Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Elliott W. Chideckel"'
Autor:
Elliott W. Chideckel
Publikováno v:
JAMA: The Journal of the American Medical Association. 264:2994
To the Editor.— Though a number of drugs have been used for diabetic sweating and diabetic diarrhea, often the drugs are either insufficient or associated with disabling side effects.1,2Oxybutynin is an antimuscarinic receptorblocking agent that al
Publikováno v:
British Journal of Pharmacology. 92:609-614
1. The Na+,K+-pump has been implicated in animal models of airway hyperreactivity. We examined the effects of inhibiting the Na+,K+-pump and Na+,Ca2+-exchange on isometric tone of isolated trachealis from humans and other species. 2. In preparations
Publikováno v:
European Journal of Pharmacology. 116:187-190
Spermidine, spermine, and putreanine, a metabolite of spermidine, caused transient relaxation of the isolated guinea-pig trachealis. The spermidine effect was not blocked by ouabain, propranolol or indomethacin. Spermidine treatment was shown to dese
Autor:
Charles J. Goodner, Elliott W. Chideckel, Donna J. Koerker, Barbara C. Walike, Lynne W. Kalnasy
Publikováno v:
Journal of Medical Primatology. 6:151-162
Obesity was studied in a colony of 873 Macaca nemestrina to establish tools for epidemiologic studies, to examine a genetic form of obesity, to document age/sex relationships to obesity, and to compare metabolic profiles of obese and normal monkeys.
Publikováno v:
European Journal of Pharmacology. 166:367-372
It is known that after exposure to (3 mM) tetraethylammonium (TEA), guinea-pig isolated trachealis generates tonic spasm followed by phasic tension changes. We found that 8-Br-cAMP or 8-Br-cGMP (10(-6)-5 x 10(-4) M) suppressed tonic spasm secondary t
Non-β-cell tumor hypoglycemia associated with increased nonsuppressible insulin-like protein (NSILP)
Autor:
Thomas T. Aoki, Herbert Plovnick, Elliott W. Chideckel, Philip L. Poffenbarger, Neil B. Ruderman
Publikováno v:
The American Journal of Medicine. 66:154-159
An elderly woman with a massive intra-abdominal fibrosarcoma was noted to have intermittent hypoglycemia . When present, the hypoglycemia was associated with diminished levels of free fatty acids and ketone bodies and an increase in plasma NSILP . Le
Autor:
Arthur C. Brown, Jerry P. Palmer, Lynne W. Kalnasy, Barbara C. Walike, Charles J. Goodner, Donna J. Koerker, Elliott W. Chideckel, John W. Ensinck
Publikováno v:
Science. 195:177-179
In overnight fasted rhesus monkeys, synchronous, regular oscillations occurred in the plasma concentrations of glucose, insulin, and glucagon. The oscillations displayed a period averaging 9 minutes. The amplitudes for insulin and glucagon were ten a
Autor:
Jerry P. Palmer, Willy Ruch, John W. Ensinck, Charles J. Goodner, Charles C. Gale, Donna J. Koerker, Elliott W. Chideckel
Publikováno v:
Science. 184:482-484
Somatostatin, a hypothalamic peptide that inhibits the secretion of pituitary growth hormone, inhibits basal insulin secretion in fasted cats and rats. In fasted baboons both basal and arginine-stimulated secretion of insulin and glucagon are inhibit
Publikováno v:
Cardiovascular research. 20(12)
Polyamines, found in all nucleated cells, have been shown to relax uterine, gastrointestinal, and respiratory tract smooth muscle. When parenterally administered to the rat or dog they cause hypotension. To determine the range of the relaxing effect
Publikováno v:
British journal of pharmacology. 89(1)
We have previously observed a paradoxical relaxant effect of K+ on guinea-pig isolated trachealis after exposure to polyamines. The purpose of the present study was to evaluate whether the relaxation involved a reduction in the entry of extracellular