Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Elmira Anderzhanova"'
Autor:
Alhasan Abdulghani, Mikayel Poghosyan, Aylin Mehren, Alexandra Philipsen, Elmira Anderzhanova
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2023)
Adaptive neuroplasticity is a pivotal mechanism for healthy brain development and maintenance, as well as its restoration in disease- and age-associated decline. Management of mental disorders such as attention deficit hyperactivity disorder (ADHD) n
Externí odkaz:
https://doaj.org/article/1d297d7c0b4a4ea4b42234173df9076e
Autor:
Elmira Anderzhanova, Kathrin Hafner, Andreas J. Genewsky, Azza Soliman, Max L. Pöhlmann, Mathias V. Schmidt, Robert Blum, Carsten T. Wotjak, Nils C. Gassen
Publikováno v:
Neurobiology of Stress, Vol 13, Iss , Pp 100239- (2020)
We report here the involvement of the stress-responsive glucocorticoid receptor co-chaperone FKBP51 in the mechanism of in vivo secretion of mature BDNF (mBDNF). We used a novel method combining brain microdialysis with a capillary electrophoresis-ba
Externí odkaz:
https://doaj.org/article/ba9dc9550c154b748dfb9f788b2c2d28
Autor:
Shaul Lerner, Elmira Anderzhanova, Sima Verbitsky, Raya Eilam, Yael Kuperman, Michael Tsoory, Yuri Kuznetsov, Alexander Brandis, Tevie Mehlman, Ram Mazkereth, Robert McCarter, Menahem Segal, Sandesh C.S. Nagamani, Alon Chen, Ayelet Erez, Fabienne Dietrich Alber, Talin Babikian, Heidi Bender, Christopher Boys, David Breiger, Corinna Buerger, Peter Burgard, Mina Nguyen-Driver, Benjamin Goodlett, Elizabeth Kerr, Casey Krueger, Eva Mamak, Jacqueline H. Sanz, David Schwartz, Susan Caudle, Arianna Stefanos, Rachel Tangen, Magdalena Walter, Susan Waisbren, Greta Wilkening
Publikováno v:
Cell Reports, Vol 29, Iss 8, Pp 2144-2153.e7 (2019)
Summary: Patients with germline mutations in the urea-cycle enzyme argininosuccinate lyase (ASL) are at risk for developing neurobehavioral and cognitive deficits. We find that ASL is prominently expressed in the nucleus locus coeruleus (LC), the cen
Externí odkaz:
https://doaj.org/article/976ff388391d44aba3c02d09b832485b
Publikováno v:
Neurobiology of Stress, Vol 7, Iss , Pp 47-56 (2017)
The recently proposed Research Domain Criteria (RDoC) system defines psychopathologies as phenomena of multilevel neurobiological existence and assigns them to 5 behavioural domains characterizing a brain in action. We performed an analysis on this c
Externí odkaz:
https://doaj.org/article/863d2f1a349d4b718033383fe6cb4098
Publikováno v:
Frontiers in Psychiatry, Vol 9 (2018)
Discovery of the Hippo pathway and its core components has made a significant impact on our progress in the understanding of organ development, tissue homeostasis, and regeneration. Upon diverse extracellular and intracellular stimuli, Hippo signalin
Externí odkaz:
https://doaj.org/article/e242d999ebbf49558cdc60df44fc8241
Autor:
Claudia Kühne, Osborne F. X. Almeida, Nils C. Gassen, Elmira Anderzhanova, Ioannis Sotiropoulos, Chrysoula Dioli, Anna Pissioti, Mazen R. Harb, Alexandre V. Patchev, C. Catania, Este Leidmaa, Rainer Stoffel, Shuang Yu, Mary Gazea, Susanne Moosecker
Publikováno v:
Neuroscience. 479:91-106
Like other members of the superfamily of nuclear receptors, the peroxisome proliferator-activated receptor γ (PPARγ), is a ligand-activated transcription factor known for its insulin-sensitizing actions in the periphery. Despite only sparse evidenc
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion
Autor:
Felix Hausch, Daniel E. Heinz, Valentin Stein, Ulrike Schmidt, Frederik Dethloff, Lee Jollans, Max L. Pöhlmann, Bernhard Kuster, Katja Weckmann, Kathrin Hafner, Elmira Anderzhanova, Svenja Wiechmann, Thomas M. Geiger, Thomas Bajaj, Jakob Hartmann, Tim Ebert, Christoph W. Turck, Nils C. Gassen, Alexandra Philipsen, Mathias V. Schmidt, Susanne Schmidt, Giuseppina Maccarrone, Michael Döngi, Anne-Kathrin Gellner, Silvia Martinelli
Publikováno v:
Nature Communications, 12(1):4643. Nature Publishing Group
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The stress response is an essential mechanism for maintaining homeostasis, and its disruption is implicated in several psychiatric disorders. On the cellular level, stress activates, among other mechanisms, autophagy that regulates homeostasis throug
Autor:
Elena Brivio, Carine Dournes, Jan M. Deussing, Marcel Schieven, Juan-Pablo Lopez, Rainer Stoffel, Carola Eggert, Claudia Kuehne, Maria Holzapfel, Rosa-Eva Huettl, Julien Dine, Simone Roeh, Mira Jakovcevski, Lisa Tietze, Elmira Anderzhanova, Alon Chen
Short abstractHabituation of the hypothalamic-pituitary-adrenal (HPA) axis to repeated homotypic stressors is crucial for the organism’s well-being. Many physiological and psychological disorders are associated with HPA axis dysfunction. Here, we s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4572cc258939e77168675cd53824a801
https://doi.org/10.1101/2020.11.30.402024
https://doi.org/10.1101/2020.11.30.402024
Publikováno v:
Neurobiology of Stress
Neurobiology of Stress, Vol 7, Iss, Pp 47-56 (2017)
Neurobiology of stress
Neurobiology of Stress, Vol 7, Iss, Pp 47-56 (2017)
Neurobiology of stress
The recently proposed Research Domain Criteria (RDoC) system defines psychopathologies as phenomena of multilevel neurobiological existence and assigns them to 5 behavioural domains characterizing a brain in action. We performed an analysis on this c
Autor:
Elmira Anderzhanova, Julien Dine, Carsten T. Wotjak, Wolfgang Wurst, Annette M. Vogl, Mathias V. Schmidt, Jakob Hartmann, Bianca Schmid, Rafael Carvalho Almada, Valery Grinevich, Damian Refojo, Max L. Pöhlmann, Nina Dedic, Kerry J. Ressler, Simon Chang, Andreas Genewsky, Karina S. Gomes, Jan M. Deussing, Adam Kolarz, Alon Chen, Claudia Kühne, Michael W. Metzger, Mira Jakovcevski
Publikováno v:
Nature reviews / Neuroscience 21(6), 803-807 (2018). doi:10.1038/s41593-018-0151-z
Nat. Neurosci. 21, 803-807 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nat. Neurosci. 21, 803-807 (2018)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
The interplay between corticotropin-releasing hormone (CRH) and the dopaminergic system has predominantly been studied in addiction and reward, while CRH-dopamine interactions in anxiety are scarcely understood. We describe a new population of CRH-ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1cb6fb9c8125c204ce1bd4e894f0617