Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Elliot B. Gordon"'
Autor:
Charles E. Wood, Deborah M. Proctor, Samuel M. Cohen, Chad M. Thompson, Elliot B. Gordon, Mark A. Harris, John M. Cullen, Virunya S. Bhat
Publikováno v:
Critical reviews in toxicology. 50(8)
Small intestinal (SI) tumors are relatively uncommon outcomes in rodent cancer bioassays, and limited information regarding chemical-induced SI tumorigenesis has been reported in the published literature. Herein, we propose a cytotoxicity-mediated ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5dc893e0fa7d96925c53a6af13ff7b
https://pubmed.ncbi.nlm.nih.gov/33146058
https://pubmed.ncbi.nlm.nih.gov/33146058
Autor:
Barbara H. Neal, Frederick G. Hess, Sandeep Mukhi, David R. Geter, Leah D. Stuchal, Christopher J. Borgert, Catherine M. Holmes, Lisa S. Ortego, John M. Brausch, Ellen Mihaich, Suzanne I. Snajdr, Abraham Tobia, Sue Marty, Karin S. Bentley, Jane P. Staveley, Katie Coady, David Saltmiras, Steve L. Levine, Patrick D. Guiney, Matthew J. LeBaron, Elliot B. Gordon, Richard A. Becker
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 101:90-113
Weight of evidence (WoE) approaches are recommended for interpreting various toxicological data, but few systematic and transparent procedures exist. A hypothesis-based WoE framework was recently published focusing on the U.S. EPA's Tier 1 Endocrine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ae6a956a658ad7ac7c5b8da45190d2
https://doi.org/10.1002/bdrb.21096
https://doi.org/10.1002/bdrb.21096
Autor:
Samuel M. Cohen, Klaus Weber, Deborah A. Banas, Elliot B. Gordon, Christian Strupp, Martina Jaeger
Publikováno v:
Toxicological Sciences
Species-specific lung tumors in the mouse are induced by a number of chemicals. The underlying cause appears to be a high metabolic activity of mouse lung, due to relatively high abundance of Clara cells in mice compared with humans and the mouse-spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2402a1745897c0a87bd77e22f575b16
https://doi.org/10.1093/toxsci/kfs127
https://doi.org/10.1093/toxsci/kfs127
Autor:
Elliot B. Gordon
Publikováno v:
Journal of Applied Toxicology. 27:519-526
On 24 November 2004 EPA changed the cancer classification of captan from a 'probable human carcinogen' (Category B2) to 'not likely' when used according to label directions. The new cancer classification considers captan to be a potential carcinogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cfccdd12edb37530139319e1d125eb
https://doi.org/10.1002/jat.1265
https://doi.org/10.1002/jat.1265
Autor:
Linda A. Malley, Elliot B. Gordon
Publikováno v:
The Role of the Study Director in Nonclinical Studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dddc5c7418e6e02c7ec958931aeb7c5d
https://doi.org/10.1002/9781118873922.ch26
https://doi.org/10.1002/9781118873922.ch26
Autor:
Elliot B. Gordon, William G. Reed
Publikováno v:
Building Research & Information. 28:325-337
The integrated design process encompasses cross-disciplinary teamwork enabling the improved integration of building, community, natural and economic systems and therefore is a key to sustainable design. The needs for further research, methodologies a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaf0f971621b88096a687d863b19f577
https://doi.org/10.1080/096132100418483
https://doi.org/10.1080/096132100418483
Autor:
Bruce K. Bernard, Elliot B. Gordon
Publikováno v:
International Journal of Toxicology. 19:43-61
Under the Food Quality Protection Act (FQPA) of 1996 (Act), the United States Environmental Protection Agency (EPA) is mandated to conduct cumulative risk assessment on pesticides that act through a common mechanism of toxicity. Incumbent on the Agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9002628d859b605d39a4d7acac244ef5
https://doi.org/10.1080/109158100225033
https://doi.org/10.1080/109158100225033
Publikováno v:
Toxicology mechanisms and methods. 22(1)
Folpet, an agricultural fungicide, induces tumors in the mouse gastrointestinal tract, primarily in the duodenum. Bioassays show a threshold for tumors at ~1000 ppm dietary administration. We investigated the early histologic changes to the mouse duo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ea7b278b66c397ac8c88b2fc99fb28
https://pubmed.ncbi.nlm.nih.gov/22017358
https://pubmed.ncbi.nlm.nih.gov/22017358
Publikováno v:
Critical reviews in toxicology. 40(6)
Folpet and captan are fungicides whose genotoxicity depends on their chemical reaction with thiols. Multiple mutagenicity tests have been conducted on these compounds due to their positive activity in vitro and their association with gastrointestinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b7af8e2bfcb57863df125d5e4d735b
https://pubmed.ncbi.nlm.nih.gov/20569196
https://pubmed.ncbi.nlm.nih.gov/20569196
Publikováno v:
Critical reviews in toxicology. 40(6)
A framework has been evolving for evaluation of mode of action (MOA) of rodent toxicity and carcinogenicity findings and their relevance to humans. Folpet produces duodenal glandular tumors in mice, but is not carcinogenic in rats. A wealth of inform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8538a1578cda304d256bddcb0fbb4570
https://pubmed.ncbi.nlm.nih.gov/20521864
https://pubmed.ncbi.nlm.nih.gov/20521864