Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Elliot Medina"'
Autor:
Qianqian Ming, Daniel Antfolk, David A. Price, Anna Manturova, Elliot Medina, Srishti Singh, Charlotte Mason, Timothy H. Tran, Keiran S. M. Smalley, Daisy W. Leung, Vincent C. Luca
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The immune checkpoint protein, Lymphocyte activation gene-3 (LAG3), binds Major Histocompatibility Complex Class II (MHC-II) and suppresses T cell activation. Despite the recent FDA approval of a LAG3 inhibitor for the treatment of melanoma,
Externí odkaz:
https://doaj.org/article/7b12d9f7a4494fceb98b9a25a6dc0b12
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Fat and Dachsous are large cadherins that regulate planar polarity as a receptor:ligand pair. Here, authors determine the structure of the Fat:Dachsous complex to uncover the molecular determinants of binding and posttranslational modification.
Externí odkaz:
https://doaj.org/article/26c914ba27a3409fbe4efea1685f878a
Autor:
Gregory Watson, Daniel Lester, Hui Ren, Connor M. Forsyth, Elliot Medina, David Gonzalez Perez, Lancia Darville, Jiqiang Yao, Vince Luca, John Koomen, Ling Cen, Eric Lau
Publikováno v:
Cells, Vol 10, Iss 6, p 1310 (2021)
Alterations in genes encoding for proteins that control fucosylation are known to play causative roles in several developmental disorders, such as Dowling-Degos disease 2 and congenital disorder of glycosylation type IIc (CDGIIc). Recent studies have
Externí odkaz:
https://doaj.org/article/9c3d552b38d54a819d2aac9602abe5b4
Autor:
David Gonzalez-Perez, Satyajit Das, Daniel Antfolk, Hadia S. Ahsan, Elliot Medina, Carolyn E. Dundes, Rayyan T. Jokhai, Emily D. Egan, Stephen C. Blacklow, Kyle M. Loh, Paulo C. Rodriguez, Vincent C. Luca
Publikováno v:
Nature Chemical Biology. 19:9-17
Autor:
Eleonora Pelle, Mauro Cives, Elliot Medina, Charlotte C. Mason, Sebastian A. Snedal, Xiomar E. Bustos-Perez, Leticia Tordesillas, Fontela Miguel Gomez, Rossetti Renata A. Marques, Gabriele Maiorano, Vince Luca, Patrick Hwu, Daniel Abate-Daga, Jonathan Strosberg
Publikováno v:
Endocrine Abstracts.
Autor:
Eleonora Pelle, Mauro Cives, Elliot Medina, Charlotte Mason, Sebastian Snedal, Xiomar Bustos Perez, Leticia Tordesillas, Miguel Gomez Fontela, Renata Rossetti, Gabriele Maiorano, Vincent Luca, Patrick Hwu, Daniel Abate-Daga, Jonathan Strosberg
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
David Gonzalez-Perez, Satyajit Das, Elliot Medina, Daniel Antfolk, Emily D. Egan, Stephen C. Blacklow, Paulo C. Rodriguez, Vincent C. Luca
The Notch pathway regulates cell fate decisions and is an emerging target for regenerative and cancer therapies. Recombinant Notch ligands are attractive candidates for modulating Notch signaling; however, their intrinsically low receptor-binding aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d56f7802f8a195fb40d1e0d31e7ea2b
https://doi.org/10.1101/2022.03.07.483330
https://doi.org/10.1101/2022.03.07.483330
Autor:
Eric Lau, Hui Ren, Lancia Darville, Connor M Forsyth, Elliot Medina, Ling Cen, John M. Koomen, Gregory W. Watson, Vince Luca, Jiqiang Yao, David Gonzalez Perez, Daniel K. Lester
Publikováno v:
Cells
Cells, Vol 10, Iss 1310, p 1310 (2021)
Volume 10
Issue 6
Cells, Vol 10, Iss 1310, p 1310 (2021)
Volume 10
Issue 6
Simple Summary Dysregulated fucosylation has been characterized as an underlying cause or a contributor to the pathogenesis of several disease states. However, to date, there is not a clear understanding of how and what proteins, signaling pathways,