Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Elliot, Imler"'
Autor:
Elliot Imler, Jin Sang Pyon, Selina Kindelay, Meaghan Torvund, Yong-quan Zhang, Sreeganga S Chandra, Konrad E Zinsmaier
Publikováno v:
eLife, Vol 8 (2019)
The autosomal dominant neuronal ceroid lipofuscinoses (NCL) CLN4 is caused by mutations in the synaptic vesicle (SV) protein CSPα. We developed animal models of CLN4 by expressing CLN4 mutant human CSPα (hCSPα) in Drosophila neurons. Similar to pa
Externí odkaz:
https://doaj.org/article/f2b8e28170ce43eca67cf76ac007b248
Autor:
Christy L Trejo, Miloš Babić, Elliot Imler, Migdalia Gonzalez, Sergei I Bibikov, Peter J Shepard, Harper C VanSteenhouse, Joanne M Yeakley, Bruce E Seligmann
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212031 (2019)
We describe the use of a ligation-based targeted whole transcriptome expression profiling assay, TempO-Seq, to profile formalin-fixed paraffin-embedded (FFPE) tissue, including H&E stained FFPE tissue, by directly lysing tissue scraped from slides wi
Externí odkaz:
https://doaj.org/article/24977ed9ec084aca885a049108f285f0
Autor:
Kenneth Steadman, Gregory S. Parker, Geoffray Leriche, Sarah Fish, Julia Toth, Mary E. Spalding, Elizabeth Daniele, Aleksandar Jamborcic, Xiaoming Li, E Adam Kallel, Farhana Barmare, Kenneth Chng, Erika Green, Michael Hocker, Elliot Imler, Yi Zhang, Peggy A. Thompson, Simon Bailey
Publikováno v:
Cancer Research. 82:421-421
Prostate cancer is the second most common cause of cancer related deaths in men in the United States. Pathogenesis is driven by the androgen receptor (AR), which has led to front-line treatment modalities that are based on androgen deprivation therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89979bbcc05eda7e0c41ec9a438709f5
https://doi.org/10.1158/1538-7445.am2022-421
https://doi.org/10.1158/1538-7445.am2022-421
Autor:
Erika Bracamonte, Robert C. Bell, Elinora Price, B. Seligmann, Tijana Milinic, Elliot Imler, Benjamin R. Lee, Aye Lwin, Ken Batai, Amit Arora, Jayce Pangilinan, Nathan A. Ellis
Publikováno v:
Genes & Cancer
Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of kidney cancer, yet molecular biomarkers have not been used for the prognosis of ccRCC to aide clinical decision making. This study aimed to identify genes associated with ccRCC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23e0c9ec55cabd4863cdfa7966f54f08
https://doi.org/10.18632/genesandcancer.183
https://doi.org/10.18632/genesandcancer.183
Autor:
Amanda F. Baker, Marilyn T. Marron, Linda L. Garland, Neale T. Hanke, Elliot Imler, Bruce Seligmann
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 144:1317-1327
We previously showed that carfilzomib (CFZ) has potent anti-proliferative and cytotoxic activity in a broad range of lung cancer cell lines. Here we investigate possible mechanisms of CFZ acquired resistance in lung cancer cell lines. CFZ-resistant n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b3d460bca505e095100ff7aff9f9c04
https://doi.org/10.1007/s00432-018-2662-0
https://doi.org/10.1007/s00432-018-2662-0
Autor:
Konrad E. Zinsmaier, Meaghan Torvund, Sreeganga S. Chandra, Selina Kindelay, Jin Sang Pyon, Elliot Imler, Yong-quan Zhang
Publikováno v:
eLife, Vol 8 (2019)
The autosomal dominant neuronal ceroid lipofuscinoses (NCL) CLN4 is caused by mutations in the synaptic vesicle (SV) protein CSPα. We developed animal models of CLN4 by expressing CLN4 mutant human CSPα (hCSPα) in Drosophila neurons. Similar to pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e6e19e4978c015fd662eecca67baa3
https://doi.org/10.7554/elife.46607
https://doi.org/10.7554/elife.46607
Autor:
Jin Sang Pyon, Sreeganga S. Chandra, Yong-quan Zhang, Konrad E. Zinsmaier, Elliot Imler, Selina Kindelay
The autosomal dominant neuronal ceroid lipofuscinoses (NCL)CLN4is caused by mutations in the synaptic vesicle (SV) protein CSPα, which is a critical co-chaperone of Hsc70 protecting synapses from activity-dependent degeneration. We developed the fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4026d8c10cb1f777b8f9aaeb36d7dd
Autor:
Elliot, Imler, Jin Sang, Pyon, Selina, Kindelay, Meaghan, Torvund, Yong-Quan, Zhang, Sreeganga S, Chandra, Konrad E, Zinsmaier
Publikováno v:
eLife
Experiments on flies suggest that a gain-of-function mechanism in a protein called CSPɑ contributes to the progressive brain disease CLN4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a839f8ffc0f24cfa79c22f14f43747f
https://pubmed.ncbi.nlm.nih.gov/31808420
https://pubmed.ncbi.nlm.nih.gov/31808420
Autor:
Sergei I. Bibikov, Harper C. VanSteenhouse, Elliot Imler, Milos Babic, Joanne M. Yeakley, Christy L. Trejo, Peter J. Shepard, Migdalia Gonzalez, Bruce Seligmann
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212031 (2019)
PLoS ONE
PLoS ONE
We describe the use of a ligation-based targeted whole transcriptome expression profiling assay, TempO-Seq™, to profile formalin-fixed paraffin-embedded (FFPE) tissue, including H&E stained FFPE tissue, by directly lysing tissue scraped from slides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d159a8cd5ce2c3a85149c38ca9ddff
Autor:
Tijana Milinic, Ken Batai, Bruce Seligmann, Robert J.A. Bell, Elliot Imler, Elinora Price, Aye Lwin, Michael Phung, Erika Bracamonte, Benjamin R. Lee
Publikováno v:
Journal of Urology. 199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::475963ca118e6479d0eb1d58019546b1
https://doi.org/10.1016/j.juro.2018.02.2645
https://doi.org/10.1016/j.juro.2018.02.2645