Zobrazeno 1 - 10
of 298
pro vyhledávání: '"Elliott Kieff"'
Autor:
Ina Ersing, Luis Nobre, Liang Wei Wang, Lior Soday, Yijie Ma, Joao A. Paulo, Yohei Narita, Camille W. Ashbaugh, Chang Jiang, Nicholas E. Grayson, Elliott Kieff, Steven P. Gygi, Michael P. Weekes, Benjamin E. Gewurz
Publikováno v:
Cell Reports, Vol 19, Iss 7, Pp 1479-1493 (2017)
Epstein-Barr virus (EBV) replication contributes to multiple human diseases, including infectious mononucleosis, nasopharyngeal carcinoma, B cell lymphomas, and oral hairy leukoplakia. We performed systematic quantitative analyses of temporal changes
Externí odkaz:
https://doaj.org/article/6d63a6d1609541e78227973b624273aa
Autor:
Frederik J. Verweij, Cecilia de Heus, Stefanie Kroeze, Houjian Cai, Elliott Kieff, Sander R. Piersma, Connie R. Jimenez, Jaap M. Middeldorp, Dirk Michiel Pegtel
Publikováno v:
Journal of Extracellular Vesicles, Vol 4, Iss 0, Pp 1-12 (2015)
The Epstein–Barr virus (EBV)-encoded oncoprotein latent membrane protein 1 (LMP1) constitutively activates nuclear factor κB (NFκB) from intracellular membranes to promote cell growth and survival. LMP1 associates with CD63 in intracellular membr
Externí odkaz:
https://doaj.org/article/b555fe7874e5439fa6b50d2f96aeff7d
Autor:
Bo Zhao, Luis A. Barrera, Ina Ersing, Bradford Willox, Stefanie C.S. Schmidt, Hannah Greenfeld, Hufeng Zhou, Sarah B. Mollo, Tommy T. Shi, Kaoru Takasaki, Sizun Jiang, Ellen Cahir-McFarland, Manolis Kellis, Martha L. Bulyk, Elliott Kieff, Benjamin E. Gewurz
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1595-1606 (2014)
The nuclear factor κB (NF-κΒ) subunits RelA, RelB, cRel, p50, and p52 are each critical for B cell development and function. To systematically characterize their responses to canonical and noncanonical NF-κB pathway activity, we performed chromat
Externí odkaz:
https://doaj.org/article/36415eb4404c419da9e5fcac60a1a559
Autor:
Xiaohui Zhou, Benjamin E. Gewurz, Jennifer M. Ritchie, Kaoru Takasaki, Hannah Greenfeld, Elliott Kieff, Brigid M. Davis, Matthew K. Waldor
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1690-1702 (2013)
Vibrio parahaemolyticus type III secretion system 2 (T3SS2) is essential for the organism’s virulence, but the effectors required for intestinal colonization and induction of diarrhea by this pathogen have not been identified. Here, we identify a t
Externí odkaz:
https://doaj.org/article/1cf8d026082240a49ef6d5bd8ae25c56
Autor:
Cheng-Der Liu, Ya-Lin Chen, Yi-Ly Min, Bo Zhao, Chi-Ping Cheng, Myung-Soo Kang, Shu-Jun Chiu, Elliott Kieff, Chih-Wen Peng
Publikováno v:
Bio-Protocol, Vol 3, Iss 18 (2013)
Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) induces expression of both viral and cellular genes in virus infected B cells by mimicking activated Notch receptors (Notch-IC) that mediate transcription activation through binding to the repressing
Externí odkaz:
https://doaj.org/article/1275b15e24d940fea64205354044cdc2
Autor:
Natali Gulbahce, Han Yan, Amélie Dricot, Megha Padi, Danielle Byrdsong, Rachel Franchi, Deok-Sun Lee, Orit Rozenblatt-Rosen, Jessica C Mar, Michael A Calderwood, Amy Baldwin, Bo Zhao, Balaji Santhanam, Pascal Braun, Nicolas Simonis, Kyung-Won Huh, Karin Hellner, Miranda Grace, Alyce Chen, Renee Rubio, Jarrod A Marto, Nicholas A Christakis, Elliott Kieff, Frederick P Roth, Jennifer Roecklein-Canfield, James A Decaprio, Michael E Cusick, John Quackenbush, David E Hill, Karl Münger, Marc Vidal, Albert-László Barabási
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 6, p e1002531 (2012)
Many human diseases, arising from mutations of disease susceptibility genes (genetic diseases), are also associated with viral infections (virally implicated diseases), either in a directly causal manner or by indirect associations. Here we examine w
Externí odkaz:
https://doaj.org/article/799864a4ab4c4db9b486151cf21f32a5
Autor:
Cheng-Der Liu, Ya-Lin Chen, Yi-Li Min, Bo Zhao, Chi-Ping Cheng, Myung-Soo Kang, Shu-Jun Chiu, Elliott Kieff, Chih-Wen Peng
Publikováno v:
PLoS Pathogens, Vol 8, Iss 12, p e1003084 (2012)
Epstein-Barr Virus (EBV) is an oncogenic γ-herpesvirus that capably establishes both latent and lytic modes of infection in host cells and causes malignant diseases in humans. Nuclear antigen 2 (EBNA2)-mediated transcription of both cellular and vir
Externí odkaz:
https://doaj.org/article/440aed0c64514d2381c380b084d6b62a
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22929 (2011)
Epstein Barr Virus (EBV) replicates in oral epithelial cells and gains entry to B-lymphocytes. In B-lymphocytes, EBV expresses a restricted subset of genes, the Latency III program, which converts B-lymphocytes to proliferating lymphoblasts. Latent M
Externí odkaz:
https://doaj.org/article/b3310293d0794dec990fffccaaea7428
Autor:
Edwin Choy, Roman Yelensky, Sasha Bonakdar, Robert M Plenge, Richa Saxena, Philip L De Jager, Stanley Y Shaw, Cara S Wolfish, Jacqueline M Slavik, Chris Cotsapas, Manuel Rivas, Emmanouil T Dermitzakis, Ellen Cahir-McFarland, Elliott Kieff, David Hafler, Mark J Daly, David Altshuler
Publikováno v:
PLoS Genetics, Vol 4, Iss 11, p e1000287 (2008)
Lymphoblastoid cell lines (LCLs), originally collected as renewable sources of DNA, are now being used as a model system to study genotype-phenotype relationships in human cells, including searches for QTLs influencing levels of individual mRNAs and
Externí odkaz:
https://doaj.org/article/047c23ef1a3046c9b9e8bb7f9e7069bf
Autor:
Yong Du, Jiang Yi He, Mei Ling Chen, Elliott Kieff, Shi Bing Li, Zhi Xin Fang, Benjamin E. Gewurz, Hong Bo Wang, Xiao Dong Dong, Ao Zhang, Qian Zhong, Mu Sheng Zeng, Zhiqiang Zhang, Hua Zhang, Yan Li, Man Zhi Li, Yan Min Liu, Ai Jun Zhou, Yi Xin Zeng, Dan Xiong, Bo Zhao
Publikováno v:
Nature Microbiology. 3:1-8
Epstein-Barr virus (EBV) is causally associated with nasopharyngeal carcinoma, 10% of gastric carcinoma and various B cell lymphomas 1 . EBV infects both B cells and epithelial cells 2 . Recently, we reported that epidermal growth factor and Neuropil