Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Ellis R Levin"'
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95987 (2014)
The effects of 17-β-estradiol in osteoblasts are primarily mediated by the nuclear transcription factors, estrogen receptor (ER)α and ERβ. ERs function through three general modes of action: DNA-binding dependent through estrogen response elements
Externí odkaz:
https://doaj.org/article/b43d98d6984f422b9b45061f4813e560
Autor:
Sanoara Mazid, Elizabeth M. Waters, Chloe Lopez-Lee, Renata Poultan Kamakura, Batsheva R. Rubin, Ellis R. Levin, Bruce S. McEwen, Teresa A. Milner
Publikováno v:
Biology, Vol 12, Iss 4, p 632 (2023)
Estrogens via estrogen receptor alpha (ERα) genomic and nongenomic signaling can influence plasticity processes in numerous brain regions. Using mice that express nuclear only ERα (NOER) or membrane only ERα (MOER), this study examined the effect
Externí odkaz:
https://doaj.org/article/9084af1be21841c9b822cedb159ae1fa
Autor:
Ellis R. Levin
Estrogen receptors at the plasma membrane and cytoplasm have been difficult to detect in breast cancer specimens. New imaging approaches are needed to determine the percentage of cancers expressing extranuclear estrogen receptors and their impact on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43ef75af7472e6c9e7a3f3fe00c61eee
https://doi.org/10.1158/1078-0432.c.6521151
https://doi.org/10.1158/1078-0432.c.6521151
Autor:
Joyce M. Slingerland, Gordon B. Mills, Yiling Lu, Roel G.W. Verhaak, Ji-Yeon Yang, Tan A. Ince, Xiang-Xi Xu, Diana Azzam, Brian Rabinovich, Isildinha M. Reis, Ellis R. Levin, Ali Pedram, Thiago da Silva, Candace A. Gilbert, Wendy Ullmer, Jun Sun, Pedro Hevia-Paez, Fiona Simpkins
PDF file, 46K, List of genes which have one or more ERE in the promoter upstream 10kb region in 111 genes that overlapped in the High ERα and High p416Src groups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7e32693b853855f4eb0925ec381ca3
https://doi.org/10.1158/1078-0432.22446114
https://doi.org/10.1158/1078-0432.22446114
Autor:
Joyce M. Slingerland, Gordon B. Mills, Yiling Lu, Roel G.W. Verhaak, Ji-Yeon Yang, Tan A. Ince, Xiang-Xi Xu, Diana Azzam, Brian Rabinovich, Isildinha M. Reis, Ellis R. Levin, Ali Pedram, Thiago da Silva, Candace A. Gilbert, Wendy Ullmer, Jun Sun, Pedro Hevia-Paez, Fiona Simpkins
Purpose: More effective, less toxic treatments for recurrent ovarian cancer are needed. Although more than 60% of ovarian cancers express the estrogen receptor (ER), ER-targeted drugs have been disappointing due to drug resistance. In other estrogen-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c473c1c95e7a06f5c9f6eff942571d
https://doi.org/10.1158/1078-0432.c.6520653
https://doi.org/10.1158/1078-0432.c.6520653
Autor:
Ellis R. Levin
Related Article from Elusive Extranuclear Estrogen Receptors in Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75efe9540f8f33988744ead67155f31
https://doi.org/10.1158/1078-0432.22447635.v1
https://doi.org/10.1158/1078-0432.22447635.v1
Publikováno v:
Endocrine Reviews. 43:720-742
Rapid effects of steroid hormones were discovered in the early 1950s, but the subject was dominated in the 1970s by discoveries of estradiol and progesterone stimulating protein synthesis. This led to the paradigm that steroid hormones regulate growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33e420e29172cca6b6b3f0f1c3fb5e4c
https://doi.org/10.1210/endrev/bnab041
https://doi.org/10.1210/endrev/bnab041
Autor:
Amrita Ahluwalia, Neil Hoa, Debbie Moreira, Daniel Aziz, Karanvir Singh, Khushin N Patel, Ellis R Levin
Publikováno v:
Endocrinology. 164(2)
Estrogen acting through estrogen receptor β (ERβ) has been shown to oppose the stimulation of cardiac myocytes and cardiac fibroblasts that results in cardiac hypertrophy and fibrosis. Previous work has implicated signal transduction from ERβ as b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46262dedadf87aed5b31127106fbf5c1
https://pubmed.ncbi.nlm.nih.gov/36461668
https://pubmed.ncbi.nlm.nih.gov/36461668
Autor:
Ellis R. Levin, Theresa I. Medrano, Jiude Mao, Paul S. Cooke, Cheryl S. Rosenfeld, Paul D. Caldo, Ana M Mesa, Madison T. Ortega, Manjunatha K. Nanjappa, Jessica A. Kinkade
Publikováno v:
Biol Reprod
Biology of reproduction, vol 101, iss 2
Biology of reproduction, vol 101, iss 2
Both membrane and nuclear fractions of estrogen receptor 1 (ESR1) mediate 17β-estradiol (E2) actions. Mice expressing nuclear (n)ESR1 but lacking membrane (m)ESR1 (nuclear-only estrogen receptor 1 [NOER] mice) show reduced E2 responsivity and reprod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acb6281ba6c9d53b4e0efa8b51a10f4
https://doi.org/10.1093/biolre/ioz090
https://doi.org/10.1093/biolre/ioz090
Autor:
Cristal M. Hill, Ellis R. Levin, Laurel A. Coons, Diana C. Albarado, Guy Fagherazzi, Kenneth S. Korach, John J. Lefante, Camille Allard, Franck Mauvais-Jarvis, Fabrice Bonnet, Christopher D. Morrison, Beibei Xu
Publikováno v:
Molecular Metabolism, Vol 22, Iss, Pp 62-70 (2019)
Molecular Metabolism
Molecular Metabolism
Objective The endogenous estrogen 17β-estradiol (E2) promotes metabolic homeostasis in premenopausal women. In a mouse model of post-menopausal metabolic syndrome, we reported that estrogens increased energy expenditure, thus preventing estrogen def
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c4fb8b85ae338bc0f24b4273070de4
http://www.sciencedirect.com/science/article/pii/S221287781831202X
http://www.sciencedirect.com/science/article/pii/S221287781831202X