Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Elliot Chiang"'
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Peptide Mimetics of Thyrotropin-Releasing Hormone Based on a Cyclohexane Framework: Design, Synthesis, and Cognition-Enhancing Properties
Autor: Gary L. Olson, Elliot Chiang, George Vincent, Andrew Winokur, H.-C. Cheung, Keith A. Gary, Jerry Sepinwall, Vincent S. Madison
Publikováno v: Journal of Medicinal Chemistry. 38:2866-2879
The design and synthesis of peptide mimetics of thyrotropin-releasing hormone (TRH) in which the peptide backbone is entirely replaced by a cyclohexane framework are described. The cis-1,3,5-trisubstituted ring was expected to permit key pharmacophor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2d91f9a32b12d9ef62233044217484
https://doi.org/10.1021/jm00015a009
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2
ChemInform Abstract: Peptide Mimetics of Thyrotropin-Releasing Hormone Based on a Cyclohexane Framework: Design, Synthesis, and Cognition-Enhancing Properties
Autor: Elliot Chiang, Vincent S. Madison, Keith A. Gary, H.-C. Cheung, George Vincent, Andrew Winokur, Gary L. Olson, Jerry Sepinwall
Publikováno v: ChemInform. 26
The design and synthesis of peptide mimetics of thyrotropin-releasing hormone (TRH) in which the peptide backbone is entirely replaced by a cyclohexane framework are described. The cis-1,3,5-trisubstituted ring was expected to permit key pharmacophor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14da798dab2308731d01db0cbd697501
https://doi.org/10.1002/chin.199547242
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3
Structure activity of C-terminal modified analogs of Ac-CCK-7
Autor: Shian-Jan Shiuey, Joseph Triscari, Waleed Danho, Sally Weatherford, Raymond Makofske, Gary L. Olson, I. D. Kulesha, Francisca Y. Chiruzzo, Elliot Chiang, Joseph Michalewsky, Ramakanth Sarabu, Jefferson Wright Tilley, Victoria K. Rusieckt, David Nelson, Rolf Wagner, Joseph Swistok
Publikováno v: International journal of peptide and protein research. 39(4)
Previous work indicates that both the C-terminal phenylalanine amide and the tryptophan moieties of cholecystokinin (CCK) are critical pharmacophores for interaction with either the A or B receptor subtypes. We have examined a series of analogs of Ac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861a5fefb1f93fe261a5cc7b8ffcbc08
https://pubmed.ncbi.nlm.nih.gov/1385345
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