Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Elly M Sweet"'
Publikováno v:
PLoS Genetics, Vol 6, Iss 9, p e1001133 (2010)
Preplacodal ectoderm arises near the end of gastrulation as a narrow band of cells surrounding the anterior neural plate. This domain later resolves into discrete cranial placodes that, together with neural crest, produce paired sensory structures of
Externí odkaz:
https://doaj.org/article/ae646fcb4d4249579850f7180307f1cf
Publikováno v:
Developmental Biology. 435:73-83
Formation of neural and sensory progenitors in the inner ear requires Sox2 in mammals, and in other species is thought to rely on both Sox2 and Sox3. How Sox2 and/or Sox3 promote different fates is poorly understood. Our mutant analysis in zebrafish
Publikováno v:
Evolution & Development. 15:426-441
The processes that direct skull remodeling are of interest to both human-oriented studies of cranial dysplasia and evolutionary studies of skull divergence. There is increasing awareness that these two fields can be mutually informative when natural
Publikováno v:
Developmental Biology. 358:113-121
Atoh1 is required for differentiation of sensory hair cells in the vertebrate inner ear. Moreover, misexpression of Atoh1 is sufficient to establish ectopic sensory epithelia, making Atoh1 a good candidate for gene therapy to restore hearing. However
Autor:
Toshiro Shigaki, Bruce B. Riley, Hui Mei, Colin W. MacDiarmid, Murli Manohar, Andrew Franklin, Elly M. Sweet, Kendal D. Hirschi
Publikováno v:
Biochemistry. 49:6557-6566
CAtion/H(+) eXchangers (CAXs) are integral membrane proteins that transport Ca(2+) or other cations by exchange with protons. While several yeast and plant CAX proteins have been characterized, no functional analysis of a vertebrate CAX homologue has
Autor:
Adrienne Evans, Bruce B. Riley, Karen N. McFarland, Elly M. Sweet, Rachel M. Warga, Rebecca Heck, Donald A. Kane
Publikováno v:
Developmental Dynamics. 239:828-843
We have characterized mutations in the early arrest gene, harpy (hrp), and show that they introduce premature stops in the coding region of early mitotic inhibitor1 (Rca1/emi1). In harpy mutants, cells stop dividing during early gastrulation. Lineage
Publikováno v:
Development. 134:295-305
Hair cells of the inner ear develop from an equivalence group marked by expression of the proneural gene Atoh1 . In mouse, Atoh1 is necessary for hair cell differentiation, but its role in specifying the equivalence group (proneural function) has bee
Publikováno v:
Evolutiondevelopment. 15(6)
The processes that direct skull remodeling are of interest to both human-oriented studies of cranial dysplasia and evolutionary studies of skull divergence. There is increasing awareness that these two fields can be mutually informative when natural
Publikováno v:
Developmental biology. 338(2)
Sox2 has been variously implicated in maintenance of pluripotent stem cells or, alternatively, early stages of cell differentiation, depending on context. In the developing inner ear, Sox2 initially marks all cells in the nascent sensory epithelium a