Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Elliott D. Crouser"'
Autor:
Sonal Pannu, Matthew C. Exline, Joseph S. Bednash, Joshua A. Englert, Philip Diaz, Amy Bartlett, Guy Brock, Qing Wu, Ian C. Davis, Elliott D. Crouser
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background The SARS CoV-2 pandemic has resulted in more than 1.1 million deaths in the USA alone. Therapeutic options for critically ill patients with COVID-19 are limited. Prior studies showed that post-infection treatment of influenza A vi
Externí odkaz:
https://doaj.org/article/fc131bcd0a20424797031923f0d1a0a8
Autor:
Elliot Offman, Noopur Singh, Mark W. Julian, Landon W. Locke, Sabahattin Bicer, Jonah Mitchell, Thomas Matthews, Kirsten Anderson, Elliott D. Crouser
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Sarcoidosis is a chronic, multisystem inflammatory disorder characterized by non-caseating epithelioid granulomas; infiltration of mononuclear cells; and destruction of microarchitecture in the skin, eye, heart, and central nervous system
Externí odkaz:
https://doaj.org/article/d001686bf0c047ae87991b877123b4e5
Autor:
Sonal R. Pannu, MD, MSc, Matthew Exline, MD, MPH, Brett Klamer, MS, Guy Brock, PhD, Elliott D. Crouser, MD, John W. Christman, MD, Philip Diaz, MD
Publikováno v:
Critical Care Explorations, Vol 4, Iss 6, p e0704 (2022)
OBJECTIVES:. Timely regulation of oxygen (Fio2) is essential to prevent hyperoxemia or episodic hypoxemia. Exposure to excessive Fio2 is often noted early after onset of mechanical ventilation. In this pilot study, we examined the feasibility, safety
Externí odkaz:
https://doaj.org/article/f1b680c749b441598f59ef70297b527f
Autor:
Nancy G. Casanova, Manuel L. Gonzalez-Garay, Belinda Sun, Christian Bime, Xiaoguang Sun, Kenneth S. Knox, Elliott D. Crouser, Nora Sammani, Taylor Gonzales, Bhupinder Natt, Sachin Chaudhary, Yves Lussier, Joe G. N. Garcia
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Rationale Despite the availability of multi-“omics” strategies, insights into the etiology and pathogenesis of sarcoidosis have been elusive. This is partly due to the lack of reliable preclinical models and a paucity of validated biomar
Externí odkaz:
https://doaj.org/article/6f8367a8d1a643198912320ea5f02edf
Autor:
Elliott D. Crouser, Joseph E. Parrillo, Greg S. Martin, David T. Huang, Pierre Hausfater, Ilya Grigorov, Diana Careaga, Tiffany Osborn, Mohamad Hasan, Liliana Tejidor
Publikováno v:
Journal of Intensive Care, Vol 8, Iss 1, Pp 1-10 (2020)
Abstract Background The initial presentation of sepsis in the emergency department (ED) is difficult to distinguish from other acute illnesses based upon similar clinical presentations. A new blood parameter, a measurement of increased monocyte volum
Externí odkaz:
https://doaj.org/article/c6e4612256e748909bd114a156306281
Autor:
Gregory J. Eisinger, MD, MSSW, Wissam Osman, BS, Evan R. Prather, BS, Mark W. Julian, MS, Mikhail A. Gavrilin, PhD, Elliott D. Crouser, MD, Mark D. Wewers, MD
Publikováno v:
Critical Care Explorations, Vol 4, Iss 2, p e0631 (2022)
OBJECTIVES:. Increased monocyte distribution width (MDW) has recently been shown to be a reliable indicator of early sepsis detection. This study therefore sought to determine if inflammasome activation can be linked to monocyte size changes in sepsi
Externí odkaz:
https://doaj.org/article/580ea3e2caa841c598066c52471edd94
Publikováno v:
ERJ Open Research, Vol 8, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/ff991181dd144f038a9fcb7a7ef437dd
Publikováno v:
Contemporary Clinical Trials Communications, Vol 20, Iss , Pp 100669- (2020)
Introduction: Sarcoidosis is a systemic granulomatous disease of unknown cause afflicting young to middle-aged adults. The majority of patients with active pulmonary sarcoidosis complain of overwhelming fatigue, which often persists despite administr
Externí odkaz:
https://doaj.org/article/7d5072811fd64af795a47c56faa8c1b5
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The inability to effectively model sarcoidosis in the laboratory or in animals continues to hinder the discovery and translation of new, targeted treatments. The granuloma is the signature pathological hallmark of sarcoidosis, yet there are significa
Externí odkaz:
https://doaj.org/article/c1327de165414870a3443b3f3a519adf
Autor:
Franck F. Rahaghi, Robert P. Baughman, Lesley Ann Saketkoo, Nadera J. Sweiss, Joseph B. Barney, Surinder S. Birring, Ulrich Costabel, Elliott D. Crouser, Marjolein Drent, Alicia K. Gerke, Jan C. Grutters, Nabeel Y. Hamzeh, Isham Huizar, W. Ennis James, Sanjay Kalra, Susanna Kullberg, Huiping Li, Elyse E. Lower, Lisa A. Maier, Mehdi Mirsaeidi, Joachim Müller-Quernheim, Eva M. Carmona Porquera, Lobelia Samavati, Dominique Valeyre, Mary Beth Scholand
Publikováno v:
European Respiratory Review, Vol 29, Iss 155 (2020)
Pulmonary sarcoidosis presents substantial management challenges, with limited evidence on effective therapies and phenotypes. In the absence of definitive evidence, expert consensus can supply clinically useful guidance in medicine. An international
Externí odkaz:
https://doaj.org/article/043ed6e1efc84e9abb8d841c706b537f