Cairo, Egypt. Electronic address: galhoum_nma@yahoo.com., El Sayed IE; Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Kom, Egypt. Electronic address: ibrahimtantawy@yahoo.co.uk., Guibal E; Institut Mines Telecom-Mines Alès, C2MA, 6 avenue de Clavières, F-30319 Alès cedex, France., Xin J; Beijing Key Laboratory of Ionic Liquids Clean Process, CAS Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, 100190 Beijing, China; School of Chemistry and Chemical Engineering, University of Chinese Academy of Sciences, 100049 Beijing, China; Innovation Academy for Green Manufacture, Chinese Academy of Sciences, Beijing 100190, China., Lu X; Beijing Key Laboratory of Ionic Liquids Clean Process, CAS Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, 100190 Beijing, China; School of Chemistry and Chemical Engineering, University of Chinese Academy of Sciences, 100049 Beijing, China; Innovation Academy for Green Manufacture, Chinese Academy of Sciences, Beijing 100190, China; Department of Chemistry, University of Chinese Academy of Sciences, 100049 Beijing, China. Electronic address: xmlu@ipe.ac.cn.

Publikováno v: Journal of hazardous materials [J Hazard Mater] 2024 Mar 05; Vol. 465, pp. 133203. Date of Electronic Publication: 2023 Dec 12.

Synthesis and in-vitro anti-proliferative with antimicrobial activity of new coumarin containing heterocycles hybrids.

Autor: Abdelaziz E; Department of Chemistry, Faculty of Science, Menoufia University, Menoufia, Egypt., El-Deeb NM; Biopharmaceutical Products Research Department, Genetic Engineering and Biotechnology Research Institute (GEBRI) City of Scientific Research and Technological Applications (SRTA-City) Alexandria, New Borg El-Arab City, 21934, Egypt., Zayed MF; Department of Chemistry, Faculty of Science, Menoufia University, Menoufia, Egypt., Hasanein AM; Department of Chemistry, Faculty of Science, Menoufia University, Menoufia, Egypt., El Sayed IE; Department of Chemistry, Faculty of Science, Menoufia University, Menoufia, Egypt. Ibrahimtantawy@yahoo.co.uk., Elmongy EI; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Ain Helwan, P.O. Box 11795, Cairo, Egypt., Kamoun EA; Polymeric Materials Research Department, Advanced Technology and New Materials Research Institute (ATNMRI), City of Scientific Research and Technological Applications (SRTA-City, Alexandria, New Borg El-Arab City, 21934, Egypt. badawykamoun@yahoo.com.; Nanotechnology Research Center (NTRC), The British University in Egypt (BUE), El-Sherouk City, Cairo, Egypt. badawykamoun@yahoo.com.

Publikováno v: Scientific reports [Sci Rep] 2023 Dec 21; Vol. 13 (1), pp. 22791. Date of Electronic Publication: 2023 Dec 21.

In vivo and In silico evidence of the protective properties of carvacrol against experimentally-induced gastric ulcer: Implication of antioxidant, anti-inflammatory, and antiapoptotic mechanisms.

Autor: Badr AM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, King Saud University, Riyadh, Saudi Arabia., El-Orabi NF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Suez Canal University, Ismailia, Egypt., Mahran YF; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Abasia, Cairo, Egypt., Badr AM; Department of Medical Biochemistry and Molecular Biology, Kasr Al-Aini Faculty of Medicine, Cairo University, Egypt., Bayoumy NM; Department of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Hagar H; Department of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Elmongy EI; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo, Egypt., Atawia RT; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Abasia, Cairo, Egypt; Department of Pharmaceutical Sciences, College of Pharmacy, Southwestern Oklahoma State University, Weatherford, OK, United States. Electronic address: reemtarekatawia@pharma.asu.edu.eg.

Publikováno v: Chemico-biological interactions [Chem Biol Interact] 2023 Sep 01; Vol. 382, pp. 110649. Date of Electronic Publication: 2023 Jul 25.

Synthesis, Characterization, and Docking Study of Novel Thioureidophosphonate-Incorporated Silver Nanocomposites as Potent Antibacterial Agents.

Autor: El-Tantawy AI; Department of Chemistry, Faculty of Science, Menoufia University, Shibin El Kom 32511, Egypt., Elmongy EI; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia., Elsaeed SM; Department of Analysis and Evaluation, Egyptian Petroleum Research Institute, Cairo 11727, Egypt., Abdel Aleem AAH; Department of Chemistry, Faculty of Science, Menoufia University, Shibin El Kom 32511, Egypt., Binsuwaidan R; Department of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia., Eisa WH; Spectroscopy Department, Physics Division, National Research Centre (NRC), Cairo 12622, Egypt., Salman AU; Department of Botany and Microbiology, Faculty of Science, Menoufia University, Shibin El Kom 32511, Egypt., Elharony NE; Department of Chemistry, Faculty of Science, Menoufia University, Shibin El Kom 32511, Egypt., Attia NF; Gas Analysis and Fire Safety Laboratory, Chemistry Division, National Institute for Standards, 136, Giza 12211, Egypt.

Publikováno v: Pharmaceutics [Pharmaceutics] 2023 Jun 06; Vol. 15 (6). Date of Electronic Publication: 2023 Jun 06.