An Insight into Functional Metagenomics: A High-Throughput Approach to Decipher Food–Microbiota–Host Interactions in the Human Gut

Autor: Elliot Mathieu, Véronique Léjard, Chaima Ezzine, Pauline Govindin, Aurélien Morat, Margot Giat, Nicolas Lapaque, Joël Doré, Hervé M. Blottière

Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 24, p 17630 (2023)

Our understanding of the symbiotic relationship between the microbiota and its host has constantly evolved since our understanding that the “self” was not only defined by our genetic patrimony but also by the genomes of bugs living in us. The fir

Externí odkaz: https://doaj.org/article/fde9e0397c9841e5a0997cd1092f4f59

Oral Primo-Colonizing Bacteria Modulate Inflammation and Gene Expression in Bronchial Epithelial Cells

Autor: Elliot Mathieu, Chad W. MacPherson, Jocelyn Belvis, Olivier Mathieu, Véronique Robert, Vinciane Saint-Criq, Philippe Langella, Thomas A. Tompkins, Muriel Thomas

Publikováno v: Microorganisms, Vol 8, Iss 8, p 1094 (2020)

The microbiota of the mouth disperses into the lungs, and both compartments share similar phyla. Considering the importance of the microbiota in the maturation of the immunity and physiology during the first days of life, we hypothesized that primo-c

Externí odkaz: https://doaj.org/article/aaacf0823b2d448c811f0a3d0a65b0cf

The microbiota plays a critical role in the reactivity of lung immune components to innate ligands

Autor: Aude Remot, Elliot Mathieu, Daphné Laubreton, Carole Drajac, Delphyne Descamps, Sabine Riffault, Muriel Thomas, Quentin Marquant, Edwige Bouguyon, Marie-Louise Noordine

Publikováno v: FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (4), 15 p. ⟨10.1096/fj.202002338R⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (4), ⟨10.1096/fj.202002338R⟩

The microbiota contributes to shaping efficient and safe immune defenses in the gut. However, little is known about the role of the microbiota in the education of pulmonary innate immune responses. Here, we tested whether the endogenous microbiota ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c224ec3bbb4d0238072d27c11116cb96
https://hal.inrae.fr/hal-03169721

Microbiota educates innate immune response to Toll-like receptors stimulation and RSV infection in lung

Autor: Quentin Marquant, Aude Remot, Sabine Riffault, Daphné Laubreton, Marie-Louise Noordine, Elliot Mathieu, Carole Drajac, Muriel Thomas, Delphyne Descamps

Publikováno v: Respiratory infections.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acd9ca88d9dd470c9a1682fe8a98e761
https://doi.org/10.1183/13993003.congress-2019.oa5144

Paradigms of Lung Microbiota Functions in Health and Disease, Particularly, in Asthma

Autor: Aude Remot, Delphyne Descamps, Sabine Riffault, Muriel Thomas, Claire Cherbuy, Philippe Langella, Unai Escribano-Vazquez, Elliot Mathieu

Publikováno v: Frontiers in Physiology, Vol 9 (2018)
Frontiers in Physiology
Frontiers in Physiology, Frontiers, 2018, 9, pp.1-11. ⟨10.3389/fphys.2018.01168⟩
Frontiers in Physiology (9), 1-11. (2018)

International audience; Improvements in our knowledge of the gut microbiota have broadened our vision of the microbes associated with the intestine. These microbes are essential actors and protectors of digestive and extra-digestive health and, by ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f53b244b1772392f4965fbb15c636fc
https://www.frontiersin.org/article/10.3389/fphys.2018.01168/full