Difunctionalization of C-C σ-Bonds Enabled by the Reaction of Bicyclo[1.1.0]butyl Boronate Complexes with Electrophiles: Reaction Development, Scope, and Stereochemical Origins

Autor: Alexander Fawcett, Elliott H Denton, Tobias Biberger, Varinder K. Aggarwal, Valerio Fasano, Steven H. Bennett, Nils Winter

Publikováno v: Bennett, S, Fawcett, A, Denton, E, Biberger, T, Fasano, V, Winter, N & Aggarwal, V K 2020, ' Difunctionalization of C–C σ Bonds Enabled by the Reaction of Bicyclo[1.1.0]butyl Boronate Complexes with Electrophiles : Reaction Development, Scope, and Stereochemical Origins ', Journal of the American Chemical Society, vol. 142, no. 39, pp. 16766–16775 . https://doi.org/10.1021/jacs.0c07357
Journal of the American Chemical Society

Difunctionalization reactions of C-C σ bonds have the potential to streamline access to molecules that would otherwise be difficult to prepare. However, the development of such reactions is challenging because C-C σ bonds are typically unreactive.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a167d9e821c4dfd1da568c1b50f8ae7
https://pubmed.ncbi.nlm.nih.gov/32885974

Modular Cyclopentenone Synthesis through the Catalytic Molecular Shuffling of Unsaturated Acid Chlorides and Alkynes

Autor: Yong Ho Lee, Bill Morandi, Elliott H. Denton

Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, 142 (50)

We describe a general strategy for the intermolecular synthesis of polysubstituted cyclopentenones using palladium catalysis. Overall, this reaction is achieved via a molecular shuffling process involving an alkyne, an alpha,beta-unsaturated acid chl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9372e0177e1737e30ceabc7daa8b7d0