Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Elmar Maier"'
Autor:
Elmar Maier, Richard Mott, Jörg D. Hoheisel, Hans Lehrach, Linda McCarthy, Zora Larin, Anthony P. Monaco, Andrei Grigoriev
The genome of the fission yeast, Schizosaccharomyces pombe, consists of some 14 million base pairs of DNA contained in three chromosomes. On account of its excellent genetics we used it as a test system for a strategy designed to map mammalian chromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e41415ed55784dfe7c2eb9972bf253e6
https://doi.org/10.1038/ng0792-273
https://doi.org/10.1038/ng0792-273
Autor:
Richard Mott, Elmar Maier, Hans Lehrach, Dean Nizetic, Leonard C. Schalkwyk, Andrei Grigoriev, Linda McCarthy, Jörg D. Hoheisel, Fiona Francis
Gridded on high density filters, a P1 genomic library of 17-fold coverage and a cosmid library of 8 genome equivalents, both made from S. pombe strain 972h-, were ordered by hybridizing genetic markers and individual clones from the two libraries. Ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb29d0e9c4d7177b876f11896403b8e6
https://doi.org/10.1016/0092-8674(93)90164-l
https://doi.org/10.1016/0092-8674(93)90164-l
Publikováno v:
Drug Discovery Today. 2:315-324
Array-based technologies are poised to revolutionize the application of genomic research to drug discovery. These highly parallel techniques are able to simultaneously analyze up to hundreds of thousands of elements, each arrayed at high density acro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39787d0a930bfbfcdc18b4e2b553c3c5
https://doi.org/10.1016/s1359-6446(97)01054-4
https://doi.org/10.1016/s1359-6446(97)01054-4
Autor:
Hans Lehrach, Elmar Maier
Publikováno v:
Chemie in unserer Zeit. 31:66-75
Automatische Bilddatenanalyse der Hybridisierung eines kurzen Oligonucleotids bekannter Sequenz auf eine gitterformig angeordnete DNA-Matrix. Die DNA-Matrix besteht aus insgesamt 57 600 unbekannten DNA-Sequenzen einer Genbibliothek. Die im Computer g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bf1f8ee80707e4045241386ea238ca2
https://doi.org/10.1002/ciuz.19970310204
https://doi.org/10.1002/ciuz.19970310204
Publikováno v:
Interdisciplinary Science Reviews. 22:37-44
A staggering amount of genetic information is contained within the DNA of complex organisms such as humans. Of these vast tracts of DNA code, only very small regions actually constitute the 'genes'; with the information ultimately translated into pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cccec3029f4101600e2c75a5134f872
https://doi.org/10.1179/isr.1997.22.1.37
https://doi.org/10.1179/isr.1997.22.1.37
Publikováno v:
Interdisciplinary Science Reviews. 22:37-44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d49127a90adb618ccb25f3c4278d18a5
https://doi.org/10.1179/030801897789765147
https://doi.org/10.1179/030801897789765147
Publikováno v:
Nucleic Acids Research. 21:1965-1974
A complete set of software tools to aid the physical mapping of a genome has been developed and successfully applied to the genomic mapping of the fission yeast Schizosaccharomyces pombe. Two approaches were used for ordering single-copy hybridisatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926272cf69fa083fe8b1ed0d59e55846
https://doi.org/10.1093/nar/21.8.1965
https://doi.org/10.1093/nar/21.8.1965
Autor:
Markus Kietzmann, Hans Lehrach, David Bancroft, Elmar Maier, Markus Kalkum, Holger Eickhoff, Igor Ivanov
Publikováno v:
Microsystem Technology: A Powerful Tool for Biomolecular Studies ISBN: 9783764357740
Each cell of a living organism contains the whole genetic information in form of DNA molecules. The size of the DNA from a single cell, or genome, of human beings is 3 × 109 nucleotide base pairs. Although the DNA information is usually identical in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acbf6e3f9222ea1f05a9c2516354875e
https://doi.org/10.1007/978-3-0348-8817-2_2
https://doi.org/10.1007/978-3-0348-8817-2_2
Autor:
Christopher T. Amemiya, Chaz Andre, Louis Bernier, Bruce Birren, Ken Dewar, Rainer Fislage, Martin Ganal, Caroline S. Gerrad, Richard Herrmann, Jrg D. Hoheisel, Adam Kuspa, Eric Lai, Richard W.F. Le Page, Jennifer S. Lee, Hans Lehrach, Roger C. Levesque, Gary W. Litman, William F. Loomis, Elmar Maier, Sara E. Melville, Michele Morgante, S.P. Morzaria, Richard Mott, Tatsuya Ota, Wayne Powell, J. Antoni Rafalski, Ute Römling, Nancy S. Shepherd, Scott V. Tingey, Burkhard Tümmler, Julie M. Vogel, Rainer Wenzel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6de4c9d4488d28b84dc6ae84f2c4b0c
https://doi.org/10.1016/b978-012101285-4/50000-x
https://doi.org/10.1016/b978-012101285-4/50000-x
Publikováno v:
Nonmammalian Genomic Analysis
This chapter discusses integrated genome mapping by hybridization techniques. Hybridization techniques provide the means for an efficient physical mapping. High-coverage clone libraries are generated and stored. It is found that whole libraries becom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d1f30c0161ac65306706acb0f9fc3e0
https://doi.org/10.1016/b978-012101285-4/50012-6
https://doi.org/10.1016/b978-012101285-4/50012-6