Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elliott M McMillan"'
Autor:
Elliott M McMillan, Marie-France Paré, Brittany L Baechler, Drew A Graham, James W E Rush, Joe Quadrilatero
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119382 (2015)
Hypertension is a cardiovascular disease associated with deleterious effects in skeletal and cardiac muscle. Autophagy is a degradative process essential to muscle health. Acute exercise can alter autophagic signaling. Therefore, we aimed to characte
Externí odkaz:
https://doaj.org/article/b7ecce9d1bc74c949a9fb40f24efa9e8
Autor:
Andrew Hopf, Catherine Bellissimo, A. Russell Tupling, Ian C. Smith, Elliott M. McMillan, Mark A. Tarnopolsky, Khanh Tran, Val A. Fajardo, Brennan J. Wadsworth, Eric Bombardier, Robin N. Michel, Daniel Gamu, Joe Quadrilatero, Chris Vigna
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 8, Pp 999-1009 (2015)
Disease Models & Mechanisms
Disease Models & Mechanisms
Centronuclear myopathy (CNM) is a congenital myopathy that is histopathologically characterized by centrally located nuclei, central aggregation of oxidative activity, and type I fiber predominance and hypotrophy. Here, we obtained commercially avail
Autor:
Joe Quadrilatero, Elliott M. McMillan
Publikováno v:
Biochemical Journal. 462:267-277
Several degradative systems assist in formation of multinucleated terminally differentiated myotubes. However, the role of autophagy in this process has not been examined. GFP–LC3B (light chain 3 beta) puncta, LC3B-II protein and LysoTracker fluore
Autor:
Joe Quadrilatero, Elliott M. McMillan, William Gittings, A. Russell Tupling, Jian Huang, Ian C. Smith, Rene Vandenboom
Publikováno v:
The Journal of General Physiology
The increase in isometric twitch force observed in fast-twitch rodent muscles during or after activity, known universally as potentiation, is normally associated with myosin regulatory light chain (RLC) phosphorylation. Interestingly, fast muscles fr
Autor:
John G. Mielke, Dmytro Pavlov, Darin Bloemberg, Andrew S. Mitchell, Elliott M. McMillan, Troy L. Campbell, Joe Quadrilatero, Isabelle Messa
Apoptosis and autophagy are critical in normal skeletal muscle homeostasis; however, dysregulation can lead to muscle atrophy and dysfunction. Lipotoxicity and/or lipid accumulation may promote apoptosis, as well as directly or indirectly influence a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b42f175486c1fadf8d4c1bb9eaa8f8f
https://europepmc.org/articles/PMC4935269/
https://europepmc.org/articles/PMC4935269/
Autor:
Marie-France Paré, James W. E. Rush, Brittany L. Baechler, Elliott M. McMillan, Drew A. Graham, Joe Quadrilatero
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119382 (2015)
PLoS ONE
PLoS ONE
Hypertension is a cardiovascular disease associated with deleterious effects in skeletal and cardiac muscle. Autophagy is a degradative process essential to muscle health. Acute exercise can alter autophagic signaling. Therefore, we aimed to characte
Publikováno v:
Clinical biomechanics (Bristol, Avon). 30(9)
Background Previous research suggests that when the magnitude of peak compressive force applied during cyclic loading exceeds 30% of a functional spinal unit's estimated ultimate compressive tolerance, fatigue failure of the cartilaginous endplate or
Autor:
Eric A. Lee, Mahadeo A. Sukhai, Leonard Angka, Elliott M. McMillan, Thomas Hanlon, Paul A. Spagnuolo, Mark D. Minden, Joe Quadrilatero, Sarah G. Rota
Publikováno v:
Cancer letters. 348(1-2)
To identify novel anti-cancer agents, we created and screened a unique nutraceutical library for activity against acute myeloid leukemia (AML) cells. From this screen, we determined that glucopsychosine was selectively toxic toward AML cell lines and
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 113(7)
Cardiovascular diseases such as hypertension are associated with a generalized skeletal myopathy including a proapoptotic phenotype. Current evidence suggests that exercise may alter apoptosis-related signaling in skeletal muscle; however, the effect
Autor:
Elliott M McMillan, Ian Newhouse
Publikováno v:
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 36(6)
The use of exercise interventions to manage cancer-related fatigue (CRF) is a rapidly developing field of study. However, results are inconsistent and difficult to interpret across the literature, making it difficult to draw accurate conclusions rega