Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Elliott Kagan"'
Autor:
Elliott Kagan, Ji-Hyeon Lee
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 50:713-722
Aerosolized exposure to the chemical warfare vesicant sulfur mustard and its analog nitrogen mustard (HN2) is known to induce airway lesions associated with secretion of proinflammatory cytokines such as IL-6. We have shown recently that HN2 challeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcba9b860c0adee30002476dacf9eb4a
https://doi.org/10.1165/rcmb.2012-0527oc
https://doi.org/10.1165/rcmb.2012-0527oc
Publikováno v:
Toxicology Letters. 185:38-44
The chemical warfare vesicant sulfur mustard (HD) is a known toxic agent to the human respiratory tract and the major airways are considered to be a primary target of HD-induced injury. However, there is no consensus regarding which model systems are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492c91353e2238adf2e3a6ca45311205
https://doi.org/10.1016/j.toxlet.2008.11.015
https://doi.org/10.1016/j.toxlet.2008.11.015
Autor:
Ian MacLachlan, Erik Z. Yu, Joan B. Geisbert, Adam Judge, Amy C.H. Lee, Lloyd Jeffs, Kathleen M. Daddario-DiCaprio, Janet R. Phelps, Elliott Kagan, Lisa E. Hensley, Kevin McClintock, Thomas W. Geisbert, Peter B. Jahrling, Elizabeth A. Fritz
Publikováno v:
The Journal of Infectious Diseases
Background. Ebola virus (EBOV) infection causes a frequently fatal hemorrhagic fever (HF) that is refractory to treatment with currently available antiviral therapeutics. RNA interference represents a powerful, naturally occurring biological strategy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783f8229abf19a2e237a1d169d34fcc5
https://doi.org/10.1086/504267
https://doi.org/10.1086/504267
Autor:
Elliott Kagan
Publikováno v:
Clinics in Laboratory Medicine. 26:421-443
Bioregulators are naturally occurring organic compounds that regulate a multitude of biologic processes. Under natural circumstances, bioregulators are synthesized in minute quantities in a variety of living organisms and are essential for physiologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20a2275fd969a290c88e85357721ef70
https://doi.org/10.1016/j.cll.2006.03.007
https://doi.org/10.1016/j.cll.2006.03.007
Autor:
Heinz Feldmann, Ute Ströher, Allen Grolla, Steven M. Jones, Peter B. Jahrling, Elizabeth A. Fritz, Elliott Kagan, Lisa Fernando, Thomas W. Geisbert, Joan B. Geisbert, Kathleen M. Daddario-DiCaprio, Lisa E. Hensley
Publikováno v:
The Lancet. 367:1399-1404
Summary Background Effective countermeasures are urgently needed to prevent and treat infections caused by highly pathogenic and biological threat agents such as Marburg virus (MARV). We aimed to test the efficacy of a replication-competent vaccine b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d683b5a04e4b17d1f7c81daa2169a75
https://doi.org/10.1016/s0140-6736(06)68546-2
https://doi.org/10.1016/s0140-6736(06)68546-2
Publikováno v:
Brain Research. 1070:24-30
Overactivation of the PI3 kinase/Akt pathway plays an essential role in the development and progression of various tumors. Akt is a key component of this pathway and hyperactivated in different tumors including neuroblastoma and glioma. In the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c041fe054b22cc82f7c591141eb91f
https://doi.org/10.1016/j.brainres.2005.11.041
https://doi.org/10.1016/j.brainres.2005.11.041
Autor:
Elliott Kagan
Publikováno v:
Clinical Pulmonary Medicine. 12:76-83
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f9f9ca4d9373f48b931582dd042130c
https://doi.org/10.1097/01.cpm.0000156700.53793.c5
https://doi.org/10.1097/01.cpm.0000156700.53793.c5
Autor:
Elliott Kagan
Publikováno v:
Journal of Organ Dysfunction. 1:45-56
Ebola virus (EBOV) is a filamentous negative-strand RNA virus with a glycoprotein envelope and comprises four species, Zaire, Sudan, Ivory Coast and Reston. It is a highly lethal pathogen for humans as well as non-human primates, and has been respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fcac9ae29a0902dc2a3febe159db972
https://doi.org/10.1080/14764170500223456
https://doi.org/10.1080/14764170500223456
Autor:
Dana P. Scott, Lisa E. Hensley, Joan B. Geisbert, Howard A. Young, Kelly J. Davis, Elliott Kagan, Tom Larsen, Peter B. Jahrling, Douglas S. Reed, Thomas W. Geisbert
Publikováno v:
The American Journal of Pathology. 163:2347-2370
Ebola virus (EBOV) infection causes a severe and fatal hemorrhagic disease that in many ways appears to be similar in humans and nonhuman primates; however, little is known about the development of EBOV hemorrhagic fever. In the present study, 21 cyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8938cff6b8744825ce1c0e76978e0aa3
https://doi.org/10.1016/s0002-9440(10)63591-2
https://doi.org/10.1016/s0002-9440(10)63591-2
Autor:
Thomas W. Geisbert, Lisa E. Hensley, Elliott Kagan, Kelly J. Davis, Tom Larsen, Howard A. Young, Peter B. Jahrling
Publikováno v:
The American Journal of Pathology. 163:2371-2382
Ebola virus (EBOV) infection causes a severe and often fatal hemorrhagic disease in humans and nonhuman primates. Whether infection of endothelial cells is central to the pathogenesis of EBOV hemorrhagic fever (HF) remains unknown. To clarify the rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab7d9ce7dd94f3f8e5b33e00677b190b
https://doi.org/10.1016/s0002-9440(10)63592-4
https://doi.org/10.1016/s0002-9440(10)63592-4