Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ellis G. Jaffray"'
Autor:
Paul Murphy, Yingqi Xu, Sarah L. Rouse, Ellis G. Jaffray, Anna Plechanovová, Steve J. Matthews, J. Carlos Penedo, Ronald T. Hay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
RNF4 is a prototypical single-subunit E3 enzyme that can bind both substrate and ubiquitin-loaded E2. Here, the authors show that the RNF4 N-terminal region, although lacking a defined secondary structure, maintains a compact global conformation to f
Externí odkaz:
https://doaj.org/article/c9de74e062a44078a1b0ae8e8b67bf15
Autor:
Ellis G. Jaffray, Michael H. Tatham, Barbara Mojsa, Magda Liczmanska, Alejandro Rojas-Fernandez, Yili Yin, Graeme Ball, Ronald T. Hay
Publikováno v:
Journal of Cell Biology. 222
Acute Promyelocytic Leukemia is caused by expression of the oncogenic Promyelocytic Leukemia (PML)–Retinoic Acid Receptor Alpha (RARA) fusion protein. Therapy with arsenic trioxide results in degradation of PML-RARA and PML and cures the disease. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b838c2b7933d353cf342d4404059e47
https://doi.org/10.1083/jcb.202201027
https://doi.org/10.1083/jcb.202201027
Autor:
Ellis G. Jaffray, Michael H. Tatham, Alejandro Rojas-Fernandez, Adel Ibrahim, Graeme Ball, Ronald T. Hay
Arsenic is an effective treatment for Acute Promyelocytic Leukaemia as it induces degradation of the Promyelocytic Leukaemia (PML) – retinoic acid receptor alpha (RARA) oncogenic fusion protein. Some patients relapse with arsenic resistant disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb92432dba7534e299c078ea5da0027e
https://doi.org/10.1101/2023.01.15.524136
https://doi.org/10.1101/2023.01.15.524136
Publikováno v:
Journal of Cell Science
Oocyte meiotic spindles in most species lack centrosomes and the mechanisms that underlie faithful chromosome segregation in acentrosomal meiotic spindles are not well understood. In C. elegans oocytes, spindle microtubules exert a poleward force on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f60ac5cef48293c8fe815f76ac7d9ab5
https://pubmed.ncbi.nlm.nih.gov/31243051
https://pubmed.ncbi.nlm.nih.gov/31243051
Autor:
Federico, Pelisch, Triin, Tammsalu, Bin, Wang, Ellis G, Jaffray, Anton, Gartner, Ronald T, Hay
Publikováno v:
Molecular Cell
Summary During Caenorhabditis elegans oocyte meiosis, a multi-protein ring complex (RC) localized between homologous chromosomes, promotes chromosome congression through the action of the chromokinesin KLP-19. While some RC components are known, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e64362df2bc3b78a9d86b769e1c8131
https://pubmed.ncbi.nlm.nih.gov/27939944
https://pubmed.ncbi.nlm.nih.gov/27939944
Autor:
Edward F, Makiyi, Raquel F M, Frade, Tomas, Lebl, Ellis G, Jaffray, Susan E, Cobb, Alan L, Harvey, Alexandra M Z, Slawin, Ronald T, Hay, Nicholas J, Westwood
Publikováno v:
European Journal of Organic Chemistry
The isolation, identification and total synthesis of two plant-derived inhibitors of the NF-κB signaling pathway from the iso-seco-tanapartholide family of natural products is described. A key step in the efficient reaction sequence is a late-stage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::90b0789e1fcfdb131ad4c02c7910c5cc
https://pubmed.ncbi.nlm.nih.gov/23606807
https://pubmed.ncbi.nlm.nih.gov/23606807
Autor:
Ivan Matic, Ellis G. Jaffray, Senga K. Oxenham, Michael J. Groves, Christopher L. R. Barratt, Sudhir Tauro, Nicola R. Stanley-Wall, Ronald T. Hay
Publikováno v:
Journal of Proteome Research; Oct2011, Vol. 10 Issue 10, p4869-4875, 7p
Publikováno v:
Biochemical Journal; Jun2009, Vol. 421 Issue 2, p223-230, 8p