Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Elliott Ferris"'
Autor:
Stephanie N. Kravitz, Elliott Ferris, Michael I. Love, Alun Thomas, Aaron R. Quinlan, Christopher Gregg
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111945- (2023)
Summary: Genes are typically assumed to express both parental alleles similarly, yet cell lines show random allelic expression (RAE) for many autosomal genes that could shape genetic effects. Thus, understanding RAE in human tissues could improve our
Externí odkaz:
https://doaj.org/article/7414b2bb9d974791a9b3a4454eb8bc00
Autor:
Paul J. Bonthuis, Susan Steinwand, Cornelia N. Stacher Hörndli, Jared Emery, Wei-Chao Huang, Stephanie Kravitz, Elliott Ferris, Christopher Gregg
Publikováno v:
Cell Reports, Vol 38, Iss 10, Pp 110500- (2022)
Summary: Noncanonical genomic imprinting can cause biased expression of one parental allele in a tissue; however, the functional relevance of such biases is unclear. To investigate ethological roles for noncanonical imprinting in dopa decarboxylase (
Externí odkaz:
https://doaj.org/article/80e897921e7743a7b88649d4a8a36b5e
Publikováno v:
Cell Reports, Vol 22, Iss 10, Pp 2742-2755 (2018)
Summary: The identity of most functional elements in the mammalian genome and the phenotypes they impact are unclear. Here, we perform a genome-wide comparative analysis of patterns of accelerated evolution in species with highly distinctive traits t
Externí odkaz:
https://doaj.org/article/1c6eb0e6f5a745c48768ca0a0d0959f6
Autor:
Elliott Ferris, Christopher Gregg
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2608-2620.e4 (2019)
Summary: Obesity is a clinical problem and an important adaptation in many species. Hibernating mammals, for example, become obese, insulin resistant, and hyperinsulinemic to store fat. Here, we combine comparative phylogenomics with large-scale huma
Externí odkaz:
https://doaj.org/article/d511e70f56314027827ee581313c7e86
Autor:
Cornelia N. Stacher Hörndli, Eleanor Wong, Elliott Ferris, Kathleen Bennett, Susan Steinwand, Alexis Nikole Rhodes, P. Thomas Fletcher, Christopher Gregg
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1814-1829.e6 (2019)
Summary: Complex ethological behaviors could be constructed from finite modules that are reproducible functional units of behavior. Here, we test this idea for foraging and develop methods to dissect rich behavior patterns in mice. We uncover discret
Externí odkaz:
https://doaj.org/article/ae473bd1c8354bfe885affe728501c22
Autor:
Paul J. Bonthuis, Wei-Chao Huang, Cornelia N. Stacher Hörndli, Elliott Ferris, Tong Cheng, Christopher Gregg
Publikováno v:
Cell Reports, Vol 12, Iss 6, Pp 979-991 (2015)
Here, we describe an RNA-sequencing (RNA-seq)-based approach that accurately detects even modest maternal or paternal allele expression biases at the tissue level, which we call noncanonical genomic imprinting effects. We profile imprinting in the ar
Externí odkaz:
https://doaj.org/article/a73cc39bc4e043ac9de2fb1698489876
Autor:
Emily DiBlasi, Douglas Gray, Andrey A. Shabalin, Qingqin S. Li, W. Brandon Callor, Anne V. Kirby, Nicola J. Camp, Ken R. Smith, Elliott Ferris, Anna R. Docherty, Michael Klein, Eoin Gaj, Eric T. Monson, Hilary Coon, Eli A. Stahl, Brooks R. Keeshin, Nancy William, Amanda V. Bakian, Zhe Yu, Leslie Jerominski, Danli Chen, Alison Fraser, Erik Christensen
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 186:508-520
Identification of genetic factors leading to increased risk of suicide death is critical to combat rising suicide rates, however, only a fraction of the genetic variation influencing risk has been accounted for. To address this limitation, we conduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84330c64e1e8fb7fcbc82de57766dcc6
https://doi.org/10.1002/ajmg.b.32861
https://doi.org/10.1002/ajmg.b.32861
Autor:
Carlo C. Maley, Amy M. Boddy, Abegglen Lisa M, Marc Tollis, Shawn M. Rupp, Christina Athena Aktipis, Elliott Ferris, Joshua D Schiffman, Michael M Garner, Valerie Harris, Michael S. Campbell, Wendy K. Kiso, Dennis L. Schmitt, Tara M. Harrison, Mark Yandell, Christopher Gregg
Publikováno v:
Molecular biology and evolution, vol 38, iss 9
Molecular Biology and Evolution
Molecular Biology and Evolution
Disease susceptibility and resistance are important factors for the conservation of endangered species, including elephants. We analyzed pathology data from 26 zoos and report that Asian elephants have increased neoplasia and malignancy prevalence co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a78bc5b2dde32d437909b04ed8014c5
https://escholarship.org/uc/item/9tm6f41s
https://escholarship.org/uc/item/9tm6f41s
Autor:
P. Thomas Fletcher, Eleanor Wong, Elliott Ferris, Alexis Nikole Rhodes, Kathleen Bennett, Christopher Gregg, Susan Steinwand, Cornelia N. Stacher Hörndli
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1814-1829.e6 (2019)
Cell reports
Cell reports
SUMMARY Complex ethological behaviors could be constructed from finite modules that are reproducible functional units of behavior. Here, we test this idea for foraging and develop methods to dissect rich behavior patterns in mice. We uncover discrete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7768ae909feda31f697f5749cbc0f405
http://www.sciencedirect.com/science/article/pii/S2211124719309350
http://www.sciencedirect.com/science/article/pii/S2211124719309350
Autor:
Cornelia N. Stacher Hörndli, Jared Emery, Wei-Chao Huang, Elliott Ferris, Stephanie N Kravitz, Susan Steinwand, Paul J Bonthuis, Christopher Gregg
SUMMARYDopa decarboxylase (DDC) regulates the synthesis of monoaminergic neurotransmitters and is linked to psychiatric and metabolic disorders. Ddc exhibits complex genomic imprinting effects that have not been functionally studied. Here, we investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19274352089bdb7951cdf8aa94b96a0d
https://doi.org/10.1101/2020.06.23.168195
https://doi.org/10.1101/2020.06.23.168195