Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Elmer M. Price"'
Publikováno v:
Stem Cells and Development. 25:1109-1118
Individuals with neurodegenerative disorders or brain injury have few treatment options and it has been proposed that endogenous adult neural stem cells can be harnessed to repopulate dysfunctional nonneurogenic regions of the brain. We have accompli
Autofluorescent cells in rat brain can be convincing impostors in green fluorescent reporter studies
Publikováno v:
Journal of Neuroscience Methods. 197:48-55
Cell transplant and gene therapies are promising approaches to many disorders of the nervous system. In studies involving cell transplants to the brain or nervous system, expression of green fluorescent protein (GFP) is commonly used to label cells,
Autor:
Elmer M. Price, Alan S. Verkman, Darren B. Gruis, David C. A. Neville, Christine R. Rozanas, Raymond R. Townsend
Publikováno v:
Protein Science. 6:2436-2445
The cystic fibrosis transmembrane conductance regulator (CFTR) gene encodes an apical membrane Cl- channel regulated by protein phosphorylation. To identify cAMP-dependent protein kinase (PKA)-phosphorylated residues in full-length CFTR, immobilized
Publikováno v:
Journal of Applied Physiology. 105:1761-1771
Coronary arterioles from hypercholesterolemic swine display attenuated adenosine-mediated vasodilatation that is attributable to the elimination of voltage-dependent K+ (Kv) channel stimulation. For the present study, we tested the hypotheses that ex
Autor:
Elmer M. Price, Venkataseshu K. Ganjam, Duane H. Keisler, James R. Turk, Jennifer Casati, Ryan Jankord, M. Harold Laughlin, James C. Schadt
Publikováno v:
Endocrinology. 148:3758-3764
Inflammation contributes to disease development, and the neuroimmunoendocrine interface is a potential site of action for inflammatory products like IL-6 to affect health. Although plasma IL-6 can stimulate the activity of the hypothalamo-pituitary-a
Autor:
Tzyh Chang Hwang, Elmer M. Price, Nancy M. Walker, Darren B. Gruis, Lane L. Clarke, Lara R. Gawenis
Publikováno v:
American Journal of Physiology-Cell Physiology. 287:C192-C199
The major disease-causing mutation of the cystic fibrosis transmembrane conductance regulator (CFTR) is deletion of phenylalanine 508 (DeltaF508), which adversely affects processing and plasma membrane targeting of CFTR. Under conditions predicted to
Autor:
James R. Turk, Mark A. Thompson, Kyle K. Henderson, Christopher R. Woodman, James W. E. Rush, Elmer M. Price, M. Harold Laughlin
Publikováno v:
Journal of Applied Physiology. 96:1114-1126
We tested the hypothesis that exercise training (Ex) attenuates hypercholesterolemia-induced impairment of endothelium-dependent relaxation (EDR) in male porcine coronary arteries [left anterior descending coronary arteries (LAD)] by increasing nitri
Autor:
Kathryn E. Nichol, M. Harold Laughlin, Elmer M. Price, Judy M. Muller-Delp, Brian J. Philips, Edward M. Curran, Dennis B. Lubahn
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 285:H2150-H2157
Estrogen has been shown to increase endothelium-dependent vasodilation and expression of endothelial nitric oxide (NO) synthase (eNOS); however, the role of estrogen receptors in mediating estrogen effects on endothelial function remains to be elucid
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 284:H1307-H1312
The purpose of this study was to test the hypothesis that the content of endothelial nitric oxide synthase (eNOS) protein (eNOS protein/g total artery protein) increases with decreasing artery diameter in the coronary arterial tree. Content of eNOS p
Publikováno v:
Journal of Applied Physiology. 93:1685-1690
We tested the hypothesis that aging decreases endothelium-dependent vasodilation in feed arteries perfusing rat skeletal muscle. In addition, we tested the hypothesis that attenuated vasodilator responses are associated with decreased endothelial nit