Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Elliott Chum"'
Autor:
Elliott Chum, Adeera Levin, William A. Gourlay, Ada W.Y. Chung, Genevieve Brin, Jong Moo Kim, H.H. Clarice Yang, Mhairi K. Sigrist
Publikováno v:
Nephrology Dialysis Transplantation. 25:4031-4041
Background. Abnormalities of vascular function and accumulation of oxidative stress have been associated with chronic kidney disease (CKD). Dialysis modalities, peritoneal dialysis (PD) and haemodialysis (HD) may differentially impact on vascular fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a59284121564d5f29ce81b3488f8b258
https://doi.org/10.1093/ndt/gfq202
https://doi.org/10.1093/ndt/gfq202
Publikováno v:
British Journal of Pharmacology. 158:1503-1512
Background and purpose: During development of thoracic aortic aneurysms in a mouse model of Marfan syndrome, upregulation of matrix metalloproteinase (MMP)-2 and -9 was accompanied by compromised aortic constriction and endothelium-dependent relaxati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e6364657c0634dd4cc96cb391821541
https://doi.org/10.1111/j.1476-5381.2009.00443.x
https://doi.org/10.1111/j.1476-5381.2009.00443.x
Autor:
Elliott Chum, Anthony D. Booth, Adeera Levin, Ada W.Y. Chung, H.H. Clarice Yang, Mhairi K. Sigrist, William A. Gourlay
Publikováno v:
Journal of Vascular Research. 47:128-138
We hypothesized that there was differential vasomotor dysfunction in the microcirculation between nondialyzed and dialyzed chronic kidney disease (CKD) patients. During live donor kidney transplantation procedures, skin arterioles (SkA; internal diam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9698c27512b70996345c267c03795857
https://doi.org/10.1159/000235967
https://doi.org/10.1159/000235967
Publikováno v:
European Journal of Pharmacology. 613:114-118
Diabetes is associated with a perturbation of signaling pathways in vascular tissue, which causes vasomotor dysfunction such as hypertension. We have previously demonstrated that vessels from diabetic patients were more contractile than those from no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f386846104eb4cf2e5b398b0bb977493
https://doi.org/10.1016/j.ejphar.2009.04.029
https://doi.org/10.1016/j.ejphar.2009.04.029
Autor:
Şerife Yalçın, Elliott Chum, X. Chris Le, Jie Wu, Robert J. Audette, Xue Zhang, Christopher J. Martin, Tee L. Guidotti, Chaoke Liang, Baoshan Yuan
Publikováno v:
American Journal of Industrial Medicine. 35:574-580
Background: Inhalational exposure to zinc oxide fumes is associated with metal fume fever a self-limited but very uncomfortable condition closely resembling influenza. Very little is known regarding the toxicokinetics of inhaled zinc, making the inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a36cbffade04d96cf3891df03e2482b
https://doi.org/10.1002/(sici)1097-0274(199906)35:6<574::aid-ajim4>3.0.co
https://doi.org/10.1002/(sici)1097-0274(199906)35:6<574::aid-ajim4>3.0.co
Publikováno v:
British journal of pharmacology. 158(6)
During development of thoracic aortic aneurysms in a mouse model of Marfan syndrome, upregulation of matrix metalloproteinase (MMP)-2 and -9 was accompanied by compromised aortic constriction and endothelium-dependent relaxation. Losartan has been pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc2487786286c0d0631c8135b75cdd72
https://pubmed.ncbi.nlm.nih.gov/19814725
https://pubmed.ncbi.nlm.nih.gov/19814725
Autor:
Elliott Chum, Mhairi K. Sigrist, Ada W.Y. Chung, Adeera Levin, Jong Moo Kim, H.H. Clarice Yang, William A. Gourlay
Publikováno v:
Circulation. 120(9)
Background— Cardiovascular disease is the leading cause of mortality in chronic kidney disease patients on maintenance dialysis. Given the importance of matrix metalloproteinase-2 (MMP-2) in matrix integrity, vascular cell function, and structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21d9065e0209ccb3a72eddc8cb02cb8
https://pubmed.ncbi.nlm.nih.gov/19687355
https://pubmed.ncbi.nlm.nih.gov/19687355
Autor:
H.H. Clarice Yang, Adeera Levin, Genevieve Brin, Ada W.Y. Chung, William A. Gourlay, Elliott Chum, Mhairi K. Sigrist
Publikováno v:
Cardiovascular research. 84(3)
Aims Chronic kidney disease (CKD) and diabetes are the prominent risk factors of cardiovascular disease (CVD). Matrix metalloproteinase (MMP)-2 and -9 regulate vascular structure by degrading elastic fibre and inhibit angiogenesis by generating angio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7778a257a83afac6b0ee0235f2ea218
https://pubmed.ncbi.nlm.nih.gov/19617223
https://pubmed.ncbi.nlm.nih.gov/19617223
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. (2):305-312.e2
Objective Losartan potassium (INN losartan), an antihypertensive drug, has been shown to prevent thoracic aortic aneurysm in Marfan syndrome through the inhibition of transforming growth factor β. Recently we reported that doxycycline, a nonspecific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5aab362710a90da87ea28c1409f8fe2