Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Elliot T. Rosen"'
Autor:
Kaytee L. Pokrzywinski, Thomas G. Biel, Elliot T. Rosen, Julia L. Bonanno, Baikuntha Aryal, Francesca Mascia, Delaram Moshkelani, Steven Mog, V. Ashutosh Rao
Publikováno v:
Biology of Sex Differences, Vol 9, Iss 1, Pp 1-17 (2018)
Abstract Background Doxorubicin (DOX), an anthracycline therapeutic, is widely used to treat a variety of cancer types and known to induce cardiomyopathy in a time and dose-dependent manner. Postmenopausal and hypertensive females are two high-risk g
Externí odkaz:
https://doaj.org/article/e079b32ae31b427b80589dfdcb260e8d
Publikováno v:
Health Physics. 119:12-20
The aim of this study was to analyze the changes in mouse jejunum protein expression in response to prophylactic administration of two promising tocols, γ-tocotrienol (GT3) and α-tocopherol succinate (TS), as radiation countermeasures before irradi
Autor:
Leena M. Chehab, Yanira Gonzalez, Jennifer S. Dickey, Elliot T. Rosen, Dmitry Kryndushkin, V. Ashutosh Rao, Baikuntha Aryal
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0233967 (2020)
PLoS ONE
PLoS ONE
Radiation-induced heart disease presents a significant challenge in the event of an accidental radiation exposure as well as to cancer patients who receive acute doses of irradiation as part of radiation therapy. We utilized the spontaneously hyperte
Autor:
Yanira Gonzalez, V. Ashutosh Rao, Leena Chehab, Baikuntha Aryal, Dmitry Kryndushkin, Elliot T. Rosen, Jennifer Dickey
Publikováno v:
Cancer Research. 80:5352-5352
Radiation-induced heart disease represents a significant health risk in the event of an accidental radiation exposure as well as to cancer patients who receive acute doses of irradiation as part of radiation therapy. We utilized the Wistar-Kyoto and
Autor:
Elliot T. Rosen, Thomas G. Biel, Delaram Moshkelani, Julia L. Bonanno, Kaytee L. Pokrzywinski, Francesca Mascia, Baikuntha Aryal, V. Ashutosh Rao, Steven R. Mog
Publikováno v:
Biology of Sex Differences
Biology of Sex Differences, Vol 9, Iss 1, Pp 1-17 (2018)
Biology of Sex Differences, Vol 9, Iss 1, Pp 1-17 (2018)
Background Doxorubicin (DOX), an anthracycline therapeutic, is widely used to treat a variety of cancer types and known to induce cardiomyopathy in a time and dose-dependent manner. Postmenopausal and hypertensive females are two high-risk groups for
Autor:
Elliot T. Rosen, V. Ashutosh Rao, Kaytee L. Pokrzywinski, Baikuntha Aryal, Carrie L. Moland, Jennifer S. Dickey, Yanira Gonzalez, Leena M. Chehab, Vikrant Vijay, Steven R. Mog, Varsha G. Desai
Publikováno v:
Cancer Chemotherapy and Pharmacology. 76:447-459
Chemotherapy with doxorubicin (Dox) causes dose-limiting cardiotoxicity. We investigated the role that gender has on cardiosensitivity to Dox treatment by evaluating reproductive hormone levels in male, castrated male (c-male), female and ovariectomi
Autor:
Yanira Gonzalez, V. Ashutosh Rao, Elliot T. Rosen, Leena Chehab, Dmitry Kryndushkin, Jennifer Dickey, Steven R. Mog, Baikuntha Aryal
Publikováno v:
Cancer Research. 79:3940-3940
Radiation-induced heart disease presents a significant challenge in the event of an accidental radiation exposure as well as to cancer patients who receive acute doses of irradiation as part of radiation therapy. We utilized the Wistar-Kyoto and spon
Autor:
John Todd, Quynh Anh Lu, Joel Estis, Brian B. Hasinoff, Steven E. Lipshultz, Jun Zhang, Barry A. Rosenzweig, Sara J. Agee, Elliot T. Rosen, Karol L. Thompson, Alan Knapton, Eugene H. Herman
Publikováno v:
Toxicologic Pathology. 39:1091-1106
Cardiotoxicity was an unanticipated side effect elicited by the clinical use of imatinib (Imb). This toxicity has been examined in only a limited number of experimental studies. The present study sought, by a variety of approaches, to identify import
Autor:
John Todd, Eugene H. Herman, Elliot T. Rosen, Sara J. Agee, Steven E. Lipshultz, Jun Zhang, Alan Knapton, Joel Estis, Quynh Anh Lu
Publikováno v:
Toxicologic Pathology. 39:653-663
Cardiac troponins have proved to be reliable blood biomarkers for identifying a variety of myocardial alterations in humans and animals. Recently, an ultrasensitive cTnI assay (Erenna IA) has been used to demonstrate increases in baseline cTnI result
Autor:
Elliot T. Rosen, Leena Chehab, Yanira Gonzalez, V. Ashutosh Rao, Jennifer Dickey, Steven R. Mog, Baikuntha Aryal, Dmitry Kryndushkin
Publikováno v:
Cancer Research. 78:845-845
Radiation-induced heart disease (RIHD) presents a significant challenge in the oncology setting. For instance, patients receiving acute doses of irradiation to the thoracic cavity for Hodgkin's lymphoma or breast cancer are subject to an elevated ris