Lesiones papilares de mama: estudio clínico-patológico y sobre pronóstico en 144 casos de Medellín, Colombia Barra lateral del artículo Enviado: oct 6, 2021 Publicado: oct 13, 2021 DOI: https://doi.org/10.18566/medupb.v40n2.a02 Descargas Los datos de descargas todavía no están disponibles. Cómo citar Bonilla Sepúlveda, Óscar A. . (2021). Lesiones papilares de mama: estudio clínico-patológico y sobre pronóstico en 144 casos de Medellín, Colombia. Medicina UPB, 40(2), 2-12. https://doi.org/10.18566/medupb.v40n2.a02 0 Creative Commons License Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0. Contenido principal del artículo Óscar Alejandro Bonilla Sepúlveda UniRemington Biografía Grupo de investigaciones Biomédicas, UniRemington, Medellín, Colombia Resumen Objetivo: describir los datos sociodemográficos, las manifestaciones clínicas, los paraclínicos, el tratamiento y la recurrencia, en un grupo de pacientes con lesiones papilares. Metodología: estudio analítico de cohorte retrospectiva con fuentes secundarias de información, historias clínicas. Se incluyeron pacientes evaluados entre el 1º enero de 2016 y el 31 de diciembre de 2019. Se recopilaron datos demográficos, clínicos y paraclínicos, que fueron analizados con estadística descriptiva. Resultados: la prevalencia en la muestra fue de 4.7%; todos los casos fueron en mujeres, la media de edad fue 55,5 años; el motivo de consulta más frecuente fue alteración en la imagen de mama (n=79, 54.9%), el tamaño medio de la lesión fue 1,9 cm (rango 0,1-20). Se encontró discordancia entre el diagnóstico por biopsia cortante y el espécimen de patología en 70 (48.6%) casos, en estos se encontró infraestimación de lesiones con mayor riesgo en el 36,1% (n=52). Según la clasificación histológica, el tipo más frecuente de lesión fue el papiloma intraductal 34.7% (n=50), seguido por el carcinoma papilar en 11,8% (n=17). El tipo de cirugía más efectuado fue la cuadrantectomía, con un 68.7% (n=99). La media de seguimiento fue de 28.5 meses y se encontró recaída en siete casos (4.9%). Conclusión: las lesiones papilares comprenden un grupo heterogéneo, que incluye desde las benignas hasta aquellas con potencial maligno. Afectan a las mujeres en la quinta década de la vida, se presentan como una masa, pequeña, unilateral, sin predominio de lateralidad, de crecimiento lento. El tratamiento óptimo para las lesiones de riesgo y con atipias es la cirugía con márgenes negativos, el riesgo de recurrencia es clínicamente relevante. Palabras clave: breast neoplasms, intraductal papiloma, papillary cystadenoma, papillary carcinoma neoplasias de la mama, papiloma intraductal, cistoadenoma papilar, carcinoma papilar neoplasias mamárias, papiloma intraductal, cistadenoma papilar, carcinoma papilar Detalles del artículo Referencias Sakr R, Rouzier R, Salem C, Antoine M, Chopier J, Daraï E, et al. 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Autor: Óscar Alejandro Bonilla Sepúlveda

Publikováno v: Medicina UPB. 40:2-12

Objetivo: describir los datos sociodemográficos, las manifestaciones clínicas, los paraclínicos, el tratamiento y la recurrencia, en un grupo de pacientes con lesiones papilares. Metodología: estudio analítico de cohorte retrospectiva con fuente

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https://doi.org/10.18566/medupb.v40n2.a02

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Autor: Lo Y; From the Departments of Epidemiology and Population Health (Lo) and Pathology (Fineberg, Lanjewar, Laurini, Ustun, Harmon, Edema, Sapna), Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York., Lester SC; the Department of Pathology, Brigham and Women's Hospital and the Dana-Farber/Harvard Cancer Center, Boston, Massachusetts (Lester, Aldrees, Ngo, Schnitt)., Ellis IO; the Department of Histopathology, University of Nottingham/Nottingham City Hospital, Nottingham, United Kingdom (Ellis)., Lanjewar S; From the Departments of Epidemiology and Population Health (Lo) and Pathology (Fineberg, Lanjewar, Laurini, Ustun, Harmon, Edema, Sapna), Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York., Laurini J; From the Departments of Epidemiology and Population Health (Lo) and Pathology (Fineberg, Lanjewar, Laurini, Ustun, Harmon, Edema, Sapna), Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York., Patel A; the Department of Pathology, NewYork-Presbyterian/Weill Cornell Medicine, New York, New York (Patel)., Bhattarai A; the Department of Pathology, Methodist University Hospital, Memphis, Tennessee (Bhattarai, Bradley)., Ustun B; From the Departments of Epidemiology and Population Health (Lo) and Pathology (Fineberg, Lanjewar, Laurini, Ustun, Harmon, Edema, Sapna), Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York., Harmon B; From the Departments of Epidemiology and Population Health (Lo) and Pathology (Fineberg, Lanjewar, Laurini, Ustun, Harmon, Edema, Sapna), Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York., Kleer CG; the Department of Pathology, University of Michigan, Ann Arbor (Kleer, Abbott)., Ross D; the Department of Pathology Memorial Sloan Kettering Cancer Center, New York, New York (Ross, D'Alfonso)., Amin A; the Department of Pathology, Warren Alpert Medical School of Brown University, Providence, Rhode Island (Amin, Wang, Singh)., Wang Y; the Department of Pathology, Warren Alpert Medical School of Brown University, Providence, Rhode Island (Amin, Wang, Singh)., Bradley R; the Department of Pathology, Methodist University Hospital, Memphis, Tennessee (Bhattarai, Bradley)., Turashvili G; the Department of Pathology, Emory University Hospital, Atlanta, Georgia (Turashvili, Badve)., Zeng J; the Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York (Zeng, Collins)., Baum J; the Department of Pathology, NYU Langone Hospital, Mineola, New York (Baum, Ginter, Flieder)., Singh K; the Department of Pathology, Warren Alpert Medical School of Brown University, Providence, Rhode Island (Amin, Wang, Singh)., Hakima L; the Department of Pathology, University of North Carolina Hospitals, Chapel Hill (Hakima)., Harigopal M; the Department of Pathology, Yale University School of Medicine, New Haven, Connecticut (Harigopal)., Komforti M; the Department of Pathology, Mayo Clinic, Jacksonville, Florida (Komforti, Nassar)., Shin SJ; the Department of Pathology, Albany Medical College, Albany, New York (Shin)., Abbott SE; the Department of Pathology, University of Michigan, Ann Arbor (Kleer, Abbott)., Jaffer S; the Department of Pathology, Lenox Hill Hospital/Northwell Health, New York, New York (Jaffer)., Badve SS; the Department of Pathology, Emory University Hospital, Atlanta, Georgia (Turashvili, Badve)., Khoury T; the Department of Pathology, Roswell Park Cancer Institute, Buffalo, New York (Khoury)., D'Alfonso TM; the Department of Pathology Memorial Sloan Kettering Cancer Center, New York, New York (Ross, D'Alfonso)., Ginter PS; the Department of Pathology, NYU Langone Hospital, Mineola, New York (Baum, Ginter, Flieder)., Collins V; the Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, New York (Zeng, Collins)., Towne W; the Department of Pathology, Columbia University/New York Presbyterian Hospital, New York, New York (Towne)., Gan Y; the Department of Pathology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire (Gan)., Nassar A; the Department of Pathology, Mayo Clinic, Jacksonville, Florida (Komforti, Nassar)., Sahin AA; the Department of Pathology, MD Anderson Cancer Center, Houston, Texas (Sahin)., Flieder A; the Department of Pathology, NYU Langone Hospital, Mineola, New York (Baum, Ginter, Flieder)., Aldrees R; the Department of Pathology, Brigham and Women's Hospital and the Dana-Farber/Harvard Cancer Center, Boston, Massachusetts (Lester, Aldrees, Ngo, Schnitt)., Ngo MH; the Department of Pathology, Brigham and Women's Hospital and the Dana-Farber/Harvard Cancer Center, Boston, Massachusetts (Lester, Aldrees, Ngo, Schnitt)., Edema U; From the Departments of Epidemiology and Population Health (Lo) and Pathology (Fineberg, Lanjewar, Laurini, Ustun, Harmon, Edema, Sapna), Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York., Sapna F; From the Departments of Epidemiology and Population Health (Lo) and Pathology (Fineberg, Lanjewar, Laurini, Ustun, Harmon, Edema, Sapna), Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York., Schnitt SJ; the Department of Pathology, Brigham and Women's Hospital and the Dana-Farber/Harvard Cancer Center, Boston, Massachusetts (Lester, Aldrees, Ngo, Schnitt)., Fineberg SA; From the Departments of Epidemiology and Population Health (Lo) and Pathology (Fineberg, Lanjewar, Laurini, Ustun, Harmon, Edema, Sapna), Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York.

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Autor: Evans H; Histopathology Department, University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry, CV2 2DX, UK. harriet.evans4@nhs.net.; Warwick Medical School, University of Warwick, Coventry, UK. harriet.evans4@nhs.net., Kimani PK; Clinical Trials Unit, University of Warwick, Coventry, UK., Hiller L; Clinical Trials Unit, University of Warwick, Coventry, UK., Tsang YW; Histopathology Department, University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry, CV2 2DX, UK., Sah S; Histopathology Department, University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry, CV2 2DX, UK., Gopalakrishnan K; Histopathology Department, University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry, CV2 2DX, UK., Boyd C; Belfast Health and Social Care Trust, Belfast, UK., Loughrey MB; Belfast Health and Social Care Trust, Belfast, UK.; Queen's University, Belfast, UK., Kelly PJ; Belfast Health and Social Care Trust, Belfast, UK., Boyle DP; Belfast Health and Social Care Trust, Belfast, UK., Clark D; Nottingham University Hospital NHS Trust, Nottingham, UK., Ellis IO; Nottingham University Hospital NHS Trust, Nottingham, UK.; University of Nottingham, Nottingham, UK., Ilyas M; University of Nottingham, Nottingham, UK., Rakha E; Nottingham University Hospital NHS Trust, Nottingham, UK.; University of Nottingham, Nottingham, UK.; Hamad Medical Corporation, Doha, Qatar., Bickers A; Northern Lincolnshire and Goole NHS Foundation Trust, Scunthorpe, UK., Roberts ISD; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Soares MF; Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Neil DAH; Birmingham NHS Foundation Trust, Birmingham, UK.; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Dunn JA; Clinical Trials Unit, University of Warwick, Coventry, UK., Azam A; Histopathology Department, University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry, CV2 2DX, UK., Snead D; Histopathology Department, University Hospitals Coventry and Warwickshire NHS Trust, Clifford Bridge Road, Coventry, CV2 2DX, UK.; Computer Science Department, University of Warwick, Coventry, UK.

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