Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Elliot D. Rosen"'
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 6, p e1003095 (2013)
Thromboembolic disease is a leading cause of morbidity and mortality worldwide. In the last several years there have been a number of studies attempting to identify mechanisms that stop thrombus growth. This paper identifies a novel mechanism related
Externí odkaz:
https://doaj.org/article/76ec3e7e41a74d47b7ff6f43b7025e27
Autor:
Katharine Bisordi, Elliot D. Rosen, Christopher R. Sweet, Santanu Chatterjee, Zhiliang Xu, Mark Alber
Publikováno v:
Journal of The Royal Society Interface. 8:1760-1771
In this paper, a new three-dimensional modelling approach is described for studying fluid–viscoelastic cell interaction, the subcellular element Langevin (SCEL) method, with cells modelled by subcellular elements (SCEs) and SCE cells coupled with f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6675d9c80a2fa56d739d54c3e7e207b
https://doi.org/10.1098/rsif.2011.0180
https://doi.org/10.1098/rsif.2011.0180
Autor:
Gangaraju Rajashekhar, William R. Wolter, Elliot D. Rosen, Abby Marin, Malgorzata M. Kamocka, Aravind Sanjeevaiah, Mark A. Suckow, Sunil Badve, Matthias Clauss, Kevin Pumiglia
Publikováno v:
Scopus-Elsevier
Chronic inflammation is tightly linked to diseases associated with endothelial dysfunction including aberrant angiogenesis. To better understand the endothelial role in pro-inflammatory angiogenesis, we analyzed signaling pathways in continuously act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcda2ad120c0509a7ae31251580993bd
https://doi.org/10.1002/jcp.22404
https://doi.org/10.1002/jcp.22404
Publikováno v:
Transgenic Research. 17:979-983
The random germline integration of genetically engineered transgenes has been a powerful technique to study the role of particular genes in variety of biological processes. Although the identification of the transgene insertion site is often not esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f28f1a55c536e4c3bcdd625bdb14ca
https://doi.org/10.1007/s11248-008-9190-7
https://doi.org/10.1007/s11248-008-9190-7
Autor:
Elliot D. Rosen, Mark A. Suckow
Publikováno v:
Journal of Organ Dysfunction. 3:143-149
A variety of diseases, including some which affect the hemostatic and blood coagulation systems, result from dysfunction of specific cell types. Attempts to ameliorate such diseases by implantation of healthy donor cells typically fail due to immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c2983d669c85d3302c159864b33565d
https://doi.org/10.1080/17471060601137464
https://doi.org/10.1080/17471060601137464
Autor:
Morris Pollard, Elliot D. Rosen, Zhong Liang, William A. Wolter, Julie E. Heinrich, Hui Song, Mark A. Suckow
Publikováno v:
Cancer Immunology, Immunotherapy. 56:725-730
Reducing expression of the tissue factor gene in prostate adenocarcinoma cells (PAIII) results in a cell line that, in vivo, mimics the growth of wildtype (wt) PAIII. However, instead of continuing to grow and metastasize as wt PAIII tumors do, tissu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a3143d3117a40403f0d911398bead6
https://doi.org/10.1007/s00262-006-0223-x
https://doi.org/10.1007/s00262-006-0223-x
Autor:
Michelle E. Casad, Mark A. Suckow, Elliot D. Rosen, Francis J. Castellino, Julie Roahrig, Ivo Cornelissen, Amy Zollman
Publikováno v:
Experimental Biology and Medicine. 230:860-864
Transplantation of hepatic stem cells in utero has been advanced as a potential clinical approach to a variety of diseases, including deficiencies of coagulation factors. Although syngeneic transplantation has met with some success, consideration nee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15e94db0197fb6311f91933a345f619c
https://doi.org/10.1177/153537020523001111
https://doi.org/10.1177/153537020523001111
Publikováno v:
Journal of Clinical Investigation. 115:1552-1561
Anticoagulant protein C (PC) is important not only for maintenance of normal hemostasis, but also for regulating the host immune response during inflammation. Because mice with a designed total genetic deficiency in PC (PC–/– mice) die soon after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38fc9e6abf6054edc2c9c47986468dd
https://doi.org/10.1172/jci24030
https://doi.org/10.1172/jci24030
Autor:
Haifeng Xu, J. Andrew Martin, Zhong Liang, Elliot D. Rosen, Francis J. Castellino, Mark A. Suckow
Publikováno v:
Thrombosis and Haemostasis. 94:493-497
SummaryIt has been shown earlier that mice with a total targeted deletion of the factorVII gene (FVII-/-) die perinatally, thereby precluding study of adult animals with this total deficiency. Consequently, mice producing very low levels of FVII were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::411ca785b1f3a985903c4ef34225919f
https://doi.org/10.1160/th05-05-0337
https://doi.org/10.1160/th05-05-0337
Autor:
Elliot D. Rosen
Publikováno v:
Frontiers in Bioscience. 7:d1915-1925
Blood coagulation Factor X (FX) is a vitamin K-dependent serine protease that plays a central role in blood clotting. Additionally, FX may exert other functions beyond coagulation but the precise role of this protein in these processes and the in viv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91b56734b0560f26dbb946943d072e5
https://doi.org/10.2741/a888
https://doi.org/10.2741/a888