Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Elliot C Woods"'
Autor:
Elliot C Woods, FuiBoon Kai, J Matthew Barnes, Kayvon Pedram, Michael W Pickup, Michael J Hollander, Valerie M Weaver, Carolyn R Bertozzi
Publikováno v:
eLife, Vol 6 (2017)
Metastasis depends upon cancer cell growth and survival within the metastatic niche. Tumors which remodel their glycocalyces, by overexpressing bulky glycoproteins like mucins, exhibit a higher predisposition to metastasize, but the role of mucins in
Externí odkaz:
https://doaj.org/article/57d15b33b0224ade94a986318753f5e6
Autor:
Blaine W. Robinson, John A. Kairalla, Meenakshi Devidas, Andrew J. Carroll, Richard C. Harvey, Nyla A. Heerema, Cheryl L. Willman, Amanda R. Ball, Elliot C. Woods, Nancy C. Ballantyne, Karen A. Urtishak, Frederick G. Behm, Gregory H. Reaman, Joanne M. Hilden, Bruce M. Camitta, Naomi J. Winick, Jeanette Pullen, William L. Carroll, Stephen P. Hunger, ZoAnn E. Dreyer, Carolyn A. Felix
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/a81f0f0ee683429b9b3345bbb4014ff4
Autor:
Natalia Rodrigues Mantuano, Elliot C. Woods, Carolyn R. Bertozzi, Heinz Läubli, Payton A. Weidenbacher, Han Xiao, Green Ahn, Stacy A. Malaker, Caitlyn L. Miller, Johan F. A. Pijnenborg, Michal A. Stanczak, Melissa A. Gray, Julia T. Tanzo
Publikováno v:
Nat Chem Biol
Currently approved immune checkpoint inhibitor therapies targeting the PD-1 and CTLA-4 receptor pathways are powerful treatment options for certain cancers; however, most patients across cancer types still fail to respond. Consequently, there is inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6b87b21aa74b39d9dabf921ca0f6b8
https://doi.org/10.1038/s41589-020-0622-x
https://doi.org/10.1038/s41589-020-0622-x
Autor:
Melissa Gray, Michal A. Stanczak, Han Xiao, Johan F. A. Pijnenborg, Natália R. Mantuano, Stacy A. Malaker, Payton A. Weidenbacher, Caitlyn L. Miller, Julia T. Tanzo, Green Ahn, Elliot C. Woods, Heinz Läubli, Carolyn Bertozzi
Currently approved immune checkpoint inhibitor (ICI) therapies targeting the PD-1 and CTLA-4 receptor pathways are powerful treatment options for certain cancers; however, the majority of patients across cancer types still fail to respond. Addressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2037ee1e367878be40092dc190e63123
https://doi.org/10.26434/chemrxiv.8187146.v2
https://doi.org/10.26434/chemrxiv.8187146.v2
Autor:
Melissa A. Gray, Carolyn R. Bertozzi, Tanzo Jt, Michal A. Stanczak, Pijnenborg Jfa, Heinz Läubli, Payton A. Weidenbacher, Green Ahn, Elliot C. Woods, Stacy A. Malaker, Xiao H
Currently approved immune checkpoint inhibitor (ICI) therapies targeting the PD-1 and CTLA-4 receptor pathways are powerful treatment options for certain cancers; however, the majority of patients across cancer types still fail to respond. Addressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b582a0415ee29cd96fafa17b6f44ddf
https://doi.org/10.26434/chemrxiv.8187146.v1
https://doi.org/10.26434/chemrxiv.8187146.v1
Autor:
Michael J. Ferracane, Barbara A. Bensing, Elliot C. Woods, Oliver Dorigo, Carolyn R. Bertozzi, Jessica R. Kramer, Kayvon Pedram, Christian Pett, Venkatesh Krishnan, Ulrika Westerlind, Stacy A. Malaker, Jin Yu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(15)
Mucin domains are densely O-glycosylated modular protein domains that are found in a wide variety of cell surface and secreted proteins. Mucin-domain glycoproteins are known to be key players in a host of human diseases, especially cancer, wherein mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e0472918d5d3863413e3133eab222e
https://pubmed.ncbi.nlm.nih.gov/30910957
https://pubmed.ncbi.nlm.nih.gov/30910957
Publikováno v:
Proceedings of the National Academy of Sciences. 113:10304-10309
Cell surface sialosides constitute a central axis of immune modulation that is exploited by tumors to evade both innate and adaptive immune destruction. Therapeutic strategies that target tumor-associated sialosides may therefore potentiate antitumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a06d8a2e123da75b0af15ac0f6b4de2
https://doi.org/10.1073/pnas.1608069113
https://doi.org/10.1073/pnas.1608069113
Autor:
Boris Hinz, Wolfgang Bergmeier, Wendy Furuya, Carolyn R. Bertozzi, Sergio Grinstein, Jesse Goyette, P. Anton van der Merwe, Elliot C. Woods, Raibatak Das, Spencer A. Freeman
Publikováno v:
Cell. 164(1-2):128-140
Phagocytosis is initiated by lateral clustering of receptors, which in turn activates Src-family kinases (SFKs). Activation of SFKs requires depletion of tyrosine phosphatases from the area of particle engagement. We investigated how the major phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39f4a0a5b92193c75ab5d8f567374e5
Autor:
Michael J. Ferracane, Stacy A. Malaker, Elliot C. Woods, Jessica R. Kramer, Oliver Dorigo, Carolyn R. Bertozzi, Kayvon Pedram
Mucins are a class of highly O-glycosylated proteins that are ubiquitously expressed on cellular surfaces and are important for human health, especially in the context of carcinomas. However, the molecular mechanisms by which aberrant mucin structure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e884c0797892265308e8e5aaa10cdca
https://doi.org/10.26434/chemrxiv.7330676
https://doi.org/10.26434/chemrxiv.7330676
Autor:
Richard F. Collins, Spencer A. Freeman, Anthony Vega, Elliot C. Woods, Diane S. Lidke, Magdalena Riedl, Khuloud Jaqaman, Carolyn R. Bertozzi, Markku Tammi, Sergio Grinstein, Satyajit Mayor, Pauline Johnson
Publikováno v:
SSRN Electronic Journal.
Phagocytic receptors must diffuse laterally to become activated upon clustering by multivalent targets. Receptor diffusion, however, can be obstructed by transmembrane proteins ("pickets") that are immobilized by interacting with the cortical cytoske
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43d095bf344ac547b5c56a001d326146
https://doi.org/10.2139/ssrn.3155516
https://doi.org/10.2139/ssrn.3155516