Zobrazeno 1 - 10
of 87 104
pro vyhledávání: '"Ellis P"'
Autor:
Andy Tran, Andy Wang, Jamie Mickaill, Dario Strbenac, Mark Larance, Stephen T. Vernon, Stuart M. Grieve, Gemma A. Figtree, Ellis Patrick, Jean Yee Hwa Yang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract In the enduring challenge against disease, advancements in medical technology have empowered clinicians with novel diagnostic platforms. Whilst in some cases, a single test may provide a confident diagnosis, often additional tests are requir
Externí odkaz:
https://doaj.org/article/e78c45ecc8384f248fa19ebfd1922637
Publikováno v:
International Journal of COPD, Vol Volume 19, Pp 149-159 (2024)
Paul Ellis,1,2 Emily Bailey,2 Radmila Choate,3 Kristen E Holm,4,5 Robert A Sandhaus,5,6 Alice M Turner,1,2 Michael Newnham1,2 1Institute of Applied Health Research, University of Birmingham, Birmingham, UK; 2University Hospitals Birmingham NHS Founda
Externí odkaz:
https://doaj.org/article/4476f30b272c41f0a006e4a64691661e
Autor:
Xiaohang Fu, Yingxin Lin, David M. Lin, Daniel Mechtersheimer, Chuhan Wang, Farhan Ameen, Shila Ghazanfar, Ellis Patrick, Jinman Kim, Jean Y. H. Yang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Recent advances in subcellular imaging transcriptomics platforms have enabled high-resolution spatial mapping of gene expression, while also introducing significant analytical challenges in accurately identifying cells and assigning transcri
Externí odkaz:
https://doaj.org/article/9e3ea5cddd3a493ea0d1a894b632c3ba
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The recent emergence of multi-sample multi-condition single-cell multi-cohort studies allows researchers to investigate different cell states. The effective integration of multiple large-cohort studies promises biological insights into cells
Externí odkaz:
https://doaj.org/article/5df7d3c0817f428abd833cc97482af95
Autor:
Kerry McGregor, John L. McKenna, Ellis P. Barrera, Coleen R. Williams, Sydney M. Hartman-Munick, Carly E. Guss
Publikováno v:
Journal of Eating Disorders, Vol 11, Iss 1, Pp 1-12 (2023)
Abstract Background It has been well established that individuals who identify as lesbian, gay, bisexual, transgender, and queer are at increased risk for mental health pathology, including eating disorders/disordered eating behaviors (ED/DEB). Howev
Externí odkaz:
https://doaj.org/article/b6664f2e24e6405ab04952c288d27cb8
Autor:
Marni Torkel, Pengyi Yang, Shila Ghazanfar, Nick Robertson, Yingxin Lin, Andy Tran, Hani Kim, Yue Cao, Ellis Patrick, Jean Yang
Publikováno v:
F1000Research, Vol 12 (2023)
Background Globally, scientists now have the ability to generate a vast amount of high throughput biomedical data that carry critical information for important clinical and public health applications. This data revolution in biology is now creating a
Externí odkaz:
https://doaj.org/article/b1cb292ee8f8437da35157efe799d686
Autor:
Yizhe Mao, Tuba N. Gide, Nurudeen A. Adegoke, Camelia Quek, Nigel Maher, Alison Potter, Ellis Patrick, Robyn P. M. Saw, John F. Thompson, Andrew J. Spillane, Kerwin F. Shannon, Matteo S. Carlino, Serigne N. Lo, Alexander M. Menzies, Inês Pires da Silva, Georgina V. Long, Richard A. Scolyer, James S. Wilmott
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Gene expression profiling is increasingly being utilised as a diagnostic, prognostic and predictive tool for managing cancer patients. Single-sample scoring approach has been developed to alleviate instability of signature scores
Externí odkaz:
https://doaj.org/article/ef7110af153c44aabefb4fbcf176e3ad
Autor:
Ines Pires da Silva, Richard A Scolyer, Georgina Long, Matteo S Carlino, Ismael A Vergara, James S Wilmott, Serigne N Lo, Tuba N Gide, Alexander Maxwell Menzies, Nurudeen A Adegoke, Yizhe Mao, Camelia Quek, Ellis Patrick
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Tumor microenvironment (TME) characteristics are potential biomarkers of response to immune checkpoint inhibitors in metastatic melanoma. This study developed a method to perform unsupervised classification of TME of metastatic melanoma.Me
Externí odkaz:
https://doaj.org/article/6850a655f74044878275417fb41be554
Autor:
Adam S. Chan, Songhua Wu, Stephen T. Vernon, Owen Tang, Gemma A. Figtree, Tongliang Liu, Jean Y.H. Yang, Ellis Patrick
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106633- (2023)
Summary: Cardiovascular disease remains a leading cause of mortality with an estimated half a billion people affected in 2019. However, detecting signals between specific pathophysiology and coronary plaque phenotypes using complex multi-omic discove
Externí odkaz:
https://doaj.org/article/1e3bd3bd2ce74709add12efe4fe44c71
Autor:
Kevin Y. X. Wang, Gulietta M. Pupo, Varsha Tembe, Ellis Patrick, Dario Strbenac, Sarah-Jane Schramm, John F. Thompson, Richard A. Scolyer, Samuel Muller, Garth Tarr, Graham J. Mann, Jean Y. H. Yang
Publikováno v:
npj Digital Medicine, Vol 5, Iss 1, Pp 1-10 (2022)
Abstract In this modern era of precision medicine, molecular signatures identified from advanced omics technologies hold great promise to better guide clinical decisions. However, current approaches are often location-specific due to the inherent dif
Externí odkaz:
https://doaj.org/article/3d71487b9a0f4a00adbcd5e15337acb8