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pro vyhledávání: '"Elliott Gorfain"'
Autor:
Lori Allison Kohlstaedt, James Williams, Elliott Gorfain, Guang X. Luo, Linguang Cao, Catherine Helen Charles, Ianessa Morantte, Fang Fang
Publikováno v:
Antimicrobial Agents and Chemotherapy. 47:1503-1508
We have developed a technology for improving avidity by making bivalent, trivalent, or tetravalent recombinant polypeptides. We designed tripartite proteins consisting of the Fab fragment of an antibody fused with a hinge derived from human immunoglo
Autor:
Lori Allison Kohlstaedt, Ianessa Morantte, James Williams, Elliott Gorfain, Fang Fang, Catherine Helen Charles, Guang X. Luo
Publikováno v:
Journal of immunological methods. 275(1-2)
The monoclonal antibody 1A6 binds to human intercellular adhesion molecule 1 (ICAM-1, CD54) and inhibits infection by 90% of human rhinovirus (HRV) serotypes. To make a therapeutic molecule for preventing and treating HRV infection, we humanized a si