Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Elly Marcq"'
Autor:
Astrid Van den Eynde, Laura Gehrcken, Tias Verhezen, Ho Wa Lau, Christophe Hermans, Hilde Lambrechts, Tal Flieswasser, Delphine Quatannens, Gils Roex, Karen Zwaenepoel, Elly Marcq, Philippe Joye, Edgar Cardenas De La Hoz, Christophe Deben, Alessia Gasparini, Pierre Montay-Gruel, Maxim Le Compte, Eva Lion, Filip Lardon, Steven Van Laere, Vasiliki Siozopoulou, Diana Campillo-Davo, Jorrit De Waele, Patrick Pauwels, Julie Jacobs, Evelien Smits, Jonas R. M. Van Audenaerde
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-19 (2024)
Abstract Background It remains challenging to obtain positive outcomes with chimeric antigen receptor (CAR)-engineered cell therapies in solid malignancies, like colorectal cancer (CRC) and pancreatic ductal adenocarcinoma (PDAC). A major obstacle is
Externí odkaz:
https://doaj.org/article/8761eb0063d942beb968b458b3b522ca
Autor:
Scott A. Fisher, Kimberley Patrick, Tracy Hoang, Elly Marcq, Kiarash Behrouzfar, Sylvia Young, Timothy J. Miller, Bruce W. S. Robinson, Raphael Bueno, Anna K. Nowak, W. Joost Lesterhuis, Grant Morahan, Richard A. Lake
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Objectives: This study combines two innovative mouse models in a major gene discovery project to assess the influence of host genetics on asbestos related disease (ARD). Conventional genetics studies provided evidence that some susceptibility to meso
Externí odkaz:
https://doaj.org/article/3d44dba5e34544bab7bb7980e494ea5c
Autor:
Abraham Lin, Joey De Backer, Delphine Quatannens, Bart Cuypers, Hanne Verswyvel, Edgar Cardenas De La Hoz, Bart Ribbens, Vasiliki Siozopoulou, Jonas Van Audenaerde, Elly Marcq, Filip Lardon, Kris Laukens, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 3, Pp n/a-n/a (2022)
Abstract Melanoma remains a deadly cancer despite significant advances in immune checkpoint blockade and targeted therapies. The incidence of melanoma is also growing worldwide, which highlights the need for novel treatment options and strategic comb
Externí odkaz:
https://doaj.org/article/17eb6880cebd4836b899d3e52353311c
Autor:
Laurie Freire Boullosa, Jinthe Van Loenhout, Tal Flieswasser, Christophe Hermans, Céline Merlin, Ho Wa Lau, Elly Marcq, Marlies Verschuuren, Winnok H. De Vos, Filip Lardon, Evelien L. J. Smits, Christophe Deben
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 667 (2023)
Auranofin (AF) is a potent, off-patent thioredoxin reductase (TrxR) inhibitor that efficiently targets cancer via reactive oxygen species (ROS)- and DNA damage-mediated cell death. The goal of this study is to enhance the efficacy of AF as a cancer t
Externí odkaz:
https://doaj.org/article/7a155ad553444ac0bd4721cceca973cd
Autor:
Vasiliki Siozopoulou, Elly Marcq, Koen De Winne, Koen Norga, Gertjan Schmitz, Valerie Duwel, Philippe Delvenne, Evelien Smits, Patrick Pauwels
Publikováno v:
Pathology and Oncology Research, Vol 28 (2022)
Targeting molecular alterations has been proven to be an inflecting point in tumor treatment. Especially in recent years, inhibitors that target the tyrosine receptor kinase show excellent response rates and durable effects in all kind of tumors that
Externí odkaz:
https://doaj.org/article/0c194190c2a14a9a8d6fd0293ef53a92
Autor:
Eline Janssens, Zoë Mol, Lore Vandermeersch, Sabrina Lagniau, Karim Y. Vermaelen, Jan P. van Meerbeeck, Christophe Walgraeve, Elly Marcq, Kevin Lamote
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionMalignant pleural mesothelioma (MPM) is a lethal cancer for which early-stage diagnosis remains a major challenge. Volatile organic compounds (VOCs) in breath proved to be potential biomarkers for MPM diagnosis, but translational studies
Externí odkaz:
https://doaj.org/article/e7a073155e374b71ae6b2bfc22b3bc5b
Autor:
Laurie Freire Boullosa, Jinthe Van Loenhout, Christophe Hermans, Ho Wa Lau, Céline Merlin, Elly Marcq, Farnaz Sedigheh Takhsha, Wim Martinet, Guido R. Y. De Meyer, Filip Lardon, Evelien L. J. Smits, Christophe Deben
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2761 (2022)
The antineoplastic activity of the thioredoxin reductase 1 (TrxR) inhibitor, auranofin (AF), has already been investigated in various cancer mouse models as a single drug, or in combination with other molecules. However, there are inconsistencies in
Externí odkaz:
https://doaj.org/article/bf1c62dc6aa04eb0a23e72cc58e42727
Autor:
Scott A. Fisher, Carolyn J. Peddle-McIntyre, Kimberley Burton, Robert U. Newton, Elly Marcq, Richard A. Lake, Anna K. Nowak
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-8 (2020)
Abstract Objective There is substantial evidence that exercise can safely reduce the risk of cancer and improve survival in different human cancer populations. Long latency periods associated with carcinogen–induced cancers like asbestos induced me
Externí odkaz:
https://doaj.org/article/d11f9550bc764e9584fb4a8af38d4896
Autor:
Eline Janssens, Eline Schillebeeckx, Kathleen Zwijsen, Jo Raskin, Joris Van Cleemput, Veerle F. Surmont, Kristiaan Nackaerts, Elly Marcq, Jan P. van Meerbeeck, Kevin Lamote
Publikováno v:
Cancers, Vol 14, Iss 13, p 3182 (2022)
During the past decade, volatile organic compounds (VOCs) in exhaled breath have emerged as promising biomarkers for malignant pleural mesothelioma (MPM). However, as these biomarkers lack external validation, no breath test for MPM has been implemen
Externí odkaz:
https://doaj.org/article/290450d99083474eb4b9653354e72883
Autor:
Sophie Rovers, Annelies Janssens, Jo Raskin, Patrick Pauwels, Jan P. van Meerbeeck, Evelien Smits, Elly Marcq
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 673 (2022)
Malignant pleural mesothelioma (MPM) is a fatal cancer type that affects the membranes lining the lungs, and is causally associated with asbestos exposure. Until recently, the first-line treatment consisted of a combination of chemotherapeutics that
Externí odkaz:
https://doaj.org/article/2ab04385e8c04a289f2f60a2e8573ba3