Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Elmar, Jaeckel"'
Autor:
Jeffrey To, Soumita Ghosh, Xun Zhao, Elisa Pasini, Sandra Fischer, Gonzalo Sapisochin, Anand Ghanekar, Elmar Jaeckel, Mamatha Bhat
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-12 (2024)
Abstract Background Liver transplantation (LT) is offered as a cure for Hepatocellular carcinoma (HCC), however 15–20% develop recurrence post-transplant which tends to be aggressive. In this study, we examined the transcriptome profiles of patient
Externí odkaz:
https://doaj.org/article/6bd3bd44dd4b43f0bb30d758de803db7
Autor:
Nadja Seltrecht, Matthias Hardtke-Wolenski, Konstantinos Iordanidis, Danny Jonigk, Melanie Galla, Axel Schambach, Laura Elisa Buitrago-Molina, Heiner Wedemeyer, Fatih Noyan, Elmar Jaeckel
Publikováno v:
Cells, Vol 13, Iss 14, p 1216 (2024)
Background: Solid organ transplantation is hindered by immune-mediated chronic graft dysfunction and the side effects of immunosuppressive therapy. Regulatory T cells (Tregs) are crucial for modulating immune responses post-transplantation; however,
Externí odkaz:
https://doaj.org/article/4429a14562044937a921119004b57d0a
Autor:
Alejandro Campos-Murguia, Nicole Henjes, Stephanie Loges, Heiner Wedemeyer, Elmar Jaeckel, Richard Taubert, Bastian Engel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Autoantibodies are the diagnostic hallmark of autoimmune liver diseases. Indirect immunofluorescence (IFT) is the reference method for the detection of anti-mitochondrial antibodies (AMA) and anti-liver kidney microsomal type-1 (anti-LKM1) a
Externí odkaz:
https://doaj.org/article/8d9ac42811f34a7b95b746a234a1db07
Autor:
Fakhar Ali Qazi Arisar, Rhea Varghese, Shiyi Chen, Wei Xu, Markus Selzner, Ian McGilvray, Blayne Sayed, Trevor Reichman, Chaya Shwaartz, Mark Cattral, Anand Ghanekar, Gonzalo Sapisochin, Elmar Jaeckel, Cynthia Tsien, Nazia Selzner, Leslie Lilly, Mamatha Bhat
Publikováno v:
Annals of Hepatology, Vol 29, Iss 1, Pp 101168- (2024)
Introduction and Objectives: Recurrent cirrhosis complicates 10-30% of Liver transplants (LT) and can lead to consideration for re-transplantation. We evaluated the trajectories of relisted versus primary listed patients on the waitlist using a compe
Externí odkaz:
https://doaj.org/article/7f9ac428ce9b43c1936117868c3d8bc2
Autor:
Bastian Engel, Ida Falk Villesen, Mette Juul Fisker Nielsen, Morten Karsdal, Richard Taubert, Elmar Jaeckel, Diana Julie Leeming
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Detecting patients with early post-transplant fibrosis after liver transplantation (LT) is very important. Non-invasive tests are needed to avoid liver biopsies. We aimed to detect fibrosis in liver transplant recipients (LTR) using extracel
Externí odkaz:
https://doaj.org/article/76e18119c67b4d6e9d61a2f4a352f303
Autor:
Emily A. Bosselmann, Bastian Engel, Björn Hartleben, Heiner Wedemeyer, Elmar Jaeckel, Benjamin Maasoumy, Andrej Potthoff, Steffen Zender, Richard Taubert
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
BackgroundLiver stiffness measurements (LSMs) have proven useful for non-invasive detection of fibrosis. Previous studies of LSMs after transplantation were performed in cohorts dominated by hepatitis C reinfections and indication biopsies for the ev
Externí odkaz:
https://doaj.org/article/eddb67b9d3de4bd5a5a7b367d41aa18d
Autor:
Madhumitha Rabindranath, HBSc, Rita Zaya, MD, Khairunnadiya Prayitno, PhD, Ani Orchanian-Cheff, MISt, Keyur Patel, MD, PhD, Elmar Jaeckel, MD, Mamatha Bhat, MD, PhD
Publikováno v:
Transplantation Direct, Vol 9, Iss 11, p e1547 (2023)
Despite advances in posttransplant care, long-term outcomes for liver transplant recipients remain unchanged. Approximately 25% of recipients will advance to graft cirrhosis and require retransplantation. Graft fibrosis progresses in the context of d
Externí odkaz:
https://doaj.org/article/e16bf567304e420db4ef3b2d2763957e
Publikováno v:
BMC Gastroenterology, Vol 22, Iss 1, Pp 1-4 (2022)
Abstract In the January 2022 issue of BMC Gastroenterology, Chen et al. report an association between serum ferritin levels and the presence of advanced liver fibrosis in patients with treatment-naïve autoimmune hepatitis (AIH). The odds ratio for f
Externí odkaz:
https://doaj.org/article/3560f8e21fdd4b68a5559c2c596a5b39
Autor:
Janine Dywicki, Laura Elisa Buitrago-Molina, Fatih Noyan, Jerome Schlue, Konstantinos Iordanidis, Michael P. Manns, Heiner Wedemeyer, Elmar Jaeckel, Matthias Hardtke-Wolenski
Publikováno v:
European Journal of Medical Research, Vol 27, Iss 1, Pp 1-8 (2022)
Abstract Autoimmune hepatitis (AIH) is a chronic immune-mediated inflammatory liver disease. It is known that AIH originates not from the spleen but from the liver itself. Nonetheless, most details of the etiology and pathophysiology are unknown. We
Externí odkaz:
https://doaj.org/article/b06c23f9432545069705c91450ad0e1a
Autor:
Fernanda Onofrio, Katina Zheng, Cherry Xu, Shiyi Chen, Wei Xu, Mary Vyas, Katie Bingham, Keyur Patel, Leslie Lilly, Mark Cattral, Nazia Selzner, Elmar Jaeckel, Cynthia Tsien, Aliya Gulamhusein, Gideon M. Hirschfield, Mamatha Bhat
Publikováno v:
Hepatology Communications, Vol 7, Iss 8 (2023)
Background:. Liver transplantation (LT) is frequently lifesaving for people living with primary sclerosing cholangitis (PSC). However, patients are waitlisted for LT according to the model for end-stage liver disease-sodium (MELD-Na) score, which may
Externí odkaz:
https://doaj.org/article/2b11aa1f87db488d9f804a95cd17c0e3