Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Elmar Peschke"'
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 4, Pp 6981-7015 (2013)
The pineal hormone melatonin exerts its influence in the periphery through activation of two specific trans-membrane receptors: MT1 and MT2. Both isoforms are expressed in the islet of Langerhans and are involved in the modulation of insulin secretio
Externí odkaz:
https://doaj.org/article/51245dab0981403b97c0f88a45fe80ee
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2550
Cell culture of different pancreatic islet cell lines, like the murine α-cell line αTC1.9, the rat β-cell lines INS-1 and INS-1 832/13, and the human δ-cell line QGP-1, can serve as valuable cell models for the analysis of melatonin-dependent mod
Publikováno v:
Melatonin ISBN: 9781071625927
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4c1092b8ba5908ba188727951660e02
https://doi.org/10.1007/978-1-0716-2593-4_35
https://doi.org/10.1007/978-1-0716-2593-4_35
Publikováno v:
Journal of pineal research. 65(1)
Recent investigations of our group established that melatonin modulates hormone secretion of pancreatic islets via melatonin receptor types MT1 and MT2. Expression of MT1 and MT2 has been shown in mouse, rat, and human pancreatic islets as well as in
Publikováno v:
Journal of Pineal Research. 59:1-23
The pineal hormone melatonin influences insulin secretion, as well as glucagon and somatostatin secretion, both in vivo and in vitro. These effects are mediated by two specific, high-affinity, seven transmembrane, pertussis toxin-sensitive, Gi-protei
Publikováno v:
Cell and Tissue Research. 355:437-446
The neurohormone melatonin is synthesized by the pineal gland under the stimulation of norepinephrine (NE). Its synthesis is inhibited by acetylcholine (ACh) and by insulin. Type 2 diabetic Goto Kakizaki (GK) rats have higher insulin and lower melato
Publikováno v:
Hormone and Metabolic Research. 45:629-639
Several investigations have shown a relation between diabetes and alterations of the liver circadian clock. We investigated the diurnal expression of clock genes and clock-controlled genes (CCGs) in 3-hour intervals for a 24-h period in the livers of
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 4, Pp 6981-7015 (2013)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The pineal hormone melatonin exerts its influence in the periphery through activation of two specific trans-membrane receptors: MT1 and MT2. Both isoforms are expressed in the islet of Langerhans and are involved in the modulation of insulin secretio
Publikováno v:
Molecular and Cellular Endocrinology. 365:129-138
The retinoic-acid-related receptor family of orphan receptors (RORs) act as transcriptional activators or repressors. One of their functions involves integrated actions within circadian oscillators, particularly of the periphery. The present paper de
Publikováno v:
Journal of Pineal Research. 53:390-398
Melatonin has been shown to modulate glucose metabolism by influencing insulin secretion. Recent investigations have also indicated a regulatory function of melatonin on the pancreatic α-cells. The present in vitro and in vivo studies evaluated whet