Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Ellis E. Golub"'
Publikováno v:
Journal of periodontology. 67
Actinobacillus actinomycetemcomitans has been implicated as a causative organism in early-onset periodontitis. The mechanisms by which A. actinomycetemcomitans is pathogenic are not known, but the organism produces several potential virulence factors
Autor:
William R. Abrams, Daniel Malamud, Cheryl A. Barber, Ellis E. Golub, M. Rehtanz, Drew Weissman
Publikováno v:
Advances in Dental Research. 23:34-37
In this review, the authors survey the large number of antibacterial and antiviral proteins present in human saliva. Of interest, most of these antibacterial proteins display antiviral activity, typically against specific viral pathogens. The review
Publikováno v:
Journal of Biological Chemistry. 286:746-756
IRF-7 is the master regulator of type I interferon-dependent immune responses controlling both innate and adaptive immunity. Given the significance of IRF-7 in the induction of immune responses, many viruses have developed strategies to inhibit its a
Autor:
Ellis E. Golub
Publikováno v:
Seminars in Immunopathology. 33:409-417
In normal healthy individuals, mineral formation is restricted to specialized tissues which form the skeleton and the dentition. Within these tissues, mineral formation is tightly controlled both in growth and development and in normal adult life. Th
Publikováno v:
Oral Diseases. 17:427-432
Oral Diseases (2011) 17, 427–432 Objectives: Bisphosphonates commonly used to treat osteoporosis, Paget’s disease, multiple myeloma, hypercalcemia of malignancy and osteolytic lesions of cancer metastasis have been associated with bisphosphonate-
Publikováno v:
Journal of Bone and Mineral Research. 15:261-270
Zinc (Zn2+) has long been known to play important roles in mineralization and ossification of skeletal tissues, but the mechanisms of Zn2+ action are not well understood. In this study we investigated the effects of Zn2+ on mineralization in a cell c
Publikováno v:
Journal of Bone and Mineral Research. 10:568-573
Alkaline phosphatase (AP) is required for the proper mineralization of cartilage and bone. The enzyme is localized to the outer surface of cells through a phosphatidylinositol-glycolipid anchor, which is covalently attached to the carboxyl terminus o
Autor:
Peter Frasca, Ellis E. Golub, John C. Haselgrove, Britton Chance, Irving M. Shapiro, Saburo Kakuta
Publikováno v:
Journal of Bone and Mineral Research. 1:433-440
The objective of this investigation was to examine the redox status of chondrocytes in normal and rachitic growth cartilages and to relate energy metabolism to cell maturation and the initiation of mineralization. The redox status was evaluated by ch
Autor:
Ellis E. Golub
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1790:1592-1598
Background Matrix vesicles have been implicated in the mineralization of calcified cartilage, bone and dentin for more than 40 years. During this period, their exact role, if any in the nucleation of hydroxyapatite mineral, and its subsequent associa
Publikováno v:
Analytical Biochemistry. 380:1-4
We have developed a nanogram-level quantitative protein assay based on the binding of colloidal gold to proteins adhered to nitrocellulose paper. The protein-gold complex produces a purple color proportional to the amount of protein present, and the