Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Elmira I, Yakupova"'
Autor:
Valentina A. Babenko, Elmira I. Yakupova, Irina B. Pevzner, Alexey D. Bocharnikov, Ljubava D. Zorova, Kseniya S. Fedulova, Oleg A. Grebenchikov, Artem N. Kuzovlev, Andrey V. Grechko, Denis N. Silachev, Parvaneh Rahimi-Moghaddam, Egor Y. Plotnikov
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1325 (2024)
Thrombolytic therapy with the tissue plasminogen activator (tPA) is a therapeutic option for acute ischemic stroke. However, this approach is subject to several limitations, particularly the increased risk of hemorrhagic transformation (HT). Lithium
Externí odkaz:
https://doaj.org/article/cdb7a54beeea4608bb0d04aed0c173a6
Autor:
Ljubava D. Zorova, Polina A. Abramicheva, Nadezda V. Andrianova, Valentina A. Babenko, Savva D. Zorov, Irina B. Pevzner, Vasily A. Popkov, Dmitry S. Semenovich, Elmira I. Yakupova, Denis N. Silachev, Egor Y. Plotnikov, Gennady T. Sukhikh, Dmitry B. Zorov
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 444 (2024)
There is an increasing accumulation of data on the exceptional importance of mitochondria in the occurrence and treatment of cancer, and in all lines of evidence for such participation, there are both energetic and non-bioenergetic functional feature
Externí odkaz:
https://doaj.org/article/38d508068aea40768673ccc6e47e2a94
Autor:
Viktoriya V. Antonova, Denis N. Silachev, Egor Y. Plotnikov, Irina B. Pevzner, Elmira I. Yakupova, Mikhail V. Pisarev, Ekaterina A. Boeva, Zoya I. Tsokolaeva, Maxim A. Lyubomudrov, Igor V. Shumov, Andrey V. Grechko, Oleg A. Grebenchikov
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 635 (2024)
This is the first in vivo study to investigate the neuroprotective effects of krypton on focal cerebral ischemia. The aim of the study was to analyze the effect of 2 h of inhalation of a krypton–oxygen mixture (Kr 70%/O2 30%) on the recovery of neu
Externí odkaz:
https://doaj.org/article/03fd0561597c4ce0af6cfb585b125c68
Autor:
Elmira I. Yakupova, Liya G. Bobyleva, Sergey A. Shumeyko, Ivan M. Vikhlyantsev, Alexander G. Bobylev
Publikováno v:
Biology, Vol 10, Iss 5, p 394 (2021)
Proteins can perform their specific function due to their molecular structure. Partial or complete unfolding of the polypeptide chain may lead to the misfolding and aggregation of proteins in turn, resulting in the formation of different structures s
Externí odkaz:
https://doaj.org/article/4acabea1aeb34d0eb95667ab2f290f1e
Publikováno v:
Exp Biol Med (Maywood)
Macrophages, the key cells of innate immunity, possess wide phenotypical and functional heterogeneity. In vitro studies showed that microenvironment signals could induce the so-called polarization of macrophages into two phenotypes: classically activ
Autor:
Alexander G. Bobylev, Elmira I. Yakupova, Liya G. Bobyleva, Nikolay V. Molochkov, Alexander A. Timchenko, Maria A. Timchenko, Hiroshi Kihara, Alexey D. Nikulin, Azat G. Gabdulkhakov, Tatiana N. Melnik, Nikita V. Penkov, Michail Y. Lobanov, Alexey S. Kazakov, Miklós Kellermayer, Zsolt Mártonfalvi, Oxana V. Galzitskaya, Ivan M. Vikhlyantsev
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1056
A giant multidomain protein of striated and smooth vertebrate muscles, titin, consists of tandems of immunoglobulin (Ig)- and fibronectin type III (FnIII)-like domains representing β-sandwiches, as well as of disordered segments. Chicken smooth musc
Publikováno v:
Biochemistry (Moscow). 86:1599-1606
It is known that the development of fibrosis is associated with many diseases, being both a cause and effect of the damage to organs and tissues. Replacement of functional tissue with a scar can lead to organ dysfunction, which is often a life-threat
Publikováno v:
Nutrients. 14(18)
Dietary intervention is widely used as a therapeutic approach ranging from the treatment of neurological disorders to attempts to extend lifespan. The most important effect of various diets is a change in energy metabolism. Since muscles constitute 4
Publikováno v:
Biophysics. 65:18-21
—Here, we consider the problem of the activation of the complement system by amyloid aggregates, in particular, amyloid fibrils of the Aβ(1-40) and Aβ(1-42) peptides found in the brain of patients with Alzheimer’s disease . In 1992, based on th
Autor:
Oxana V. Galzitskaya, Ivan M. Vikhlyantsev, Elmira I Yakupova, A. G. Bobylev, Sergey A Shumeyko, Alexey D. Nikulin, D. A. Yurshenas, L. G. Bobyleva
Publikováno v:
Молекулярная биология. 54:643-652
In this paper, the property of the muscle titin protein to form in vitro specific amyloid-like aggregates is discussed. The main difference from the known amyloid aggregates is the formation of a quaternary structure that resembles cross-β, with no