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pro vyhledávání: '"Elliott P Brooks"'
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008507 (2019)
Deleterious genetic mutations allow developmental biologists to understand how genes control development. However, not all loss of function genetic mutants develop phenotypic changes. Many deleterious mutations only produce a phenotype in a subset of
Externí odkaz:
https://doaj.org/article/dbbd60bca2434366a651ab10d9081087
Autor:
Elliott P Brooks, Lori Sussel
Publikováno v:
Journal of Endocrinology.
Historic and emerging studies provide evidence for the deterioration of pancreatic α cell function and identity in diabetes mellitus. Increased access to human tissue and the availability of more sophisticated molecular technologies have revealed ke
Autor:
Juliana Sucharov, Anthony T Pulvino, Austin E. Gillen, Jennyfer M Mitchell, James T. Nichols, Elliott P. Brooks
Publikováno v:
Development
During craniofacial development, different populations of cartilage- and bone-forming cells develop in precise locations in the head. Most of these cells are derived from pluripotent cranial neural crest cells and differentiate with distinct developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3aa7f9dfd2cf7592bfe989698366a5
https://europepmc.org/articles/PMC8077506/
https://europepmc.org/articles/PMC8077506/
Selective breeding modifies mef2ca mutant incomplete penetrance by tuning the opposing Notch pathway
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 15, Iss 12, p e1008507 (2019)
PLoS Genetics, Vol 15, Iss 12, p e1008507 (2019)
Deleterious genetic mutations allow developmental biologists to understand how genes control development. However, not all loss of function genetic mutants develop phenotypic changes. Many deleterious mutations only produce a phenotype in a subset of
Autor:
James T. Nichols, Elliott P. Brooks
Zebrafish mutant phenotypes are often incompletely penetrant, only manifesting in some mutants. Interesting phenotypes that inconsistently appear can be difficult to study, and can lead to confounding results. The protocol described here is a straigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3d1239ca4fd619ca73979c2a145e16
https://europepmc.org/articles/PMC5614404/
https://europepmc.org/articles/PMC5614404/