Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors Based on the Pyridyl-Pyridazine Moiety for the Potential Treatment of Alzheimer's Disease.

Autor: Elsawalhy M; Department of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt., Abdel-Rahman AA; Department of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt., Basiony EA; Department of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt., Ellithy SA; Department of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt., Hassan AA; Department of Chemistry, Faculty of Science, Suez University, Suez 43221, Egypt., Abou-Amra ES; Department of Chemistry, Organic Chemistry, Faculty of Science (Girls), Al-Azhar University, Cairo 11754, Egypt., Ismail A; Department of Chemistry, Faculty of Science, Menofia University, Shbien El-Kom 32511, Egypt., Almehizia AA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia., Al-Omar MA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia., Naglah AM; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia., Hassan NA; Synthetic Unit, Department of Photochemistry, Chemical Industries Research Institute, National Research Centre, Cairo 12622, Egypt.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2024 Oct 21; Vol. 17 (10). Date of Electronic Publication: 2024 Oct 21.