Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ellie Rad"'
Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8a5101373f187734d2fe36ca1c305f
https://doi.org/10.1158/1541-7786.22511289
https://doi.org/10.1158/1541-7786.22511289
Supplementary Figure 1. ST8814 and S462 cells have markedly different STAT3 signalling profiles after HGF stimulation. Starved ST8814 and S462 cells were stimulated with 20 ng/ml HGF for the indicated time (0 h, 1 h, 2 h, and 3 h). Total and phosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd6e1901f9292b3078f92b6673c74fe
https://doi.org/10.1158/1541-7786.22511295
https://doi.org/10.1158/1541-7786.22511295
Supplementary Figure 2. Cucurbitacin-I greatly altered the morphology of the S1844.1 and S1507.2 cell lines. Starved S1844.1 and S1507.2 cells were subjected to wound healing assay. Cells were pre-treated with 5 nM Cucurbitacin-I, for 30 min prior to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965973042cbc0563e4ac67b3faf00d13
https://doi.org/10.1158/1541-7786.22511292.v1
https://doi.org/10.1158/1541-7786.22511292.v1
Autor:
Yan Tong, Silpa Gampala, Ellie Rad, Ren Yuan Bai, Olivia Babb, Emily Hulsey, Fenil Shah, Chi Zhang, Steven D. Rhodes, Verena Staedtke, Randall Wireman, Brian L. Calver, Mark R. Kelley, Michelle Grimard, M. Reza Saadatzadeh, Abbi Smith, D. Wade Clapp, Andrew R. Tee, Karen E. Pollok, Melissa L. Fishel
Publikováno v:
British Journal of Cancer
Background MPNST is a rare soft-tissue sarcoma that can arise from patients with NF1. Existing chemotherapeutic and targeted agents have been unsuccessful in MPNST treatment, and recent findings implicate STAT3 and HIF1-α in driving MPNST. The DNA-b
Autor:
Silpa Gampala, Fenil Shah, Chi Zhang, Steven D. Rhodes, Olivia Babb, Michelle Grimard, Randall S. Wireman, Ellie Rad, Brian Calver, Ren-Yuan Bai, Verena Staedtke, Emily L. Hulsey, M. Reza Saadatzadeh, Karen E. Pollok, Yan Tong, Abbi E. Smith, D. Wade Clapp, Andrew R. Tee, Mark R. Kelley, Melissa L. Fishel
Publikováno v:
British Journal of Cancer. 127:1378-1379
Autor:
Jesse D. Champion, Kayleigh M. Dodd, Hilaire C. Lam, Mohammad A. M. Alzahrani, Sara Seifan, Ellie Rad, David Oliver Scourfield, Melissa L. Fishel, Brian L. Calver, Ann Ager, Elizabeth P. Henske, David Mark Davies, Mark R. Kelley, Andrew R. Tee
Publikováno v:
Cancers; Volume 14; Issue 24; Pages: 6195
Therapies with the mechanistic target of rapamycin complex 1 (mTORC1) inhibitors are not fully curative for tuberous sclerosis complex (TSC) patients. Here, we propose that some mTORC1-independent disease facets of TSC involve signaling through redox
Autor:
Andrew R. Tee, Ellie Rad
Publikováno v:
Seminars in Cell & Developmental Biology. 52:39-46
Neurofibromatosis type 1 (NF1) is an autosomal dominant tumour predisposition syndrome that is caused through loss of function mutations of a tumour suppressor gene called Neurofibromin 1. Therapeutic options are currently limited for NF1-associated
Autor:
Melissa L. Fishel, Silpa Gampala, Mark R. Kelley, D. Wade Clapp, Brian L. Calver, Ellie Rad, Emily Zhang, Steven D Rhodes, Fenil Shah, Andrew R. Tee, Olivia Babb, Verena Staedtke, Karen E. Pollok, Chi Zhang
Publikováno v:
Molecular Cancer Therapeutics. 18:C017-C017
Malignant Peripheral Nerve Sheath Tumor (MPNST) is a rare soft tissue sarcoma that can arise from patients with NF1 (neurofibromatosis type 1). These patients are at a much greater risk of developing MPNST than the general population (10% vs. 0.01%,
Publikováno v:
Cancers
Throughout the years, research into signalling pathways involved in cancer progression has led to many discoveries of which mechanistic target of rapamycin (mTOR) is a key player. mTOR is a master regulator of cell growth control. mTOR is historicall
Therapeutic options are limited for neurofibromatosis type 1 (NF1)-associated malignant peripheral nerve sheath tumors (MPNST) and clinical trials using drug agents have so far been unsuccessful. This lack of clinical success is likely attributed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3fd8a789586e7cef21e5aa155950bc5
https://cronfa.swan.ac.uk/Record/cronfa54838
https://cronfa.swan.ac.uk/Record/cronfa54838