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Encapsulation-free controlled release: Electrostatic adsorption eliminates the need for protein encapsulation in PLGA nanoparticles.

Autor: Pakulska MM; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario M5S 3E5, Canada.; Institute for Biomaterials and Biomedical Engineering, University of Toronto, Ontario M5S 3G9, Canada., Elliott Donaghue I; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario M5S 3E5, Canada.; Institute for Biomaterials and Biomedical Engineering, University of Toronto, Ontario M5S 3G9, Canada., Obermeyer JM; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario M5S 3E5, Canada.; Institute for Biomaterials and Biomedical Engineering, University of Toronto, Ontario M5S 3G9, Canada., Tuladhar A; Institute for Biomaterials and Biomedical Engineering, University of Toronto, Ontario M5S 3G9, Canada., McLaughlin CK; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario M5S 3E5, Canada., Shendruk TN; The Rudolf Peierls Centre for Theoretical Physics, University of Oxford, Oxford OX1 3NP, UK., Shoichet MS; Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Ontario M5S 3E5, Canada.; Institute for Biomaterials and Biomedical Engineering, University of Toronto, Ontario M5S 3G9, Canada.; Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada.

Publikováno v: Science advances [Sci Adv] 2016 May 27; Vol. 2 (5), pp. e1600519. Date of Electronic Publication: 2016 May 27 (Print Publication: 2016).