Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Elliott J. Brecht"'
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Tinnitus is the phantom perception of sound that has no external source. A neurological signature of tinnitus, and the frequently associated hyperacusis, is an imbalance between excitatory and inhibitory activity in the central auditory system (CAS),
Externí odkaz:
https://doaj.org/article/0f63544f12704db1aac11bf3932d80c5
Publikováno v:
Neurobiology of aging. 110
Recent evidence suggests that modulation of the large-conductance, calcium-activated potassium (BK) channel regulates auditory processing in the brain. Because ion channel expression often changes during aging, this could be a factor in age-related h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d8a77478c71fef5484e45e21e9e770
https://pubmed.ncbi.nlm.nih.gov/34861480
https://pubmed.ncbi.nlm.nih.gov/34861480
Publikováno v:
Neurobiology of Aging. 56:87-99
A key feature of age-related hearing loss is a reduction in the expression of inhibitory neurotransmitters in the central auditory system. This loss is partially responsible for changes in central auditory processing, as inhibitory receptive fields p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988afc13486b6969cc5a5fdd9a698496
https://doi.org/10.1016/j.neurobiolaging.2017.04.003
https://doi.org/10.1016/j.neurobiolaging.2017.04.003
Autor:
Jonathan T. Pierce, S. J. Mihic, Ashley E. Philpo, Elliott J. Brecht, Luisa L. Scott, Sangeetha Iyer, N. S. Wu, Richard W. Aldrich, Joseph P. Walton
Publikováno v:
Scientific Reports
Large conductance calcium-activated (BK) channels are broadly expressed in neurons and muscle where they modulate cellular activity. Decades of research support an interest in pharmaceutical applications for modulating BK channel function. Here we re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01325f6e7b444734d7f75c455438ceed
https://doi.org/10.1038/srep42433
https://doi.org/10.1038/srep42433