Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Elli Kruithof"'
Publikováno v:
Arthritis and rheumatism, 58(3), 730-733. John Wiley and Sons Inc.
The highly effective treatment of rheumatoid arthritis by B cell depletion and the presence of B cells in the peripheral and axial lesions of patients with spondylarthritis (SpA) raise the question as to whether B lymphocytes could also be an appropr
Autor:
Rik Joos, Eric Veys, Bernard Vandooren, Paul P. Tak, Annemieke M. H. Boots, Juan D. Cañete, Veronique Van den Bossche, Elli Kruithof, Dominique Baeten, Leen De Rycke
Publikováno v:
Arthritis and rheumatism, 54(8), 2594-2604. John Wiley and Sons Inc.
Objective To characterize the synovial immunopathologic features of juvenile-onset spondylarthritis (SpA) in relation to adult SpA and other forms of juvenile idiopathic arthritis (JIA). Methods Synovial biopsy samples were obtained from 10 patients
Autor:
Dominique Baeten, Eric Veys, Elli Kruithof, Oliver FitzGerald, Paul P. Tak, Iain B. McInnes, Barry Bresnihan, Leen De Rycke, Bernard Vandooren, Filip De Keyser
Publikováno v:
Arthritis and rheumatism, 54(6), 1795-1804. John Wiley and Sons Inc.
Objective To identify biomarkers for effective treatment in early-phase clinical trials of spondylarthritis (SpA), by analyzing which synovial features can be reliably identified in patients with SpA. Methods Synovial biopsies were performed at weeks
Autor:
Leen De Rycke, Filip Van den Bosch, Dominique Baeten, Elli Kruithof, Filip De Keyser, Eric Veys
Publikováno v:
Arthritis and rheumatism, 52(7), 2192-2201. John Wiley and Sons Inc.
Objective To analyze the clinical and biologic correlates of autoantibody induction during longer-term tumor necrosis factor α (TNFα) blockade with either the monoclonal antibody infliximab or the soluble receptor etanercept. Methods Thirty-four pa
Autor:
Tineke Cantaert, Elli Kruithof, Leen De Rycke, Filip De Keyser, Anthony P. Nicholas, Bart Vandekerckhove, Dominique Baeten, Eric Veys, Joshua D. Echols
Publikováno v:
Arthritis and rheumatism, 52(8), 2323-2330. John Wiley and Sons Inc.
Objective To address the ongoing debate concerning the specificity of synovial citrullinated proteins for rheumatoid arthritis (RA) and to analyze their pathophysiologic relevance to the induction or perpetuation of the RA-specific anti–citrullinat
Autor:
Elli Kruithof, Filip De Keyser, Herman Mielants, Filip Van den Bosch, Eric Veys, Gust Verbruggen, Dominique Baeten
Publikováno v:
Drugs. 64:2793-2811
Spondylarthropathies (SpA) present mainly with spondylitis, pauciarticular peripheral arthritis and enthesopathy. Ankylosing spondylitis (AS) is the prototype disease in this concept. Other entities include reactive arthritis, arthritis in patients w
Autor:
Bernard Vandooren, Filip Van den Bosch, Filip De Keyser, Dominique Baeten, Eric Veys, Elli Kruithof, Markus Rihl, Jieruo Gu, David T. Y. Yu, Leen De Rycke
Publikováno v:
Arthritis and rheumatism, 50(9), 2942-2953. John Wiley and Sons Inc.
Objective To investigate the role of matrix metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in spondylarthropathy (SpA) synovitis. Methods Paired samples of synovial biopsy tissue as well as serum and synovial flu
Autor:
Herman Mielants, E M Veys, N Van den Bossche, A Herssens, Dominique Baeten, F De Keyser, Elli Kruithof, F. Van den Bosch
Publikováno v:
Annals of the rheumatic diseases, 62(9), 829-834. BMJ Publishing Group
Background: Recent studies with infliximab indicate the therapeutic potential of tumour necrosis factor α blockade in spondyloarthropathy (SpA). Because defective host defence is implicated in the pathogenesis of SpA, the potential side effects of t
Autor:
Leen De Rycke, Eric Veys, Filip Van den Bosch, Elli Kruithof, Nancy Van Damme, Ilse Hoffman, Filip De Keyser, Nancy Van den Bossche
Publikováno v:
Arthritis & Rheumatism. 48:1015-1023
Objective To investigate the effect of infliximab treatment on antinuclear antibodies (ANAs), anti–double-stranded DNA (anti-dsDNA), antinucleosome, antihistone, and anti–extractable nuclear antigen (anti-ENA) antibodies in rheumatoid arthritis (
Autor:
Herman Mielants, Filip De Keyser, Eric Veys, Elli Kruithof, Filip Van den Bosch, Dominique Baeten
Publikováno v:
Rheumatic diseases clinics of North America, 29(3), 463-479. W.B. Saunders Ltd
A major breakthrough has been achieved in the treatment of patients who have AS and other types of SpA. The identification of the expression and role of TNF-alpha in patients who have these diseases and the recognition of their relation with gut infl