Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ellora Hui Zhen Chua"'
Autor:
Jay B. Lusk, Ellora Hui Zhen Chua, Prameet Kaur, Isabelle Chiao Han Sung, Wen Kin Lim, Vanessa Yuk Man Lam, Nathan Harmston, Nicholas S. Tolwinski
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Proper embryonic development requires directional axes to pattern cells into embryonic structures. In Drosophila, spatially discrete expression of transcription factors determines the anterior to posterior organization of the early embryo, w
Externí odkaz:
https://doaj.org/article/dfb761956de44fe5ad80f4623742e7b2
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Mutational signatures are characteristic patterns of mutations generated by exogenous mutagens or by endogenous mutational processes. Mutational signatures are important for research into DNA damage and repair, aging, cancer biology, genetic
Externí odkaz:
https://doaj.org/article/1a915049c41a4a2fa8366715e23d7dca
Publikováno v:
Biology Open, Vol 11, Iss 4 (2022)
The expression of a large number of genes is regulated by regulatory elements that are located far away from their promoters. Identifying which gene is the target of a specific regulatory element or is affected by a non-coding mutation is often accom
Externí odkaz:
https://doaj.org/article/976d3e3088434d168bd16ad5f6c8854f
Autor:
Prameet Kaur, Ellora Hui Zhen Chua, Wen Kin Lim, Jiarui Liu, Nathan Harmston, Nicholas S. Tolwinski
Publikováno v:
Cells, Vol 11, Iss 2, p 281 (2022)
Patients with Alzheimer’s disease suffer from a decrease in brain mass and a prevalence of amyloid-β plaques. These plaques are thought to play a role in disease progression, but their exact role is not entirely established. We developed an optoge
Externí odkaz:
https://doaj.org/article/8b64a16f5e3e4962a0df8a123b0e5647
Autor:
Prameet Kaur, Agimaa Otgonbaatar, Anupriya Ramamoorthy, Ellora Hui Zhen Chua, Nathan Harmston, Jan Gruber, Nicholas S. Tolwinski
Publikováno v:
Aging. 14(20)
Why biological age is a major risk factor for many of the most important human diseases remains mysterious. We know that as organisms age, stem cell pools are exhausted while senescent cells progressively accumulate. Independently, induction of pluri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99d3a4a3f25cdccc7684313fef904f88
https://pubmed.ncbi.nlm.nih.gov/36287172
https://pubmed.ncbi.nlm.nih.gov/36287172
Autor:
Jay B. Lusk, Ellora Hui Zhen Chua, Prameet Kaur, Isabelle Chiao Han Sung, Wen Kin Lim, Vanessa Yuk Man Lam, Nathan Harmston, Nicholas S. Tolwinski
Publikováno v:
Scientific reports. 12(1)
Proper embryonic development requires directional axes to pattern cells into embryonic structures. In Drosophila, spatially discrete expression of transcription factors determines the anterior to posterior organization of the early embryo, while the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d038db985208c37ce93eb31e8c20b4e
https://pubmed.ncbi.nlm.nih.gov/35538124
https://pubmed.ncbi.nlm.nih.gov/35538124
Previously, we established an optogenetic model to induce Amyloid-β intracellular oligomerization to model distinct disease etiologies (Limet al. 2020). Here we examine the effect of Wnt signaling on Amyloid in this model. We observe that Wnt activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::041018e50aea0bbc29ef4e0a8eb71599
https://doi.org/10.1101/2021.09.06.459094
https://doi.org/10.1101/2021.09.06.459094
Autor:
Nicholas S. Tolwinski, Wen Kin Lim, Nathan Harmston, Vanessa Yuk Man Lam, Jay B Lusk, Prameet Kaur, Ellora Hui Zhen Chua, Isabelle Chiao Han Sung
Proper embryonic development requires directional axes to pattern cells into embryonic structures. In Drosophila, spatially discrete expression of transcription factors determines the anterior to posterior organization of the early embryo, while the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9744a9990fd4efa721c4844850f5f3d
https://doi.org/10.1101/2021.07.29.454294
https://doi.org/10.1101/2021.07.29.454294