Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Elly van Koolwijk"'
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Distribution of mucosal PD-1 expressing T cells in patients with colitis of different etiologies
Autor: Marcel J M Groenen, Jan Willem Leeuwis, Ellen G van Lochem, Carolijn Smids, Peter J. Wahab, Elly van Koolwijk, Britt Roosenboom, Carmen S Horjus Talabur Horje
Publikováno v: Scandinavian journal of gastroenterology. 56(6)
Immunotherapy, targeting programmed death-1 (PD-1) enhances antitumor T-cell activity in patients with malignancies. Blocking PD-1 or its ligand may lead to fulminant colitis as serious adverse event in these patients. Since little is known of the pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7d971ee7490dffa5e8b5f7039cd722
https://pubmed.ncbi.nlm.nih.gov/33779456
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3
Intestinal CD103+CD4+ and CD103+CD8+ T-Cell Subsets in the Gut of Inflammatory Bowel Disease Patients at Diagnosis and During Follow-up
Autor: Carmen S Horjus Talabur Horje, Britt Roosenboom, Marcel J M Groenen, Elly van Koolwijk, Carolijn Smids, Peter J. Wahab, Ellen G van Lochem
Publikováno v: Inflamm Bowel Dis
Background The integrin CD103 is proposed to be a potential therapeutical target in inflammatory bowel disease (IBD), as it can form a heterodimeric integrin with β7 (Etrolizumab, anti-β7 integrin) on epithelial T cells. Therefore, we aimed to stud
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48474f492631b69d858553a34f86fca4
https://pubmed.ncbi.nlm.nih.gov/31904085
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4
The value of serum antibodies in differentiating inflammatory bowel disease, predicting disease activity and disease course in the newly diagnosed patient
Autor: Ellen G van Lochem, Peter J. Wahab, Elly van Koolwijk, Carolijn Smids, Marcel J M Groenen, Carmen S Horjus Talabur Horje
Publikováno v: Scandinavian journal of gastroenterology. 52(10)
Data on serum antibodies in untreated adult inflammatory bowel disease (IBD) patients at diagnosis are scarcely available, and results on the stability of antibody presence over time are inconsistent. Our aim was to investigate antibodies in newly di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0c980b37c8277b5b5c1942cae41ce6
https://pubmed.ncbi.nlm.nih.gov/28661185
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5
Intestinal T Cell Profiling in Inflammatory Bowel Disease: Linking T Cell Subsets to Disease Activity and Disease Course
Autor: Elly van Koolwijk, Julia Drylewicz, Marcel J M Groenen, Peter J. Wahab, Carmen S Horjus Talabur Horje, Britt Roosenboom, Carolijn Smids, Ellen G van Lochem
Publikováno v: Journal of Crohn's and Colitis, 12(4), 465. Elsevier
Introduction A dysregulated intestinal T cell response is presumed in patients with inflammatory bowel disease [IBD]. In this longitudinal study, we investigated the changes in intestinal T lymphocyte subsets in IBD at first presentation and over tim
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a689585eace37aec8c6afea87030e8
https://pubmed.ncbi.nlm.nih.gov/29211912
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6
A pilot study of CXCL8 levels in crystal proven gout patients during allopurinol treatment and their association with cardiovascular disease
Autor: Laura B.E. Kienhorst, Ellen G van Lochem, Hein J.E.M. Janssens, Matthijs Janssen, Timothy R D J Radstake, Elly van Koolwijk, Piet L. C. M. van Riel, Johannes W G Jacobs
Publikováno v: Joint Bone Spine, 84, 6, pp. 709-713
Joint Bone Spine, 84, 709-713
Item does not contain fulltext OBJECTIVES: Gout is associated with cardiovascular diseases, and systemic inflammation has a role in this. CXCL8 (interleukin-8) levels were increased in synovial fluid of gout patients, and in serum in gout patients ir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4e4e00191004031ae43c55dee04c5c
https://hdl.handle.net/2066/181709
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8
Gout Is a Chronic Inflammatory Disease in Which High Levels of Interleukin-8 (CXCL8), Myeloid-Related Protein 8/Myeloid-Related Protein 14 Complex, and an Altered Proteome Are Associated With Diabetes Mellitus and Cardiovascular Disease
Autor: Waander L. van Heerde, Dirk Holzinger, Lisa K. Stamp, Jacqueline de Graaf, Matthijs Janssen, Elly van Koolwijk, Hein J.E.M. Janssens, Jasper C A Broen, Timothy R D J Radstake, Laura B.E. Kienhorst, Johannes Roth, Nicola Dalbeth, A. Loof, Sita H. Vermeulen, Amanda Phipps-Green, Ellen G van Lochem, Wietske Kievit, Marilyn E. Merriman, Tony R. Merriman
Publikováno v: Arthritis & Rheumatology, 67, 3303-13
Arthritis & Rheumatology, 67, 12, pp. 3303-13
Arthritis & Rheumatology, 67(12), 3303. John Wiley and Sons Ltd
Contains fulltext : 152269.pdf (Publisher’s version ) (Closed access) OBJECTIVE: The frequent association of gout with metabolic syndrome and cardiovascular disease (CVD) suggests that it has a systemic component. Our objective was to study whether
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163524f86adcd7ad105d707ffdedaf58
http://hdl.handle.net/2066/152269
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9
Naive T cells in the gut of newly diagnosed, untreated adult patients with inflammatory bowel disease
Autor: Marcel J M Groenen, Carmen S Horjus Talabur Horje, Sabine Middendorp, Lian Roovers, Ellen G van Lochem, Elly van Koolwijk, Peter J. Wahab
Publikováno v: Inflammatory bowel diseases. 20(11)
Background The phenotype of the T-cell subpopulations and their related cytokine networks in the gastrointestinal mucosa of patients with inflammatory bowel disease can potentially be used as a predictive value for clinical course and response to the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f0ab0fcfcdd6d2ab2036e26916e2d3
https://pubmed.ncbi.nlm.nih.gov/25248006
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