Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ellie Tzima"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The cardiovascular system can sense and adapt to changes in mechanical stimuli by remodeling the physical properties of the heart and blood vessels in order to maintain homeostasis. Imbalances in mechanical forces and/or impaired sensing are now not
Externí odkaz:
https://doaj.org/article/bc6e795fd0424cc68b30c544c4fe215a
Publikováno v:
Cells, Vol 9, Iss 3, p 650 (2020)
Mechanical forces acting on biological systems, at both the macroscopic and microscopic levels, play an important part in shaping cellular phenotypes. There is a growing realization that biomolecules that respond to force directly applied to them, or
Externí odkaz:
https://doaj.org/article/b9c852af91ae4b87a60d13e5b8a94f62
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109325 (2014)
A naturally-occurring fragment of tyrosyl-tRNA synthetase (TyrRS) has been shown in higher eukaryotes to 'moonlight' as a pro-angiogenic cytokine in addition to its primary role in protein translation. Pro-angiogenic cytokines have previously been pr
Externí odkaz:
https://doaj.org/article/27b1f19dd8394b06ba0d283e4b6abda3
Publikováno v:
Current Opinion in Physiology. 34:100673
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85931c7b7f6f72ecbf995263710f6601
https://doi.org/10.1016/j.cophys.2023.100673
https://doi.org/10.1016/j.cophys.2023.100673
Autor:
Adam N. Keen, Luke A. Payne, Vedanta Mehta, Alistair Rice, Lisa J. Simpson, Kar Lai Pang, Armando del Rio Hernandez, John S. Reader, Ellie Tzima
Publikováno v:
The Journal of Cell Biology
Keen et al. discover a new role for eIF6, a protein classically known for its role in protein synthesis, in mechanotransduction, and the cellular response to force. These data provide a novel paradigm for how the cytoskeletal and translational machin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f6140ec265288b55a03f0ff86a9645
https://doi.org/10.1083/jcb.202005213
https://doi.org/10.1083/jcb.202005213
Autor:
Keith M. Channon, Surawee Chuaiphichai, Gillian Douglas, Lucy Trelfa, Lucy Donovan, Edward Drydale, Theodosios Kyriakou, Ioannis Akoumianakis, Charalambos Antoniades, Anuj Goel, Vedanta Mehta, Ayman Al Haj Zen, Ellie Tzima, Hugh Watkins, Victoria S Rashbrook
Publikováno v:
Cardiovascular Research
INTRODUCTION: Genome Wide Association studies have consistently identified an association between coronary artery disease (CAD) and a locus on chromosome 10 containing a single gene, JCAD (formerly KIAA1462). However, little is known about the mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fd437a428577a223bed4042c83aa09
http://europepmc.org/articles/PMC7449560
http://europepmc.org/articles/PMC7449560
BackgroundHaemodynamic forces play a critical role in proper development of the heart, however much less is known about the mechanisms that regulate cardiac remodelling and function in response to haemodynamic stress in the adult. Platelet endothelia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::045c555eb383e7e9c0456db67e7c7769
https://doi.org/10.1101/2021.01.15.426661
https://doi.org/10.1101/2021.01.15.426661
Autor:
Adam Keen, Luke Payne, Alistair Rice, Lisa Simpson, Kar Lai Pang, Armando del Río Hernández, John Reader, Ellie Tzima
The authors have requested that this preprint be removed from Research Square.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db8ed22699a9193f4024d7006ab1791f
https://doi.org/10.21203/rs.3.rs-115842/v1
https://doi.org/10.21203/rs.3.rs-115842/v1
Autor:
Vedanta Mehta, Kar-Lai Pang, Daniel Rozbesky, Katrin Nather, Adam Keen, Dariusz Lachowski, Youxin Kong, Dimple Karia, Michael Ameismeier, Jianhua Huang, Yun Fang, Armando del Rio Hernandez, John S. Reader, E. Yvonne Jones, Ellie Tzima
Publikováno v:
Nature. 605:E6-E6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0483649bb6b3ba5d0da4f4cfa305ae6
https://doi.org/10.1038/s41586-022-04815-w
https://doi.org/10.1038/s41586-022-04815-w
Autor:
Vedanta Mehta, A. del Rio Hernandez, Josh Huang, Ellie Tzima, K Nather, John S. Reader, Yun Fang, Dariusz Lachowski, D. Karia, M Ameismeier, Pang K-L., E Y Jones, D. Rozbesky, A Keen, Y Kong
Shear stress on arteries produced by blood flow is important for vascular development and homeostasis but can also initiate atherosclerosis1. Endothelial cells that line the vasculature use molecular mechanosensors to directly detect shear stress pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1081296a65b9d3a4a7807c6604c3965
http://hdl.handle.net/10044/1/92397
http://hdl.handle.net/10044/1/92397