Validation of a host blood transcriptomic biomarker for pulmonary tuberculosis in people living with HIV: a prospective diagnostic and prognostic accuracy study

Autor: Simon C Mendelsohn, MBChB, Andrew Fiore-Gartland, PhD, Adam Penn-Nicholson, PhD, Humphrey Mulenga, MPH, Stanley Kimbung Mbandi, PhD, Bhavesh Borate, MS, Katie Hadley, PhD, Chris Hikuam, PhD, Munyaradzi Musvosvi, PhD, Nicole Bilek, PhD, Mzwandile Erasmus, BSc, Lungisa Jaxa, BTech, Rodney Raphela, BSc, Onke Nombida, GT, Masooda Kaskar, MBChB, Tom Sumner, PhD, Richard G White, PhD, Craig Innes, MBChB, William Brumskine, MBChB, Andriëtte Hiemstra, MBChB, Stephanus T Malherbe, MBChB, Razia Hassan-Moosa, MPH, Michèle Tameris, MBChB, Gerhard Walzl, MBChB, Kogieleum Naidoo, PhD, Gavin Churchyard, PhD, Thomas J Scriba, DPhil, Mark Hatherill, ProfMD, Charmaine Abrahams, Hadn Africa, Petri Ahlers, Denis Arendsen, Tebogo Badimo, Kagiso Baepanye, Kesenogile Edna Baepanye, Bianca Bande, Nomfuneko Cynthia Batyi, Roslyn Beukes, Laudicia Tshenolo Bontsi, Obakeng Peter Booi, Mari Cathrin Botha, Samentra Braaf, Sivuyile Buhlungu, Alida Carstens, Kgomotso Violet Chauke, Thilagavathy Chinappa, Eva Chung, Michelle Chung, Ken Clarke, Yolundi Cloete, Lorraine Coetzee, Marelize Collignon, Alessandro Companie, Cara-mia Corris, Mooketsi Theophillius Cwaile, Thobelani Cwele, Ilse Davids, Isabella Johanna Davies, Emilia De Klerk, Marwou de Kock, Audrey Lebohang Dhlamini, Bongani Diamond, Maria Didloff, Celaphiwe Dlamini, Palesa Dolo, Candice Eyre, Tebogo Feni, Juanita Ferreira, Christal Ferus, Michelle Fisher, Marika Flinn, Bernadine Fransman, Welseh Phindile Galane, Hennie Geldenhuys, Diann Gempies, Thelma Goliath, Dhineshree Govender, Yolande Gregg, Goodness Gumede, Zanele Gwamada, Senzo Halti, Rieyaat Hassiem, Roxane Herling, Yulandi Herselman, Ellis Hughes, Henry Issel, Blanchard Mbay Iyemosolo, Zandile Jali, Bonita Janse Van Rensburg, Ruwiyda Jansen, James Michael Jeleni, Olebogeng Jonkane, Fabio Julies, Fazlin Kafaar, Christian Mabika Kasongo, Sophie Keffers, Boitumelo Sophy Kekana, Sebaetseng Jeanette Kekana, Xoliswa Kelepu, Lungile Khanyile, Gomotsegang Virginia Khobedi, Gloria Khomba, Lucky Sipho Khoza, Marietjie King, Gloria Keitumetse Kolobe, Sandra Kruger, Jaftha Kruger, Ndlela Israel Kunene, Sunelza Lakay, Aneesa Lakhi, Nondumiso Langa, Hildah Ledwaba, Lerato Julia Lekagane, Sheiley Christina Lekotloane, Thelma Leopeng, Ilze Jeanette Louw, Angelique Kany Kany Luabeya, Sarah Teboso Lusale, Perfect Tiisetso Maatjie, Immaculate Mabasa, Tshegofatso Dorah Mabe, Kamogelo Fortunate Mabena, Nkosinathi Charles Mabuza, Simbarashe Mabwe, Johanna Thapelo Madikwe, Octavia Mahkosazana Madikwe, Rapontwana Letlhogonolo Maebana, Malobisa Sylvester Magwasha, Molly Majola, Mantai Makhetha, Lebohang Makhethe, Vernon Malay, Vutlhari-I-Vunhenha Fairlord Manzini, Jabu Maphanga, Nonhle Maphanga, Juanita Market, Isholedi Samuel Maroele, Omphile Petunia Masibi, July Rocky Mathabanzini, Tendamudzimu Ivan Mathode, Ellen Ditaba Matsane, Lungile Mbata, Faheema Meyer, Nyasha Karen Mhandire, Thembisiwe Miga, Nosisa Charity Thandeka Mkhize, Caroline Mkhokho, Neo Hilda Mkwalase, Nondzakazi Mnqonywa, Karabo Moche, Brenda Matshidiso Modisaotsile, Patricia Pakiso Mokgetsengoane, Selemeng Matseliso Carol Mokone, Kegomoditswe Magdeline Molatlhegi, Thuso Andrew Molefe, Joseph Panie Moloko, Kabelo Molosi, Motlatsi Evelyn Molotsi, Tebogo Edwin Montwedi, Boikanyo Dinah Monyemangene, Hellen Mokopi Mooketsi, Miriam Moses, Boitumelo Mosito, Tshplpfelo Mapula Mosito, Ireen Lesebang Mosweu, Primrose Mothaga, Banyana Olga Motlagomang, Angelique Mouton, Onesisa Mpofu, Funeka Nomvula Mthembu, Mpho Mtlali, Nhlamulo Ndlovu, Nompumelelo Ngcobo, Julia Noble, Bantubonke Bertrum Ntamo, Gloria Ntanjana, Tedrius Ntshauba, Fajwa Opperman, Nesri Padayatchi, Thandiwe Papalagae, Christel Petersen, Themba Phakathi, Mapule Ozma Phatshwane, Patiswa Plaatjie, Abe Pretorius, Victor Kgothatso Rameetse, Dirhona Ramjit, Frances Ratangee, Maigan Ratangee, Pearl Nomsa Sanyaka, Alicia Sato, Elisma Schoeman, Constance Schreuder, Letlhogonolo Seabela, Kelebogile Magdeline Segaetsho, Ni Ni Sein, Raesibe Agnes Pearl Selepe, Melissa Neo Senne, Alison September, Cashwin September, Moeti Serake, Justin Shenje, Thandiwe Shezi, Sifiso Cornelius Shezi, Phindile Sing, Chandrapharbha Singh, Zona Sithetho, Dorothy Solomons, Kim Stanley, Marcia Steyn, Bongiwe Stofile, Sonia Stryers, Liticia Swanepoel, Anne Swarts, Mando Mmakhora Thaba, Lethabo Collen Theko, Philile Thembela, Mugwena Thompo, Asma Toefy, Khayalethu Toto, Dimakatso Sylvia Tsagae, Ayanda Tsamane, Vincent Tshikovhi, Lebogang Isaac Tswaile, Petrus Tyambetyu, Susanne Tönsing, Habibullah Valley, Linda van der Merwe, Elma van Rooyen, Ashley Veldsman, Helen Veldtsman, Kelvin Vollenhoven, Londiwe Zaca, Elaine Zimri, Mbali Zulu

Publikováno v: The Lancet Global Health, Vol 9, Iss 6, Pp e841-e853 (2021)

Summary: Background: A rapid, blood-based triage test that allows targeted investigation for tuberculosis at the point of care could shorten the time to tuberculosis treatment and reduce mortality. We aimed to test the performance of a host blood tra

Externí odkaz: https://doaj.org/article/abc3602cf70749b5a1d464dd9cecb502

The Rockerverse: Packages and Applications for Containerization with R

Autor: Dirk Eddelbuettel, Charlotte Van Petegem, Noam Ross, Colin Fay, Jacqueline Nolis, Nan Xiao, Hong Ooi, Mark Edmondson, Jason Williams, Ellis Hughes, Lori Shepherd, Péter Sólymos, Tyson L. Swetnam, Lars Kjeldgaard, Sean Lopp, Karthik Ram, Ben Marwick, Craig Willis, Heather Nolis, Gergely Daróczi, Nitesh Turaga, Robrecht Cannoodt, Dav Clark, Dom Bennett, Daniel Nüst

Publikováno v: R JOURNAL

The Rocker Project provides widely used Docker images for R across different application scenarios. This article surveys downstream projects that build upon the Rocker Project images and presents the current state of R packages for managing Docker im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a76c99e524c371bdc0d3a9026743da
http://arxiv.org/abs/2001.10641

Gravitational demand on the neck musculature during tablet computer use

Autor: David C. Lin, Derek Nevins, Anita N. Vasavada, Ellis Hughes, Steven M. Monda

Publikováno v: Ergonomics. 58:990-1004

Tablet computer use requires substantial head and neck flexion, which is a risk factor for neck pain. The goal of this study was to evaluate the biomechanics of the head-neck system during seated tablet computer use under a variety of conditions. A p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d25fc1ca5cb6b9cfc664ff9f4d8aa7
https://doi.org/10.1080/00140139.2015.1005166

Vascular surgery case report: Trellis-8 pharmaco-mechanical thrombectomy system for the treatment of iliofemoral deep venous thrombosis

Autor: Sriram Narayanan, James Rigby, Ellis Hughes, Paul Ellis, Mark Cowling

Publikováno v: International Journal of Surgery. 9:538

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfe352b3ac37158d64caedee43518e1
https://doi.org/10.1016/j.ijsu.2011.07.215