Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Elmar, Wahle"'
Posttranscriptional regulation of the maternal nanos mRNA is essential for the development of the anterior – posterior axis of the Drosophila embryo. The nanos RNA is regulated by the protein Smaug. Binding to Smaug recognition elements (SREs) in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9bc2df5cda3c2dc4b788cfe3117bfe
Autor:
Elmar Wahle, Uwe Kühn
Publikováno v:
eLS. :934-945
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70357b63666cc35dd7aaefc50d59c113
https://doi.org/10.1002/9780470015902.a0029243
https://doi.org/10.1002/9780470015902.a0029243
Autor:
Moritz Schmidt, Florian Kluge, Felix Sandmeir, Uwe Kühn, Peter Schäfer, Christian Tüting, Christian Ihling, Elena Conti, Elmar Wahle
Publikováno v:
Genes and Development
The 3′ ends of almost all eukaryotic mRNAs are generated in an essential two-step processing reaction: endonucleolytic cleavage of an extended precursor followed by the addition of a poly(A) tail. By reconstituting the reaction from overproduced an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c77d2c59bb2daaa81aef1389d6a7d66
Autor:
Felix Sandmeir, Christian Tüting, Uwe Kühn, Florian Kluge, Christian Ihling, Moritz Schmidt, Elena Conti, Elmar Wahle, Peter Schäfer
The 3’ ends of almost all eukaryotic mRNAs are generated in an essential two-step processing reaction, endonucleolytic cleavage of an extended precursor followed by the addition of a poly(A) tail. By reconstituting the reaction from overproduced an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::913ade3f6a47d8642dbcec7b0a18e8bd
https://doi.org/10.1101/2021.11.02.466878
https://doi.org/10.1101/2021.11.02.466878
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90915 (2014)
5'-nucleotidases catalyze the hydrolytic dephosphorylation of nucleoside monophosphates. As catabolic enzymes they contribute significantly to the regulation of cellular nucleotide levels; misregulation of nucleotide metabolism and nucleotidase defic
Externí odkaz:
https://doaj.org/article/6c30d2058f384b598ac7d067178c28fe
Publikováno v:
RNA, 26 (5)
RNA
RNA
Functions of eukaryotic mRNAs are characterized by intramolecular interactions between their ends. We have addressed the question whether 5′ and 3′ ends meet by diffusion-controlled encounter “through solution” or by a mechanism involving the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9a8d7f74248dd4444c09d080f3080a
Autor:
Timothy C. H. Low, Najeeb U. Siddiqui, Stephane Angers, Sichun Lin, Craig A. Smibert, Sarah Kabelitz, Meera Gupta, Martin Wühr, Christian Ihling, Elmar Wahle, Matthew H. K. Cheng, Howard D. Lipshitz, Eyan Yeung, Filip Pekovic, Wen Xi Cao, Christiane Rammelt
Publikováno v:
Cell reports
SUMMARY In animal embryos, the maternal-to-zygotic transition (MZT) hands developmental control from maternal to zygotic gene products. We show that the maternal proteome represents more than half of the protein-coding capacity of Drosophila melanoga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dde1d3ac5915663355dbeed80e070c94
https://doi.org/10.1101/862490
https://doi.org/10.1101/862490
Autor:
Martine Simonelig, Stéphanie Pierson, Nagraj Sambrani, Elmar Wahle, Christiane Rammelt, Claudia Temme, Michael Götze, Christian Ihling, Andrea Sinz, Jeremy Dufourt
Publikováno v:
RNA
RNA, 2017, 23 (10), pp.1552-1568. ⟨10.1261/rna.062208.117⟩
RNA, Cold Spring Harbor Laboratory Press, 2017, 23 (10), pp.1552-1568. ⟨10.1261/rna.062208.117⟩
RNA, 2017, 23 (10), pp.1552-1568. ⟨10.1261/rna.062208.117⟩
RNA, Cold Spring Harbor Laboratory Press, 2017, 23 (10), pp.1552-1568. ⟨10.1261/rna.062208.117⟩
Translational repression of maternal mRNAs is an essential regulatory mechanism during early embryonic development. Repression of theDrosophila nanosmRNA, required for the formation of the anterior-posterior body axis, depends on the protein Smaug bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256aff44cf40487ec1d6b407282e95fc
https://doi.org/10.1261/rna.062208.117
https://doi.org/10.1261/rna.062208.117
Oligoadenylation of 3′ decay intermediates promotes cytoplasmic mRNA degradation in Drosophila cells
Autor:
Christiane Harnisch, Heinz Himmelbauer, Elmar Wahle, Juliane C. Dohm, Michael Götze, Simona Cuzic-Feltens
Publikováno v:
RNA. 22:428-442
Post-transcriptional 3′ end addition of nucleotides is important in a variety of RNA decay pathways. We have examined the 3′ end addition of nucleotides during the decay of the Hsp70 mRNA and a corresponding reporter RNA in Drosophila S2 cells by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d88a744f3911fdf76d7e989a1c9d533
https://doi.org/10.1261/rna.053942.115
https://doi.org/10.1261/rna.053942.115
Autor:
Thomas Treiber, Andrea Sinz, Nora Treiber, Elmar Wahle, Uwe Kühn, Anne Graber, Christian Tüting, Lars Schönemann, Peter Schaefer, Christian Ihling, Gunter Meister, Walter Keller
Cleavage factor II (CF II) is a poorly characterized component of the multi-protein complex catalyzing 3’ cleavage and polyadenylation of mammalian mRNA precursors. We have reconstituted CF II as a heterodimer of hPcf11 and hClp1. The heterodimer i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cfec9bd67627b07e5376570cf00dd65
https://doi.org/10.1101/366336
https://doi.org/10.1101/366336