Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Elliot Gild"'
Autor:
Cory T. Reidl, Tahirah K. Heath, Iman Darwish, Rachel M. Torrez, Maxwell Moore, Elliot Gild, Boguslaw P. Nocek, Anna Starus, Richard C. Holz, Daniel P. Becker
Publikováno v:
Antibiotics, Vol 9, Iss 9, p 595 (2020)
Inhibitors of the bacterial enzyme dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE; EC 3.5.1.18) hold promise as antibiotics with a new mechanism of action. Herein we describe the discovery of a new series of indoline sulfonamide
Externí odkaz:
https://doaj.org/article/a098c382d39a4dc9b420906e26c19a56
Autor:
Richard C. Holz, Thahani S. Habeeb Mohammad, Matthew Kochert, Boguslaw Nocek, Tahirah K. Heath, Kenneth W. Olsen, Elliot Gild, Kaitlyn Lovato, Daniel P. Becker
Publikováno v:
Biochemistry. 60(12)
We report the atomic-resolution (1.3 A) X-ray crystal structure of an open conformation of the dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE, EC 3.5.1.18) from Neisseria meningitidis. This structure [Protein Data Bank (PDB) entr
Autor:
Anna Starus, Maxwell Moore, Elliot Gild, Tahirah K. Heath, Iman Darwish, Rachel M Torrez, Cory T. Reidl, Daniel P. Becker, Richard C. Holz, Boguslaw Nocek
Publikováno v:
Antibiotics, Vol 9, Iss 595, p 595 (2020)
Antibiotics
Volume 9
Issue 9
Antibiotics
Volume 9
Issue 9
Inhibitors of the bacterial enzyme dapE-encoded N-succinyl-l,l-diaminopimelic acid desuccinylase (DapE
EC 3.5.1.18) hold promise as antibiotics with a new mechanism of action. Herein we describe the discovery of a new series of indoline sulfonam
EC 3.5.1.18) hold promise as antibiotics with a new mechanism of action. Herein we describe the discovery of a new series of indoline sulfonam